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Published 2008 | Version v1.0.0
Journal Article Open

Reversible Valproate Hepatotoxicity and Associated Mitochondrial Disease

Abstract

A 2-year-old boy with seizures complicated by reversible valproate-induced hepatic failure was subsequently found to have mitochondrial polymerase g gene (POLG1) mutations typical of Alpers-Huttenlocher disease, in a study at Newcastle University, UK.

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Created:
March 30, 2023
Modified:
March 30, 2023