Topiramate Adjunctive Therapy for Partial Seizures

Abstract

The efficacy and safety of topiramate (TPM) (6 mg/kg/day) in children age 2 to 16 years, as adjunctive therapy for uncontrolled partial-onset seizures (75% complex partial), with or without secondarily generalized seizures, were evaluated in a multicenter, randomized, double-blind, placebo-controlled trial, organized by the Topiramate YP Study Group.

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