Tourette Syndrome and Streptococcal Infection

Abstract

Serum antibodies against human caudate, putamen, and globus pallidus were assayed by enzyme-linked immunosorbent assay (ELISA) and Western blot techniques in 41 children (mean age, 11 years) with Tourette syndrome (TS) and 39 controls, and results were correlated with clinical findings and markers of streptococcal infection (antistreptolysin O (ASO) and antideoxyribonuclease B (antiDNAse-B)), in a study at Johns Hopkins Hospital, Baltimore, MD.

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