Carbamazepine and Cognitive Impairment

Abstract

Members of the Departments of Pediatrics, Neurology, and Clinical Pharmacology and Toxicology at the Childrens Hospital and Ohio State University, Columbus, OH 43205, assessed neuropsychological function before and after carbamazepine monotheraphy at low ( <-7.5,ug/ml) and moderate (>8.0,ug/ml) plasma levels in 11 children (4 boys 7 girls, mean age 9.8 yrs) with controlled complex partial epilepsy.

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