Valproate Hepatotoxicity in Children with Epilepsy

Creators: Millichap, J. Gordon

Abstract

Authors from the University Childrens Hospital in Heidelberg estimate the incidence of fatal valproate (VPA) hepatotoxicity in West Germany at around 1 in 5000 and find it hard to justify the use of VPA as a drug of first choice for children with generalised epilepsies.

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