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Recent advances in gene therapy for atrial fibrillation Open Access (recommended)

Descriptions

Resource type(s)
Journal Article
Keyword
Gene Therapy
Atrial Fibrillation
Rights
All rights reserved
Creator
Rottmann, Markus
Yoo, Shin
Geist, Gail Elizabeth
Pfenniger, Anna
Arora, Rishi K
Abstract
Atrial fibrillation (AF) is the most common heart rhythm disorder in adults and a major cause of stroke. Unfortunately, current treatments for AF are suboptimal as they are not targeting the molecular mechanisms underlying AF. In this regard, gene therapy is emerging as a promising approach for mechanismbased treatment of AF. In this review, we summarize recent advances and challenges in gene therapy for this important cardiovascular disease.
Original Bibliographic Citation
Yoo S, Geist GE, Pfenniger A, Rottman M, Arora R. Recent advances in gene therapy for atrial fibrillation. J Cardiovasc Electrophysiol. 2021;32:28542864.
Publisher
Journal of Cardiovascular Electrophysiology
DigitalHub. Galter Health Sciences Library & Learning Center
Date Created
2021-05-30
Original Identifier
(DOI) 10.1111/jce.15116
Language
English
Subject: MESH
Atrial Fibrillation
Genetic Therapy
Grants and funding
AHA Strategically Focused Research Networks AF Center grant; NIH Center for Accelerated Innovations at Cleveland Clinic (NCAICC); National Heart, Lung, and Blood Institute, Grant/Award Numbers: RA: R01 HL093490, R01 HL140061
DOI
10.1111/jce.15116

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