Recent advances in gene therapy for atrial fibrillation

Abstract

Atrial fibrillation (AF) is the most common heart rhythm disorder in adults and a major cause of stroke. Unfortunately, current treatments for AF are suboptimal as they are not targeting the molecular mechanisms underlying AF. In this regard, gene therapy is emerging as a promising approach for mechanismbased treatment of AF. In this review, we summarize recent advances and challenges in gene therapy for this important cardiovascular disease.

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original_citation: Yoo S, Geist GE, Pfenniger A, Rottman M, Arora R. Recent advances in gene therapy for atrial fibrillation. J Cardiovasc Electrophysiol. 2021;32:28542864.

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