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Diaphragm dysfunction in severe COVID-19 as determined by neuromuscular ultrasound Open Access (recommended)

Farr E, Wolfe AR, Deshmukh S, Rydberg L, Soriano R, Walter JM, Boon AJ, Wolfe LF, Franz CK. Diaphragm dysfunction in severe COVID-19 as determined by neuromuscular ultrasound. Annals of Clinical and Translational Neurology. 2021;8(8):1745-1749.

Descriptions

Resource type(s)
Article
Keyword
COVID-19
Rights
Attribution-NonCommercial-NoDerivs 3.0 United States

Creator
Farr, Ellen Marie
Wolfe, Alexis R.
Deshmukh, Swati
Rydberg, Leslie Katherine
Soriano, Rachna
Walter, James McCauley
Boon, Andrea J.
Wolfe, Lisa F
Franz, Colin K
Abstract
Many survivors from severe coronavirus disease 2019 (COVID-19) suffer from persistent dyspnea and fatigue long after resolution of the active infection. In a cohort of 21 consecutive severe post-COVID-19 survivors admitted to an inpatient rehabilitation hospital, 16 (76%) of them had at least one sonographic abnormality of diaphragm muscle structure or function. This corresponded to a significant reduction in diaphragm muscle contractility as represented by thickening ratio (muscle thickness at maximal inspiration/end-expiration) for the post-COVID-19 compared to non-COVID-19 cohorts. These findings may shed new light on neuromuscular respiratory dysfunction as a contributor to prolonged functional impairments after hospitalization for post-COVID-19.
Related URL
Publisher
WILEY
Date Created
2021-08
Original Identifier
(PMID) 34247452
DOI
10.1002/acn3.51416

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