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- Title:
- Beyond an Apple a Day: finding reliable health information online post-session questionnaire
- Description:
- Pre and post session questionnaire for "Beyond an Apple a Day: Finding Reliable Health Information Online" given on March 3, 2015.
- Keyword:
- questionnaire, consumer health
- Subject: MESH:
- Consumer Health Information
- Creator:
- Gutzman, Karen E, Almader-Douglas, Diana
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2015-03-04
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Other
- Title:
- Beyond an Apple A Day: finding reliable health information online pre-session questionnaire
- Description:
- Pre and post session questionnaire for "Beyond an Apple a Day: Finding Reliable Health Information Online" given on March 3, 2015.
- Keyword:
- questionnaire, consumer health
- Subject: MESH:
- Consumer Health Information
- Creator:
- Gutzman, Karen E, Almader-Douglas, Diana
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2015-03-04
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Other
- Title:
- Beyond an Apple A Day: Finding Reliable Health Information Online
- Description:
- This presentation was given to older adult winter migrants known as snowbirds to help them find reliable online health information.
- Keyword:
- health information, consumer health, MedlinePlus, NIH Senior Health, KidsHealth
- Subject: MESH:
- Consumer Health Information, Aged, Child, Information Seeking Behavior
- Creator:
- Gutzman, Karen E, Almader-Douglas, Diana
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2015-03-04
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Presentation
- Title:
- Enhancing the Visibility and Impact of Your Research
- Description:
- Presentation given on October 20, 2015 for the Multidisciplinary Mentored Career Development Program (KL2) Scholar Orientation Bootcamp
- Keyword:
- research outputs, scholarly communication, dissemination, KL2, NUCATS
- Subject: MESH:
- Research
- Subject: LCSH:
- Scholarly publishing
- Creator:
- Gutzman, Karen E
- Contributor:
- Holmes, Kristi, Sarli, Cathy
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2014-11-20
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Presentation
- Title:
- Measuring Success Through Improved Attribution
- Description:
- Presentation at the VIVO 2015 Conference, August 14, 2015, Cambridge, MA
- Abstract:
- Measuring success through improved attribution As data science and informatics transform scholarly activities, the structure and composition of the typical scientific team is changing. Professionals from diverse backgrounds are now contributing fundamentally to discoveries and creative scholarly outputs, often in ways that cannot be quantified through traditional metrics of scholarly impact. To credit and evaluate the work of these important collaborators, we need mechanisms to capture such contributions. VIVO is well positioned to assist in the development of a standard mechanism for attribution and subsequent citation of these individuals creative contributions. With the goal of leading the way toward a computational model for collecting and disseminating contributor attribution data, this panel aims to identify stakeholders (researchers, developers, publishers, agencies), assess attribution requirements, and provide an interactive community forum to define innovative approaches to scientific attribution. Follow the conversation in this interactive session at #VIVOcredit.
- Keyword:
- scholarly communication, VIVO Conference (2015 : Cambridge, Mass.), Attribution, Contribution, research outputs, credit
- Subject: MESH:
- Achievement, Evaluation Studies as Topic, Authorship
- Subject: LCSH:
- Communication in learning and scholarship, Research
- Creator:
- Gutzman, Karen E, Holmes, Kristi, Haendel, Melissa, Konkiel, Stacy
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Cambridge, Massachusetts, United States
- Language:
- English
- Date Created:
- 2015
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Presentation
- Title:
- Beyond an Apple a Day: Finding Reliable Health Information Online
- Description:
- This collection covers a presentation, handout, and pre- and post- questionnaires to a senior group on finding reliable health information online.
- Keyword:
- KidsHealth, MedlinePlus, health information online, NIH Senior Health, consumer health, senior health
- Subject: MESH:
- Consumer Health Information, Health Education, MedlinePlus, Online Systems, Aged, Child
- Subject: Name:
- National Institutes of Health (U.S.)
- Creator:
- Almader-Douglas, Diana, Gutzman, Karen E
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2015-03-04
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Programmed Instruction
- Title:
- Impactful Visualizations of Bibliographic Metadata in Cardiovascular Disease Epidemiology
- Description:
- Poster presented at the Medical Library Association Annual Conference in May 2015, Austin, TX.
- Abstract:
- This study was requested by an awards committee to investigate the work of an eminent researcher and clinician in cardiovascular disease epidemiology. The committee wanted to highlight the scholar’s career achievements, significant contributions to the scholarly literature, and to demonstrate the scholar’s collaboration with and mentoring of others in this field. Metadata was harvested from open and commercial data aggregators including Scopus, PubMed, Web of Science, various online sources, and the scholar’s CV. A wide range of tools and resources, such as Tableau, Excel, the Sci2 tool, and Adobe Illustrator, were used to visualize the data. Visualizations were chosen based on their ease of understanding, relevance to the committee’s request, and overall visually appealing nature. The visualizations were presented in PowerPoint to the committee at the end of the project.
- Keyword:
- research evaluation, research assessment, research impact, bibliographic metadata, bibliometrics, Medical Library Association. Annual Conference (2015 : Austin, Tex.)
- Subject: MESH:
- Bibliometrics, Research, Evaluation Studies as Topic, Cardiovascular Diseases--epidemiology
- Subject: LCSH:
- Visual analytics, Information visualization
- Creator:
- Gutzman, Karen E, Holmes, Kristi
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Austin, Texas, United States
- Language:
- English
- Date Created:
- 2015-05-16
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Poster
- Title:
- Exploring the History of Medicine, Or five thousand years of medical history in five years, 2012. Part V
- Description:
- Part 5 of a 5 part seminar offered as an elective to the Feinberg School of Medicine M1 and M2 classes.
- Abstract:
- A brief history of medicine in the nineteenth century, and early twentieth century.
- Keyword:
- Elective, Feinberg School of Medicine, Curriculum, History of medicine, Northwestern University (Evanston, Ill). Woman's Medical School
- Subject: MESH:
- History of Medicine, Education, Medical, History, 19th Century, History, 20th Century
- Creator:
- Sims, Ronald H
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2012
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Presentation
- Title:
- Exploring the History of Medicine, Or five thousand years of medical history in five weeks, 2012. Part IV
- Description:
- Part 4 of a 5 part seminar offered as an elective to the Feinberg School of Medicine M1 and M2 classes.
- Abstract:
- A brief history of medicine in the late 17th century, and the eighteenth century.
- Keyword:
- Curriculum, Feinberg School of Medicine, Elective, History of medicine
- Subject: MESH:
- History of Medicine, History, 17th Century, History, 18th Century, Education, Medical
- Creator:
- Sims, Ronald H
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2012
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Presentation
- Title:
- Exploring the History of Medicine, Or five thousand years of medical history in five weeks, 2012. Part III
- Description:
- Part 3 of a 5 part seminar offered as an elective to the Feinberg School of Medicine M1 and M2 classes.
- Abstract:
- A brief history of medicine in the late 16th century and the 17th century.
- Keyword:
- Curriculum, Feinberg School of Medicine, Elective, History of medicine
- Subject: MESH:
- History of Medicine, History, 16th Century, History, 17th Century, Anatomy--history, Microscopy--history, Education, Medical
- Creator:
- Sims, Ronald H
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2012
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Presentation
- Title:
- Exploring the History of Medicine, Or five thousand years of medical history in five weeks, 2012. Part II
- Description:
- Part 2 of a 5 part seminar offered as an elective to the Feinberg School of Medicine M1 and M2 classes.
- Abstract:
- A brief history of medicine in the 16th century.
- Keyword:
- Curriculum, Elective, History of Medicine, Feinberg School of Medicine
- Subject: MESH:
- History of Medicine, History, 16th Century, Education, Medical
- Creator:
- Sims, Ronald H
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2012
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Presentation
- Title:
- Exploring the History of Medicine, Or exploring five thousand years of medical history in five weeks, 2012. Part I
- Description:
- Part 1 of a 5 part seminar offered as an elective to the Feinberg School of Medicine M1 and M2 classes in 2012.
- Abstract:
- The topics covered in this presentation were: a brief history of the Northwestern University Galter Health Sciences Library, and its predecessors, the Northwestern University Medical School and Dental School libraries, including a brief introduction to the resources in their special collections; and the history of Greek, Roman, Persian, Islamic, Jewish, and Medieval medicine from 470 BCE to 1500 CE.
- Keyword:
- History of Medicine, Elective, Curriculum, Feinberg School of Medicine, Galter Health Sciences Library
- Subject: MESH:
- History of Medicine, History, Ancient, History, Medieval, History, 15th Century, Education, Medical
- Subject: Geographic Name:
- Chicago (Ill.)
- Subject: Name:
- Northwestern University (Evanston, Ill.). Medical School. Library, Northwestern University (Evanston, Ill.). Dental School. Library
- Creator:
- Sims, Ronald H
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2012
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Presentation
- Title:
- Pictorial History of Northwestern University's Medical Schools
- Description:
- Presentation at the 8th Chicago Area Medical Archivists (CAMA) medical history symposium, October 27, 2010, Pritzker Auditorium, Northwestern Memorial Hospital 251 E. Huron Street, 3rd floor, Chicago, IL.
- Original Bibliographic Citation:
- Sims, Ronald H., Pictorial History of Northwestern University's Medical Schools [presentation], October 27, 2010, Chicago, IL.
- Abstract:
- Through images and photographs, this presentation provides highlights in the historical timeline of Northwestern University's medical schools that evolved into the present-day Feinberg School of Medicine.
- Keyword:
- Northwestern University Medical School, Chicago AreaMedical Archivists. Medical History Symposium (2010 : Northwestern Memorial Hospital)
- Subject: MESH:
- Schools, Medical--history, History of Medicine
- Subject: Geographic Name:
- Chicago (Ill.)
- Subject: Name:
- Northwestern University (Evanston, Ill.). Medical School, Feinberg School of Medicine, Lind University. Medical Department, Chicago Medical College
- Creator:
- Sims, Ronald H
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2010
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Presentation
- Title:
- Pictorial History of Dermatology at Northwestern University (A)
- Description:
- Presentation to Northwestern University Feinberg School of Medicine Dermatology Department faculty and residents, Northwestern University, July 2010, Chicago, IL.
- Original Bibliographic Citation:
- Sims, Ronald H. Pictorial History of Dermatology at Northwestern University [presentation], July 2010, Chicago, IL.
- Keyword:
- Dermatology, Galter Health Sciences Library
- Subject: MESH:
- Dermatology--history, History of Medicine, Schools, Medical
- Subject: Name:
- Northwestern University (Evanston, Ill.). Medical School
- Creator:
- Sims, Ronald H
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2010
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Presentation
- Title:
- Ophthalmic Treasures from the Galter Health Sciences Library Special Collections at Northwestern University, Chicago, Illinois
- Description:
- Presentation at the Cogan Ophthalmic History Society, 23rd Annual Meeting, April 16-20, 2010, Chicago, IL. An introduction to an exhibit of historical ophthalmologic books and other items from the Galter Library's Special Collections displayed at the meeting venue.
- Original Bibliographic Citation:
- Sims, Ronald H. Ophthalmic Treasures from the Galter Health Sciences Library Special Collections at Northwestern University, Chicago, Illinois. [presented at the Cogan Ophthalmic History Society, 23rd Annual Meeting, April 16-20, 2010, Chicago, IL]
- Keyword:
- Ophthalmology, Rare books, Artifacts, Galter Health Sciences Library
- Subject: MESH:
- Ophthalmology--history, Rare Books--history
- Creator:
- Sims, Ronald H
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2010
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Presentation
- Title:
- Core Informatics Competencies for Clinical and Translational Scientists: What do our customers and collaborators need to know?
- Description:
- Preprint version.
- Abstract:
- Since the inception of the Clinical and Translational Science Award (CTSA) program in 2006, leaders in education across CTSA sites have been developing and updating core competencies for Clinical and Translational Science (CTS) trainees. By 2009, 14 competency domains, including Biomedical Informatics, had been identified and published. Since that time, the evolution of the CTSA program, changes in the practice of CTS, the rapid adoption of electronic health records (EHRs), the growth of biomedical informatics, the explosion of big data, and the realization that some of the competencies had proven to be difficult to apply in practiceall made it clear that the competencies should be updated. This paper describes the process undertaken and puts forth a new set of competencies that has been recently endorsed by the Clinical Research Informatics Workgroup (CRI-WG) of AMIA. In addition to providing context and background for the current version of the competencies, we hope this will serve as a model for revision of competencies over time.
- Keyword:
- competencies, translational informatics
- Subject: MESH:
- Medical Informatics--education, Competency-Based Education, Translational Research, Biomedical--education, Clinical Competence
- Creator:
- Starren, Justin B
- Contributor:
- Valenta, Annette, Meagher, Emma, Tachinardi, Umberto
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2014
- Rights:
- http://creativecommons.org/licenses/by-sa/3.0/us/
- Resource Type:
- Journal Article
- Title:
- Daniel Hale Williams, Surgeon, Educator & Medical Advocate
- Description:
- Galter Health Sciences Library's poster featured as an adjunct to the U.S. National Library of Medicine's traveling exhibit, Opening Doors: Contemporary African American Academic Surgeons. [on display at Northwestern University, Feinberg School of Medicine, Lurie Medical Research Building and Galter Pavilion atrium of Northwestern Memorial Hospital, Chicago, IL from March-April, 2008].
- Abstract:
- Daniel Hale Williams, MD was Northwestern Universitys first African American medical school graduate. He was one of the founders of Provident Hospital on Chicago's south side. He performed the first open heart surgery. He was Surgeon-in-Chief at the Freedman's Hospital in Washington, D.C., Professor of Clinical Surgery at Meharry Medical College, and a surgeon at St. Luke's Hospital in Chicago, Ill. He was a founder of the National Medical Association.
- Keyword:
- Surgery, Hospitals, African Americans, Northwestern University Medical School, alumnus
- Subject: MESH:
- Black or African American, Surgeons, Academic Medical Centers--history, History of Medicine
- Subject: Geographic Name:
- Chicago (Ill.)
- Subject: Name:
- Williams, Daniel Hale, 1856-1931, Northwestern University (Evanston, Ill,). Medical School, Provident Hospital (Chicago, Ill.)
- Creator:
- Sims, Ronald H
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2008
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Biography
- Title:
- Envisaging Biomedicine: Visualization of the Clinical and Scholarly Ecosystem using Bibliographic Metadata
- Description:
- Poster presentation at the Workshop on Visual Analytics in Healthcare, November 15, 2014 held in Washington, D.C.
- Abstract:
- The ability to understand the real impact of research and clinical activities in the modern biomedical academic environment is a Sisyphean task, given the increasing complexity of today’s research and clinical care landscape. The sheer amount of relevant, related data from commercial and open data aggregators, as well as from the enterprise itself in systems such as the EHR, data warehouse, and research information systems, has never been greater. The scholarly publishing process is obviously a very important step of disseminating scholarly discoveries to the broader community. This bibliographic metadata can also play a valuable role in helping an institution gain insights about its research and clinical activities that might not be discernable from other means, including some of the available institution-level data stores. These insights allow both investigators and the institutions themselves to convey the benefits and impact of their research and clinical efforts to stakeholders, thus providing valuable information that can be used for benchmarking, forecasting, and strategic planning activities.
- Keyword:
- data visualization, bibliographic metadata, research impact, Weill Cornell Medical College, Workshop on Visual Analytics in Healthcare (2014 : Washington, D.C.)
- Subject: MESH:
- Data Display, Research, Bibliometrics
- Subject: LCSH:
- Visual analytics
- Creator:
- Gutzman, Karen E, Holmes, Kristi, Bales, Michael, Albert, Paul, Wheeler, Terrie R.
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2014-11-14
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Poster
- Title:
- The Kaleidoscope of Impact: same data, different perspectives, constantly changing
- Description:
- Presentation for Advancing Research Communication and Scholarship (ARCS) Conference 2015 in Philadelphia, PA. Presented on 04/28/2015. Slides were altered from this format to fit the group presentation (see Related URL: slideshare)
- Abstract:
- Scholars, scientists, academic institutions, publishers and funders are all interested in impact. We have different roles and goals, and therefore different reasons for needing to understand impact; we are therefore asking different questions about impact, and those questions continue to evolve, much as the concept of impact itself is evolving. To answer our different questions, do we need different data, in separate silos, or are we looking at the same data, from different angles? This session gathered researcher, library, publisher and metrics provider perspectives to consider who has an interest in impact, what data they are interested in, how they use it, and how the situation is evolving as e.g. business models and technical infrastructures shift.
- Keyword:
- research impact, research evaluation, Advancing Research Communication and Scholarship Conference (2015 : Philadelphia, Pa.), ARCS Conference
- Subject: MESH:
- Research, Bibliometrics, Evaluation Studies as Topic
- Subject: LCSH:
- Research--Evaluation
- Creator:
- Gutzman, Karen E
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Philadelphia, Pennsylvania, United States
- Language:
- English
- Date Created:
- 2015-04-24
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Presentation
- Title:
- A Library Evolving: providing research impact and evaluation services
- Description:
- Poster presented at the American Evaluation Association Annual International Conference, Chicago, IL 2015. Presented on 11/11/2015.
- Abstract:
- In early 2014, Northwestern University’s Galter Library began implementing a cohesive set of services around research evaluation and impact assessment, formally structured in the library as the Metrics and Impact Core (MIC). Many of the MIC services utilize the library’s expertise in bibliographic data, which can be mined, analyzed and visualized using a variety of techniques to gain a better understanding research impact. This poster will discuss the operationalization of these services from the standpoint of a modern medical library and present the partnerships, resources and tools needed to make this vision a reality. We will discuss the types of reports and activities we’ve developed to suit the needs of our stakeholders using bibliographic data, and the challenges and successes we’ve found along the way.
- Keyword:
- research impact, research assessment, library services, research evaluation, American Evaluation Association
- Subject: MESH:
- Bibliometrics
- Creator:
- Gutzman, Karen E
- Contributor:
- Holmes, Kristi
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2015-11-03
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Poster
6422. The Road to Making Patient-Centered Care Real : Policy Vehicles and Potholes : research report
- Title:
- The Road to Making Patient-Centered Care Real : Policy Vehicles and Potholes : research report
- Abstract:
- This report examines the origins of the term "patient-centered care" and its current meaning; reviews laws that have been important vehicles for moving patient-centeredness from ideal to real; reviews some of the measurement tools and research involved in enabling patient-centeredness to become operational as well as aspirational; and examines the obstacles that can obstruct progress and implementation of patient-centered care.
- Keyword:
- patient-centered care, patient engagement, health policy, patient-generated health data, Triple Aim
- Subject: MESH:
- Patient-Centered Care, Health Policy
- Creator:
- Millenson, Michael, Berenson, Robert A.
- Publisher:
- Urban Institute, DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2015
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Report
- Title:
- Comparison of range-of-motion and variability in upper body movements between transradial prosthesis users and able-bodied controls when executing goal-oriented tasks
- Original Bibliographic Citation:
- Major MJ, Stine RL, Heckathorne CW, Fatone S, Gard SA. (2014) Comparison of range-of-motion and variability in upper body movements between transradial prosthesis users and able-bodied controls when executing goal-oriented tasks. J Neuroeng Rehabil. 11:132.
- Abstract:
- Current upper limb prostheses do not replace the active degrees-of-freedom distal to the elbow inherent to intact physiology. Limited evidence suggests that transradial prosthesis users demonstrate shoulder and trunk movements to compensate for these missing volitional degrees-of-freedom. The purpose of this study was to enhance understanding of the effects of prosthesis use on motor performance by comparing the movement quality of upper body kinematics between transradial prosthesis users and able-bodied controls when executing goal-oriented tasks that reflect activities of daily living.
- Keyword:
- Upper limbs, Transradial amputation, Kinematics, Trunk, Prosthesis
- Subject: MESH:
- Activities of Daily Living, Artificial Limbs, Biomechanical Phenomena, Movement--physiology, Range of Motion, Articular, Upper Extremity--physiology
- Creator:
- Major, Matthew Justin, Stine, Rebecca, Heckathorne, Craig W, Fatone, Stefania, Gard, Steven A
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2014
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Journal Article
- Title:
- Woman's Medical School at Northwestern University, 1870-1902 (3)
- Description:
- Third of a series of Galter Health Sciences Library posters featured as an adjunct to the U.S. National Library of Medicine's traveling exhibit, Changing the face of Medicine - Celebrating America's Women Physicians. [on display at Northwestern University, Feinberg School of Medicine, Lurie Medical Research Building, Chicago, IL from December 9, 2009-January 3, 2010]., The exhibit was organized by the National Library of Medicine and was sponsored by the Galter Health Sciences Library, the Institute for WomensHealth Research and the Northwestern Medical Women Faculty Organization. Sponsoring units presented posters during the exhibit demonstrating how women have changed the face of medicine at Northwestern. In addition, a panel of notable Northwestern women discussed their contributions to medicine and health care in the areasof research, education, and clinical care in Hughes Auditorium on December 7, 2009 at 3:00PM. The panel members were: Neena B. Schwartz, PhD, Teresa W. Woodruff, PhD, Erica Marsh, MD, MSCI, and Candace Tingen, BS, BA. A reception followed at 4:30PM.
- Original Bibliographic Citation:
- Sims, R. Woman's Medical School at Northwestern, 1870-1902 (3). Poster presented as adjunct to the NLM traveling exhibit, Changing the face of Medicine - Celebrating America's Women Physicians, December 2009-January 2010, Chicago, IL.
- Abstract:
- The traveling exhibit describes the remarkable progress women have made in professional training, achieving diversity and providing leadership in health care. Changing the Face of Medicine: Celebrating America’s Women Physicians begins with Elizabeth Blackwell, the first woman to earn an M.D. degree in America in 1849, and ends with women physicians today, who have achieved success in work once considered "unsuitable" for a woman.
- Keyword:
- Northwestern University Woman's Medical School
- Subject: MESH:
- Students, Medical--history, Schools, Medical, History of Medicine, Physicians, Women
- Subject: Geographic Name:
- Chicago (Ill.)
- Subject: Name:
- Northwestern University (Evanston, Ill.). Woman's Medical School
- Creator:
- Sims, Ronald H
- Contributor:
- Northwestern University (Evanston, Ill.). Women's Health Research Institute, Northwestern Medical Women Faculty Organization, Galter Health Sciences Library
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Page Number:
- 3
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2009
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Exhibitions
- Title:
- Woman's Medical School at Northwestern University, 1870-1902 (2)
- Description:
- Second of a series of Galter Health Sciences Library posters featured as an adjunct to the U.S. National Library of Medicine's traveling exhibit, Changing the face of Medicine - Celebrating America's Women Physicians. [on display at Northwestern University, Feinberg School of Medicine, Lurie Medical Research Building, Chicago, IL from December 9, 2009-January 3, 2010]., The exhibit was organized by the National Library of Medicine and was sponsored by the Galter Health Sciences Library, the Institute for Womens Health Research and the Northwestern Medical Women Faculty Organization. Sponsoring units presented posters during the exhibit demonstrating how women have changed the face of medicine at Northwestern. In addition, a panel of notable Northwestern women discussed their contributions to medicine and health care in the areas of research, education, and clinical care in Hughes Auditorium on December 7, 2009 at 3:00PM. The panel members were: Neena B. Schwartz, PhD, Teresa W. Woodruff, PhD, Erica Marsh, MD, MSCI, and Candace Tingen, BS, BA. A reception followed at 4:30PM.
- Original Bibliographic Citation:
- Sims, R. Woman's Medical School at Northwestern, 1870-1902 (2). Poster presented as adjunct to the NLM traveling exhibit, Changing the face of Medicine - Celebrating America's Women Physicians, December 2009-January 2010, Chicago, IL.
- Abstract:
- The traveling exhibit describes the remarkable progress women have made in professional training, achieving diversity and providing leadership in health care. Changing the Face of Medicine: Celebrating America’s Women Physicians begins with Elizabeth Blackwell, the first woman to earn an M.D. degree in America in 1849, and ends with women physicians today, who have achieved success in work once considered "unsuitable" for a woman.
- Keyword:
- Northwestern University Women's Medical School
- Subject: MESH:
- Schools, Medical--history, Students, Medical, History of Medicine, Physicians, Women
- Subject: Geographic Name:
- Chicago (Ill.)
- Subject: Name:
- Northwestern University (Evanston, Ill.). Woman's Medical School
- Creator:
- Sims, Ronald H
- Contributor:
- Northwestern University (Evanston, Ill.). Women's Health Research Institute, Northwestern Medical Women Faculty Organization, Galter Health Sciences Library
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Page Number:
- 2
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2009
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Exhibitions
- Title:
- Woman's Medical School at Northwestern University, 1870-1902 (1)
- Description:
- First of a series of Galter Health Sciences Library posters featured as an adjunct to the U.S. National Library of Medicine's traveling exhibit, Changing the face of Medicine - Celebrating America's Women Physicians. [on display at Northwestern University, Feinberg School of Medicine, Lurie Medical Research Building, Chicago, IL from December 9, 2009-January 3, 2010]. The exhibit was organized by the National Library of Medicine and was sponsored by the Galter Health Sciences Library, the Institute for Womens Health Research and the Northwestern Medical Women Faculty Organization. Sponsoring units presented posters during the exhibit demonstrating how women have changed the face of medicine at Northwestern. In addition, a panel of notable Northwestern women discussed their contributions to medicine and health care in the areas of research, education, and clinical care in Hughes Auditorium on December 7, 2009 at 3:00PM. The panel members were: Neena B. Schwartz, PhD, Teresa W. Woodruff, PhD, Erica Marsh, MD, MSCI, and Candace Tingen, BS, BA. A reception followed at 4:30PM.
- Original Bibliographic Citation:
- Sims, R. Woman's Medical School at Northwestern, 1870-1902 (1). Poster presented as adjunct to the NLM traveling exhibit, Changing the face of Medicine - Celebrating America's Women Physicians, December 2009-January 2010, Chicago, IL.
- Abstract:
- The traveling exhibit describes the remarkable progress women have made in professional training, achieving diversity and providing leadership in health care. Changing the Face of Medicine: Celebrating America’s Women Physicians begins with Elizabeth Blackwell, the first woman to earn an M.D. degree in America in 1849, and ends with women physicians today, who have achieved success in work once considered "unsuitable" for a woman.
- Keyword:
- Northwestern University Women's Medical School
- Subject: MESH:
- Schools, Medical--history, Students, Medical, History of Medicine, Physicians, Women
- Subject: Geographic Name:
- Chicago (Ill.)
- Subject: Name:
- Northwestern University (Evanston, Ill.). Woman's Medical School
- Creator:
- Sims, Ronald H
- Contributor:
- Northwestern University (Evanston, Ill.). Women's Health Research Institute, Northwestern Medical Women Faculty Organization, Galter Health Sciences Library
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Page Number:
- 1
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2009
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Exhibitions
- Title:
- Ephus: multipurpose data acquisition software for neuroscience experiments
- Original Bibliographic Citation:
- Suter BA, O'Connor T, Iyer V, Petreanu LT, Hooks BM, Kiritani T, Svoboda K, Shepherd GM. (2010) Ephus: multipurpose data acquisition software for neuroscience experiments. Front Neural Circuits 4:100.
- Abstract:
- Physiological measurements in neuroscience experiments often involve complex stimulus paradigms and multiple data channels. Ephus (http://www.ephus.org) is an open-source software package designed for general-purpose data acquisition and instrument control. Ephus operates as a collection of modular programs, including an ephys program for standard whole-cell recording with single or multiple electrodes in typical electrophysiological experiments, and a mapper program for synaptic circuit mapping experiments involving laser scanning photostimulation based on glutamate uncaging or channelrhodopsin-2 excitation. Custom user functions allow user-extensibility at multiple levels, including on-line analysis and closed-loop experiments, where experimental parameters can be changed based on recently acquired data, such as during in vivo behavioral experiments. Ephus is compatible with a variety of data acquisition and imaging hardware. This paper describes the main features and modules of Ephus and their use in representative experimental applications.
- Keyword:
- Neuroscience, Neocortex, Software, Data
- Subject: MESH:
- Neurosciences--methods, Electrophysiology--instrumentation, Software, Data Collection, Information Storage and Retrieval
- Creator:
- Suter, Benjamin, Shepherd, Gordon M G, O'Connor, Timothy, Kiritani, Taro
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2010
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Journal Article
- Original Identifier:
- (PMID)21960959
- Title:
- Neurophotonics applications to motor cortex research: a review
- Original Bibliographic Citation:
- Suter BA, Yamawaki N, Borges K, Li X, Kiritani T, Hooks BM, Shepherd GM. (2014) Neurophotonics applications to motor cortex research: a review. Neurophotonics 1(1)
- Abstract:
- Neurophotonics methods offer powerful ways to access neuronal signals and circuits. We highlight recent advances and current themes in this area, emphasizing tools for mapping, monitoring, and manipulating excitatory projection neurons and their synaptic circuits in mouse motor cortex.
- Keyword:
- Neuroscience, Neocortex
- Subject: MESH:
- Optics and Photonics, Optogenetics, Motor Cortex, Pyramidal Cells, Mice, Neural Pathways
- Creator:
- Suter, Benjamin, Shepherd, Gordon M G, Yamawaki, Naoki, Borges, Katharine Ellen Munckton, Li, Xiaojian, Kiritani, Taro
- Publisher:
- SPIE, DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2014
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Review
- Original Identifier:
- (PMID)25553337
- Title:
- Intrinsic Electrophysiology of Mouse Corticospinal Neurons: a Class-Specific Triad of Spike-Related Properties
- Original Bibliographic Citation:
- Suter, Benjamin A., Migliore, Michele, Shepherd, Gordon M G. (2013) Intrinsic Electrophysiology of Mouse Corticospinal Neurons: a Class-Specific Triad of Spike-Related Properties. Cereb Cortex. 23(8):1965-1977.
- Abstract:
- Corticospinal pyramidal neurons mediate diverse aspects of motor behavior. We measured spike-related electrophysiological properties of identified corticospinal neurons in primary motor cortex slices from young adult mice. Several consistent features were observed in the suprathreshold responses to current steps: 1) Corticospinal neurons fired relatively fast action potentials (APs; width at half-maximum 0.65 0.13 ms, mean standard deviation [SD]) compared with neighboring callosally projecting corticostriatal neurons. Corticospinal AP width was intermediate between 2 classes of inhibitory interneuron in layer 5B. Spike-to-spike variability in AP width and other spike waveform parameters was low, even during repetitive firing up to 20 Hz, that is, the relative narrowness of corticospinal APs was essentially frequency independent. 2) Frequency-current (f-I) relationships were nearly linear. 3) Trains of APs displayed regular firing, with rates typically staying constant or accelerating over time. Corticospinal neurons recorded from older mice (up to 4 months) or from a separate lateral cortical area (Region B; corresponding to secondary somatosensory cortex) showed generally similar intrinsic properties. Our findings have implications for interpreting spike waveforms of in vivo recorded neurons in the motor cortex. This analysis provides a framework for further biophysical and computational investigations of corticospinal neurons and their roles in motor cortical function.
- Keyword:
- Neuroscience, Neocortex
- Subject: MESH:
- Action Potentials, Interneurons, Mice, Inbred C57BL, Motor Cortex, Pyramidal Tracts, Pyramidal Cells
- Creator:
- Suter, Benjamin, Shepherd, Gordon M G, Migliore, Michele
- Publisher:
- Oxford University Press, DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2012
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Journal Article
- Original Identifier:
- (PMID)22761308
6430. Toward an integrated approach to perception and action: conference report and future directions
- Title:
- Toward an integrated approach to perception and action: conference report and future directions
- Original Bibliographic Citation:
- Gordon G, Kaplan DM, Lankow B, Little DY, Sherwin J, Suter BA, Thaler L. (2011) Toward an integrated approach to perception and action: conference report and future directions. Front Syst Neurosci. 5:20.
- Abstract:
- This article was motivated by the conference entitled "Perception & Action - An Interdisciplinary Approach to Cognitive Systems Theory," which took place September 14-16, 2010 at the Santa Fe Institute, NM, USA. The goal of the conference was to bring together an interdisciplinary group of neuroscientists, roboticists, and theorists to discuss the extent and implications of action-perception integration in the brain. The motivation for the conference was the realization that it is a widespread approach in biological, theoretical, and computational neuroscience to investigate sensory and motor function of the brain in isolation from one another, while at the same time, it is generally appreciated that sensory and motor processing cannot be fully separated. Our article summarizes the key findings of the conference, provides a hypothetical model that integrates the major themes and concepts presented at the conference, and concludes with a perspective on future challenges in the field.
- Keyword:
- Neuroscience, Neocortex
- Subject: MESH:
- Perception--physiology, Sensorimotor Cortex--physiology, Sensation--physiology, Models, Neurological, Movement--physiology, Robotics, Brain--physiology
- Creator:
- Suter, Benjamin
- Publisher:
- Frontiers Media, DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2011
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Journal Article
- Original Identifier:
- (PMID)21541257
- Title:
- Reciprocal Interareal Connections to Corticospinal Neurons in Mouse M1 and S2
- Original Bibliographic Citation:
- Suter, Benjamin A., Shepherd, Gordon M.G. (2015) Reciprocal Interareal Connections to Corticospinal Neurons in Mouse M1 and S2. J Neurosci 35:2959-2974.
- Abstract:
- Primary motor (M1) and secondary somatosensory (S2) cortices, although anatomically and functionally distinct, share an intriguing cellular component: corticospinal neurons (CSP) in layer 5B. Here, we investigated the long-range circuits of CSPs in mouse forelimb-M1 and S2. We found that interareal projections (S2 M1 and M1 S2) monosynaptically excited pyramidal neurons across multiple layers, including CSPs. Area-specific differences were observed in the relative strengths of inputs to subsets of CSPs and other cell types, but the general patterns were similar. Furthermore, subcellular mapping of the dendritic distributions of these corticocortical excitatory synapses onto CSPs in both areas also showed similar patterns. Because layer 5B is particularly thick in M1, but not S2, we studied M1-CSPs at different cortical depths, quantifying their dendritic morphology and mapping inputs from additional cortical (M2, contralateral M1, and local layer 2/3) and thalamic (VL nucleus) sources. These results indicated that CSPs exhibit area-specific modifications on an otherwise conserved synaptic organization, and that different afferents innervate M1-CSP dendritic domains in a source-specific manner. In the cervical spinal cord, CSP axons from S2 and M1 partly converged on middle layers, but S2-CSP axons extended further dorsally, and M1-CSP axons ventrally. Thus, our findings identify many shared features in the circuits of M1 and S2 and show that these areas communicate via mutual projections that give each area monosynaptic access to the other area's CSPs. These interareally yoked CSP circuits may enable M1 and S2 to operate in a coordinated yet differentiated manner in the service of sensorimotor integration.
- Keyword:
- Neuroscience, Neocortex
- Subject: MESH:
- Brain Mapping, Luminescent Proteins, Mice, Inbred C57BL, Mice, Transgenic, Motor Cortex, Neural Pathways, Pyramidal Tracts, Somatosensory Cortex, Synapses, Thalamus
- Creator:
- Suter, Benjamin, Shepherd, Gordon M. G.
- Publisher:
- The Journal of Neuroscience, DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2015
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Journal Article
- Original Identifier:
- (PMID)25698734
- Title:
- A genuine layer 4 in motor cortex with prototypical synaptic circuit connectivity
- Original Bibliographic Citation:
- Chadderdon GL, Mohan A, Suter BA, Neymotin SA, Kerr CC, Francis JT, Shepherd GM, Lytton WW. (2014) Neural Comput. 26(7):1239-1262.
- Abstract:
- The motor cortex (M1) is classically considered an agranular area, lacking a distinct layer 4 (L4). Here, we tested the idea that M1, despite lacking a cytoarchitecturally visible L4, nevertheless possesses its equivalent in the form of excitatory neurons with inputoutput circuits like those of the L4 neurons in sensory areas. Consistent with this idea, we found that neurons located in a thin laminar zone at the L3/5A border in the forelimb area of mouse M1 have multiple L4-like synaptic connections: excitatory input from thalamus, largely unidirectional excitatory outputs to L2/3 pyramidal neurons, and relatively weak long-range corticocortical inputs and outputs. M1-L4 neurons were electrophysiologically diverse but morphologically uniform, with pyramidal-type dendritic arbors and locally ramifying axons, including branches extending into L2/3. Our findings therefore identify pyramidal neurons in M1 with the expected prototypical circuit properties of excitatory L4 neurons, and question the traditional assumption that motor cortex lacks this layer.
- Keyword:
- Neuroscience, Neocortex
- Subject: MESH:
- Action Potentials, Adenoviridae--genetics, Axons, Dendrites, Genetic Vectors, Mice, Motor Cortex, Pyramidal Cells, Synapses, Synaptic Potentials, Synaptic Transmission, Thalamus--physiology
- Creator:
- Suter, Benjamin, Shepherd, Gordon M G, Yamawaki, Naoki, Borges, Katharine Ellen Munckton
- Publisher:
- eLife, DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2014
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Journal Article
- Original Identifier:
- (PMID)25525751
- Title:
- Reduction of thalamic and cortical Ih by deletion of TRIP8b produces a mouse model of human absence epilepsy
- Original Bibliographic Citation:
- Heuermann RJ, Jaramillo TC, Ying SW, Suter BA, Lyman KA, Han Y, Lewis AS, Hampton TG, Shepherd GM, Goldstein PA, Chetkovich DM. (2016) Reduction of thalamic and cortical Ih by deletion of TRIP8b produces a mouse model of human absence epilepsy. Neurobiol Dis 85:81-92.
- Abstract:
- Absence seizures occur in several types of human epilepsy and result from widespread, synchronous feedback between the cortex and thalamus that produces brief episodes of loss of consciousness. Genetic rodent models have been invaluable for investigating the pathophysiological basis of these seizures. Here, we identify tetratricopeptide-containing Rab8b-interacting protein (TRIP8b) knockout mice as a new model of absence epilepsy, featuring spontaneous spike-wave discharges on electroencephalography (EEG) that are the electrographic hallmark of absence seizures. TRIP8b is an auxiliary subunit of the hyperpolarization-activated cyclic-nucleotide-gated (HCN) channels, which have previously been implicated in the pathogenesis of absence seizures. In contrast to mice lacking the pore-forming HCN channel subunit HCN2, TRIP8b knockout mice exhibited normal cardiac and motor function and a less severe seizure phenotype. Evaluating the circuit that underlies absence seizures, we found that TRIP8b knockout mice had significantly reduced HCN channel expression and function in thalamic-projecting cortical layer 5b neurons and thalamic relay neurons, but preserved function in inhibitory neurons of the reticular thalamic nucleus. Our results expand the known roles of TRIP8b and provide new insight into the region-specific functions of TRIP8b and HCN channels in constraining cortico-thalamo-cortical excitability.
- Keyword:
- Neuroscience, Neocortex, Trip8b protein, mouse
- Subject: MESH:
- Neocortex, Epilepsy, Absence, Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels, Models, Animal, Models, Neurological, Thalamus, Electroencephalography, Neural Pathways
- Creator:
- Suter, Benjamin, Chetkovich, Dane M, Heuerman, Robert J, Jaramillo, Thomas C, Lyman, Kyle A, Lewis, Alan S, Han, Ye, Shepherd, Gordon M G
- Publisher:
- Elsevier, DigitalHub. Galter Health Sciences Library
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Journal Article
- Original Identifier:
- (PMID)26459112
- Title:
- Cell-Specific Activity-Dependent Fractionation of Layer 2/35->5B Excitatory Signaling in Mouse Auditory Cortex
- Original Bibliographic Citation:
- Joshi A, Middleton JW, Anderson CT, Borges K, Suter BA, Shepherd GM, Tzounopoulos T. (2015) Cell-Specific Activity-Dependent Fractionation of Layer 2/35B Excitatory Signaling in Mouse Auditory Cortex. J Neurosci 35(7):3112-3123
- Abstract:
- Auditory cortex (AC) layer 5B (L5B) contains both corticocollicular neurons, a type of pyramidal-tract neuron projecting to the inferior colliculus, and corticocallosal neurons, a type of intratelencephalic neuron projecting to contralateral AC. Although it is known that these neuronal types have distinct roles in auditory processing and different response properties to sound, the synaptic and intrinsic mechanisms shaping their input-output functions remain less understood. Here, we recorded in brain slices of mouse AC from retrogradely labeled corticocollicular and neighboring corticocallosal neurons in L5B. Corticocollicular neurons had, on average, lower input resistance, greater hyperpolarization-activated current (Ih), depolarized resting membrane potential, faster action potentials, initial spike doublets, and less spike-frequency adaptation. In paired recordings between single L2/3 and labeled L5B neurons, the probabilities of connection, amplitude, latency, rise time, and decay time constant of the unitary EPSC were not different for L2/3corticocollicular and L2/3corticocallosal connections. However, short trains of unitary EPSCs showed no synaptic depression in L2/3corticocollicular connections, but substantial depression in L2/3corticocallosal connections. Synaptic potentials in L2/3corticocollicular connections decayed faster and showed less temporal summation, consistent with increased Ih in corticocollicular neurons, whereas synaptic potentials in L2/3corticocallosal connections showed more temporal summation. Extracellular L2/3 stimulation at two different rates resulted in spiking in L5B neurons; for corticocallosal neurons the spike rate was frequency dependent, but for corticocollicular neurons it was not. Together, these findings identify cell-specific intrinsic and synaptic mechanisms that divide intracortical synaptic excitation from L2/3 to L5B into two functionally distinct pathways with different input-output functions.
- Keyword:
- Neuroscience, Neocortex
- Subject: MESH:
- Auditory Cortex, Auditory Pathways, Mice, Inbred ICR, Excitatory Amino Acid Antagonists, Flavoproteins, GABA Antagonists, Inferior Colliculi, Models, Neurological, Neurons, Patch-Clamp Techniques, Pyridazines, Quinoxalines, Synaptic Potentials, Valine
- Creator:
- Suter, Benjamin, Shepherd, Gordon M G
- Publisher:
- Journal of Neuroscience, DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2014
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Journal Article
- Original Identifier:
- (PMID)25698747
- Title:
- Motor Cortex Microcircuit Simulation Based on Brain Activity Mapping
- Original Bibliographic Citation:
- Chadderdon GL, Mohan A, Suter BA, Neymotin SA, Kerr CC, Francis JT, Shepherd GM, Lytton WW. (2014) Motor Cortex Microcircuit Simulation Based on Brain Activity Mapping. Neural Comput. 26(7):1239-1262.
- Abstract:
- The deceptively simple laminar structure of neocortex belies the complexity of intra- and interlaminar connectivity. We developed a computational model based primarily on a unified set of brain activity mapping studies of mouse M1. The simulation consisted of 775 spiking neurons of 10 cell types with detailed population-to-population connectivity. Static analysis of connectivity with graph-theoretic tools revealed that the corticostriatal population showed strong centrality, suggesting that would provide a network hub. Subsequent dynamical analysis confirmed this observation, in addition to revealing network dynamics that cannot be readily predicted through analysis of the wiring diagram alone. Activation thresholds depended on the stimulated layer. Low stimulation produced transient activation, while stronger activation produced sustained oscillations where the threshold for sustained responses varied by layer: 13% in layer 2/3, 54% in layer 5A, 25% in layer 5B, and 17% in layer 6. The frequency and phase of the resulting oscillation also depended on stimulation layer. By demonstrating the effectiveness of combined static and dynamic analysis, our results show how static brain maps can be related to the results of brain activity mapping.
- Keyword:
- Neuroscience, Neocortex
- Subject: MESH:
- Brain Mapping, Mice, Computer Simulation, Models, Neurological, Motor Cortex, Neural Pathways, Neurons, Periodicity, Synapses
- Creator:
- Suter, Benjamin, Chadderdon, George L, Shepherd, Gordon M G
- Publisher:
- Massachusetts Institute of Technology, DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2013
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Journal Article
- Original Identifier:
- (PMID)24708371
- Title:
- Corticospinal-specific HCN expression in mouse motor cortex: Ih-dependent synaptic integration as a candidate microcircuit mechanism involved in motor control
- Original Bibliographic Citation:
- Sheets PL, Suter BA, Kiritani T, Chan CS, Surmeier DJ, Shepherd GM. (2011) Corticospinal-specific HCN expression in mouse motor cortex: Ih-dependent synaptic integration as a candidate microcircuit mechanism involved in motor control. J Neurophysiol 106(5):2216-2231.
- Abstract:
- Motor cortex is a key brain center involved in motor control in rodents and other mammals, but specific intracortical mechanisms at the microcircuit level are largely unknown. Neuronal expression of hyperpolarization-activated current (I(h)) is cell class specific throughout the nervous system, but in neocortex, where pyramidal neurons are classified in various ways, a systematic pattern of expression has not been identified. We tested whether I(h) is differentially expressed among projection classes of pyramidal neurons in mouse motor cortex. I(h) expression was high in corticospinal neurons and low in corticostriatal and corticocortical neurons, a pattern mirrored by mRNA levels for HCN1 and Trip8b subunits. Optical mapping experiments showed that I(h) attenuated glutamatergic responses evoked across the apical and basal dendritic arbors of corticospinal but not corticostriatal neurons. Due to I(h), corticospinal neurons resonated, with a broad peak at 4 Hz, and were selectively modulated by -adrenergic stimulation. I(h) reduced the summation of short trains of artificial excitatory postsynaptic potentials (EPSPs) injected at the soma, and similar effects were observed for short trains of actual EPSPs evoked from layer 2/3 neurons. I(h) narrowed the coincidence detection window for EPSPs arriving from separate layer 2/3 inputs, indicating that the dampening effect of I(h) extended to spatially disperse inputs. To test the role of corticospinal I(h) in transforming EPSPs into action potentials, we transfected layer 2/3 pyramidal neurons with channelrhodopsin-2 and used rapid photostimulation across multiple sites to synaptically drive spiking activity in postsynaptic neurons. Blocking I(h) increased layer 2/3-driven spiking in corticospinal but not corticostriatal neurons. Our results imply that I(h)-dependent synaptic integration in corticospinal neurons constitutes an intracortical control mechanism, regulating the efficacy with which local activity in motor cortex is transferred to downstream circuits in the spinal cord. We speculate that modulation of I(h) in corticospinal neurons could provide a microcircuit-level mechanism involved in translating action planning into action execution.
- Keyword:
- Neuroscience, Neocortex
- Subject: MESH:
- Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels, Motor Cortex, Mice, Inbred C57BL, Excitatory Postsynaptic Potentials
- Creator:
- Suter, Benjamin, Sheets, Patrick L., Kiritani, Taro, Chan, Savio, Surmeier, Dalton James, Shepherd, Gordon M G
- Publisher:
- American Physiological Society, DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2011
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Journal Article
- Original Identifier:
- (PMID)21795621
- Title:
- Tempering Allorecognition to Induce Transplant Tolerance With Chemically Modified Apoptotic Donor Cells
- Original Bibliographic Citation:
- McCarthy DP, Bryant J, Galvin JP, Miller SD, Luo, X (2015) Tempering Allorecognition to Induce Transplant Tolerance With Chemically Modified Apoptotic Donor Cells. Am J Transplant 15(6):1475-1483.
- Abstract:
- The development of organ transplantation as a therapy for end-stage organ failure is among the most significant achievements of 20th century medicine, but chronic rejection remains a barrier to achieving long-term success. Current therapeutic regimens consist of immunosuppressive drugs that are efficient at delaying rejection but are associated with significant risks such as opportunistic infections, toxicity, and malignancy. Thus, the induction of specific immune tolerance to transplant antigens is the coveted aim of researchers. The use of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (ECDI)-treated, autoantigen-coupled syngeneic leukocytes has been developed as a specific immunotherapy in preclinical models of autoimmunity and is currently in a phase II clinical trial for the treatment of multiple sclerosis. In this review, we discuss the use of allogeneic ECDI-treated apoptotic donor leukocytes (allo-ECDI-SP) as a strategy for inducing antigen-specific tolerance in allogeneic transplantation. Allo-ECDI-SP therapy induces long-term systemic immune tolerance to transplant antigens by subverting alloimmune recognition and exploiting apoptotic cell uptake pathways to recapitulate innate mechanisms of peripheral tolerance. Lastly, we discuss potential indications and challenges for transitioning allo-ECDI-SP therapy into clinical practice.
- Keyword:
- Tolerance, Transplant, Apoptotic cells
- Subject: MESH:
- Transplantation Tolerance, Transplantation Immunology, Transplantation, Homologous, Histocompatibility Antigens
- Creator:
- Galvin, John P, Miller, Stephen D, Luo, Xunrong, McCarthy, D. P., Bryant, J.
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2015
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Review
- Title:
- Apoptosis Induced by Granzyme B-Glycosaminoglycan Complexes: Implications for Granule-Mediated Apoptosis In Vivo
- Original Bibliographic Citation:
- Galvin JP, Spaeny-Dekking LH, Wang B, Seth P, Hack CE, Froelich CJ. (1999) Apoptosis Induced by Granzyme B-Glycosaminoglycan Complexes: Implications for Granule-Mediated Apoptosis In Vivo. J Immunol 162(9):5345-5350.
- Abstract:
- Lymphocyte granule-mediated apoptosis occurs by perforin-mediated intracellular delivery of granule-associated serine proteases (granzymes). A granule-associated proteoglycan, namely serglycin, that contains chondroitin 4-sulfate (CS) glycosaminoglycans is present in the granules of cytotoxic cells. Serglycin acts as scaffold for packaging the positively charged granzymes and probably chaperones the proteases secreted extracellularly. To learn how the interaction of granzyme B (GrB) with serglycin might influence the apoptotic potential of this proteases, we have evaluated a model system where desalted CS is combined with isolated human granzyme. CS-GrB complexes were very stable, remaining undissociated in salt concentrations upwards to 500 mM (pH 7.4). On the basis of a capture enzyme immunoassay that accurately detects GrB, equivalent amounts of active free and CS-GrB, delivered by perforin or adenovirus, efficiently induced apoptosis in Jurkat cells and produced a similar time-dependent increase in caspase-3-like activity. CS-GrB processed isolated caspases-3 and -7 less efficiently than free granzyme. However, when added to cytosolic extracts, rates of processing were nearly equivalent for the two forms, suggesting cationic GrB may nonspecifically bind cytosolic proteins, leading to reduce proteolytic activity. Finally, GrB was found to be exocytosed from lymphocyte-activated killer cells as a neutral, high macromolecular weight complex, which possessed apoptotic activity. Collectively, the results indicate that neutral, high m.w. GrB has the capacity to induce cell death and will be useful to study the mechanism of cytotoxic cell-mediated apoptosis in vitro.
- Keyword:
- Apoptosis, Granzyme
- Subject: MESH:
- Apoptosis, Granzymes, Glycosaminoglycans
- Creator:
- Galvin, John P, Froelich, Christopher J, Wang, Baikun, Spaeny-Dekking, Liesbeth H. A., Seth, Prem K, Hack, C. EriK
- Publisher:
- American Association of Immunologists, Inc., DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 1999
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Journal Article
- Original Identifier:
- (PMID)10228010
- Title:
- Regulation of the kinase RSK1 by arsenic trioxide and generation of antileukemic responses
- Original Bibliographic Citation:
- Galvin JP, Altman JK, Szilard A, Goussetis DJ, Vakana E, Sassano A, Platanias LC. (2013) Cancer Biol Ther 14:411-416.
- Abstract:
- Arsenic Trioxide (AsO) is one of the most effective agents in the treatment of acute promyelocytic leukemia (APL), but has no significant efficacy in other forms of AML. The mechanisms of relative resistance of non-APL cells are not well understood, but emerging evidence suggests that activation of negative feedback regulatory loops and pathways contributes to such resistance. We provide evidence that a signaling cascade involving the kinase RSK1 is engaged in a negative feedback manner during arsenic-treatment of cells and exhibits regulatory effects on growth and survival of AML cells in response to treatment with AsO. Our data demonstrate that pharmacological inhibition or molecular disruption of expression of RSK1 enhances AsO-dependent apoptosis and/or growth inhibition of AML cells. Importantly, combination of a pharmacological inhibitor of RSK and AsO results in enhanced suppression of primary AML leukemic progenitors. Altogether, our findings suggest an important regulatory role for RSK1 in the generation of the effects of AsO in AML cells. They also raise the potential of RSK1 targeting in combination with AsO as a novel approach to promote antileukemic responses.
- Keyword:
- Leukemia, Arsenic Trioxide, RSK1
- Subject: MESH:
- Arsenicals--pharmacology, Leukemia, Myeloid, Acute, Ribosomal Protein S6 Kinases, 90-kDa
- Creator:
- Galvin, John P, Platanias, Leonidas C, Altman, Jessica K, Szilard, Amy, Goussetis, Dennis J., Vakana, Eliza, Sassano, Antonella
- Publisher:
- Landes Bioscience, DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2013
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Journal Article
- Original Identifier:
- (PMID)23377826
- Title:
- When You Come to a Fork in the Road, Take It (15th Annual Health Sciences Lively Lunch): Developments 2014-2015
- Description:
- Handout prepared for and presented in synopsis during a brief (traditional) annual update of interesting and noteworthy trends in the health publishing and health information sectors that occurred or were noticed since the 2014 Health Sciences Lively Lunch at the Charleston Conference: Issues in Book and Serial Acquisition. (15th Lively Lunch took place on Friday, November 6, 2015 in Charleston, SC).
- Original Bibliographic Citation:
- When You Come to a Fork in the Road: Take It (15th Annual Health Sciences Lively Lunch) [presentation at 2015 Charleston Conference, November 6, 2015, Charleston, SC]
- Abstract:
- In this year's sponsored, but no holds barred lunch, participants contemplated examples of proactive approaches answering the question posed by the 2015 conference theme, “Where Do We Go From Here?”. After greetings from the lunch host, Rittenhouse, and the traditional brief “year in review” recap by Ramune Kubilius, three panelists shared insights and open the floor for lively discussion with session participants. Researchers increasingly must meet various data management requirements and mandates, while educators are challenged by changing trends in providing curricular content. Where does that leave libraries? In the best case scenarios, they utilize approaches espoused in Yogi Berra’s advice—they follow paths (opportunities) that present themselves, and become partners. Cunera Buys described work she and Pamela Shaw (Biosciences & Bioinformatics Librarian, Northwestern University’s Galter Health Sciences Library) did in the data management planning arena, as part of a university working group. She touched on differing disciplinary needs and how data management affects scholarly publishing and communication activities. Are alternate open textbooks a solution for educators seeking health sciences curricular reading materials? Elizabeth Lorbeer discussed the current environment, experiments, and roles (“reinvented” expertise) librarians can share in order to help faculty and students. Finally, before moving to longer lively discussion, moderator Jean Gudenas rounded out the panel by sharing examples of recent developments and experiments, how libraries strive to demonstrate value in the collections and document delivery arena.
- Keyword:
- health sciences, scholarly publishing, libraries
- Subject: MESH:
- Libraries, Medical, Publishing
- Subject: LCSH:
- Publishing, Medical libraries
- Creator:
- Kubilius, Ramune Karolina
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Charleston, South Carolina, United States
- Language:
- English
- Date Created:
- 2015
- Rights:
- http://creativecommons.org/licenses/by-sa/3.0/us/
- Resource Type:
- Presentation
6441. VIVO Around the World
- Title:
- VIVO Around the World
- Description:
- Creating a diagram showing investigator collaborations through publications
- Keyword:
- VIVO, Visualization, Collaboration
- Subject: MESH:
- Authorship, Cooperative Behavior, Data Display
- Subject: LCSH:
- Information visualization, Authorship--Collaboration
- Creator:
- Friedman, Paul
- Contributor:
- Kibbe, Warren A, Ilik, Violeta, Holmes, Kristi, Starren, Justin B
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Language:
- English
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Poster
6442. Bienvenido a VIVO
- Title:
- Bienvenido a VIVO
- Description:
- Moving from a custom application to one that uses VIVO-compatible Linked Open Data.
- Keyword:
- VIVO, Visualization, LatticeGRID, RDF, Open Data
- Subject: MESH:
- Data Display, Data Mining, Information Storage and Retrieval
- Subject: LCSH:
- Linked data, Ontologies (Information retrieval), Information visualization
- Creator:
- Friedman, Paul, Kibbe, Warren A, Ilik, Violeta, Holmes, Kristi, Starren, Justin B
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Language:
- English
- Rights:
- http://creativecommons.org/publicdomain/zero/1.0/
- Resource Type:
- Poster
- Title:
- Disciplinary Perceptions of Data and Data Management Practices
- Description:
- Poster presented at the Medical Library Association 2015 annual conference. Poster was created from data collected in a survey of Northwestern University researchers from all disciplines across all schools in early 2015.
- Abstract:
- Data storage requirements and management services are topics of interest in academic libraries and computing centers. Many academic institutions’ libraries have undertaken surveys of faculty in an effort to determine attitudes and needs for data storage and management. Our institution’s E-Science Working Group conducted a similar survey, extending it beyond faculty to also include graduate students, post-doctorates and research staff. A survey of data management practices across the entire university including all disciplines was designed in late 2013 using Qualtrics survey software. The survey was distributed via email link to approximately 12,900 email addresses at the university in January 2014 and was closed in February 2014. The group analyzed the results in spring 2014 utilizing Atlas.ti and Qualtrics analytics. The survey received 831 responses with 788 responders completing the survey. Results reveal that users at Northwestern University are uncertain of how much data storage they will need in the future, have a strong desire for instruction and services surrounding data management practices and that there is a trend toward a data sharing culture at the institution. Based on analysis of the data management survey, it appears that there is no consensus on exactly how to store, share or manage data. Even more striking is the observation that the understanding of what constitutes “data” can be widely interpreted, depending on academic discipline.
- Keyword:
- data management
- Subject: MESH:
- Data Curation, Information Dissemination
- Creator:
- Shaw, Pamela L, Buys, Cunera M
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Austin, Texas, United States
- Language:
- English
- Date Created:
- 2015-04-27
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Poster
- Title:
- DigitalHub - a living record of scholarly output
- Description:
- Presentation given at the Fedora Users Group meeting in Chicago, IL on October 22, 2015.
- Keyword:
- Repository, RDF, OWL
- Subject: MESH:
- Information Storage and Retrieval
- Subject: LCSH:
- Digital libraries--United States, RDF (Document markup language), Ontologies (Information retrieval)
- Creator:
- Ilik, Violeta
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2015-10-22
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Presentation
6446. National Library of Medicine 2nd Year Associate Fellowship, Washington University in St. Louis
- Title:
- National Library of Medicine 2nd Year Associate Fellowship, Washington University in St. Louis
- Description:
- Presentation to the librarians of the Arizona Health Sciences Library of the University of Arizona on March 24, 2014 on reflections from the 2nd year of the National Library of Medicine's Associate Fellowship program.
- Keyword:
- National Library of Medicine, NLM Fellows, NLM Fellowship, Arizona Health Sciences Library
- Subject: MESH:
- Fellowships and Scholarships
- Subject: Name:
- National Library of Medicine (U.S.), University of Arizona. Health Sciences Library
- Creator:
- Gutzman, Karen E
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Tucson, Arizona, United States
- Language:
- English
- Date Created:
- 2014-03-24
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Presentation
- Title:
- Core Informatics Competencies for Clinical and Translational Science Trainees
- Abstract:
- These competencies are focused at the master's degree level for clinician scientists enrolled in translational research training programs. They are intended to enable clinician scientists to utilize existing informatics tools and to collaborate effectively with informatics specialists in order to make use of best practices for the generation, storage, management, retrieval, use, sharing, presentation, protection and analysis of biomedical and health information in clinical and translational research.
- Keyword:
- Clinical and Translational Research, Education, Competencies, CTSA
- Subject: MESH:
- Translational Research, Biomedical--education, Medical Informatics--education, Competency-Based Education, Clinical Competence
- Creator:
- Starren, Justin B, Valente, Annette, Meagher, Emma, Tachinardi, Umberto
- Contributor:
- American Medical Informatics Association. Clinical Research Informatics Work Group, Clinical and Translational Science Awards Consortium. Biomedical Informatics Training Work Group
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2014-11-24
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Guideline
6448. The New NIH Biosketch
- Title:
- The New NIH Biosketch
- Description:
- How to showcase your research impact in the new NIH Biosketch format.
- Abstract:
- Recent changes in the NIH Biosketch format have left many scientists facing a challenge: how does one best document the influence of their work when applying for funding? In this webinar, experts from Northwestern University and Altmetric will share the most important strategies for crafting a “must-fund” NIH Biosketch.
- Keyword:
- altmetrics, alternative metrics, research impact, NIH biosketch
- Subject: MESH:
- Autobiographies as Topic, Statistics as Topic, Biomedical Research
- Subject: Name:
- National Institutes of Health (U.S.)
- Creator:
- Gutzman, Karen E, Shaw, Pamela L
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2015-10-14
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Presentation
- Title:
- Photograph of a Sinhalese ola written in Pali ca. 1760 CE (closed)
- Description:
- Photograph of an Ola (palm-leaf manuscript) written in Pali around 1760 AD. , The binding cord, ivory carved medallion, and lacquered wood covers are modern, made in Ceylon by native artists after ancient models., This ola and another ola were featured on the DigitalHub home page at initial launch in October 2015., [Donated by Dr. Casey Wood, 1934. Photo by James B. Brucker, 2005.] PHOTO Credit line should read: "Courtesy of the Galter Health Sciences Library Special Collections, Feinberg School of Medicine, Northwestern University, Chicago, Ill."
- Abstract:
- About 250 years old, this ola contains information on medical care for conditions for eyes and nose. It prescribes recipes for snuffs for catarrhs, ointments and pastes for eye diseases, and decoctions and powders for nasal and eye diseases.
- Keyword:
- Sinhalese Ola, Ophthalmology, Rare books, Special collections
- Subject: MESH:
- Ophthalmology, Otolaryngology, Medicine, Traditional
- Subject: Geographic Name:
- Sri Lanka
- Creator:
- Brucker, James B
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Page Number:
- 1
- Language:
- Pali
- Date Created:
- 1760
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Photographs
- Title:
- Photograph of the Dr. Casey Wood display
- Description:
- This display includes Sinhalese olas donated to the Galter Health Sciences Library (formerly the Archibald Church Medical Library) by Dr. Wood and currently housed in the Library's Special Collections. It also includes includes articles, books and journals written by Dr. Woods. , [Photo by James Brucker is from a 2005 Galter Library display prepared by Special Collections Librarian, Ron Sims, showcasing the olas and various other items donated by Dr. Wood.] PHOTO Credit line should read: "Courtesy of the Galter Health Sciences Library Special Collections, Feinberg School of Medicine, Northwestern University, Chicago, Ill."
- Abstract:
- The collection of olas deals with many medical topics including the treatment of eye and skin diseases, and are written in Sanskrit, Pali, and Sinhalese. The texts, incised on palm leaves, were written by both practitioners and students of medicine between 1400 and 1770 CE. Though their original bindings did not survive, they are secured by modern painted wood covers modeled on the old design and crafted by Sinhalese artisans.
- Keyword:
- Sinhalese Ola, Special collections, Rare books, Ophthalmology
- Subject: MESH:
- Ophthalmology, Medicine, Traditional
- Subject: Name:
- Wood, Casey A. (Casey Albert), 1856-1942
- Creator:
- Brucker, James B
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Page Number:
- 2
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Photographs
- Title:
- Photograph of a Sinhalese ola written in Pali ca. 1760 CE (open)
- Description:
- Photograph of an Ola (palm-leaf manuscript) written in Pali around 1760 AD. , The binding cord, ivory carved medallion, and lacquered wood covers are modern, made in Ceylon by native artists after ancient models., This ola and another ola were featured on the DigitalHub home page at initial launch in October 2015., [Donated by Dr. Casey Wood, 1934. Photo by James B. Brucker, 2005.] PHOTO Credit line should read: "Courtesy of the Galter Health Sciences Library Special Collections, Feinberg School of Medicine, Northwestern University, Chicago, Ill."
- Abstract:
- About 250 years old, this ola contains information on medical care for conditions for eyes and nose. It prescribes recipes for snuffs for catarrhs, ointments and pastes for eye diseases, and decoctions and powders for nasal and eye diseases.
- Keyword:
- Sinhalese Ola, Ophthalmology, Rare books, Special Collections
- Subject: MESH:
- Ophthalmology, Otolaryngology, Medicine, Traditional
- Subject: Geographic Name:
- Sri Lanka
- Creator:
- Brucker, James B
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Page Number:
- 3
- Language:
- Pali
- Date Created:
- 1760
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Photographs
- Title:
- Adopting and implementing an open access policy: the library's role
- Description:
- Recording of presentation by Brian Kern at the North American Serials Interest Group (NASIG) 2013 conference, June 6-9, 2013 in Buffalo, New York.
- Original Bibliographic Citation:
- Kern, Brian [presenter] and Wishnetsky, Susan [recorder]. "Adopting and implementing an open access policy: the library's role" [manuscript version]. Presented at the North American Serials Interest Group (NASIG) 2013 Conference, June 6-9, 2013, Buffalo, New York. Published in *Serials Librarian*, v.66, no.1/4 (2014), pp. 196-203. DOI of published version: 10.1080/0361526X.2014.880035
- Abstract:
- With the support of the library, the faculty, and the administration, Allegheny College recently adopted the strongest type of open access policy, a mandate for all faculty scholarship to be placed in the college’s institutional repository. The library’s Head of Technical Services tells how the policy came to be approved and how it is being implemented by the library.
- Keyword:
- Open Access Institutional Repository
- Subject: MESH:
- Information Storage and Retrieval, Information Systems, Libraries
- Subject: LCSH:
- Institutional repositories
- Creator:
- Wishnetsky, Susan J, Kern, Brian
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Buffalo, New York, United States
- Language:
- English
- Date Created:
- 2013-07-22
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Presentation
- Title:
- Integrating LCSH and MeSH in Information Systems
- Description:
- Manuscript for a book chapter in Subject Retrieval in a Networked Environment (see full bibliographic citation), adapted from a presentation given at an IFLA Satellite Meeting held in Dublin, OH, 14-16 August 2001.
- Original Bibliographic Citation:
- Tony Olson. “Integrating LCSH and MeSH in Information Systems,” in Subject Retrieval in a Networked World : proceedings of the IFLA Satellite Meeting held in Dublin, Ohio, 14-16 August 2001 (Munich, Germany : K.G. Saur, 2003)
- Abstract:
- The Library of Congress Subject Headings system, and the National Library of Medicine's Medical Subject Headings thesaurus have been mapped. The mapping data has been entered into 7XX fields of USMARC authority records. The data continues to be updated as subject headings are added, deleted, or changed in both information languages. It is planned to distribute the mapping data in both MARC and non-MARC formats to libraries, vendors, bibliographic utilities and other developers of information systems.
- Keyword:
- Subject Semantic Interoperability, Subject Headings
- Subject: MESH:
- Subject Headings, Medical Subject Headings, Information Storage and Retrieval
- Subject: LCSH:
- Subject headings, Subject headings, Library of Congress, Information Retrieval
- Creator:
- Olson, Tony (Librarian), 1938-
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Dublin, Ohio, United States
- Language:
- English
- Date Created:
- 2001-09-19
- Rights:
- http://creativecommons.org/licenses/by-nc-nd/3.0/us/
- Resource Type:
- Manuscript
- Title:
- Integration of Information Languages and Interoperability
- Description:
- Presented at the Program: "Real World Steps to Interoperability in Libraries", sponsored by the LITA/ALCTS Authority Control in the Online Environment Interest Group, American Library Association Annual Conference, June 16, 2002, Atlanta, Georgia.
- Keyword:
- Subject Semantic Interoperability, Subject Headings, Information Retrieval
- Subject: MESH:
- Information Storage and Retrieval, Subject Headings, Medical Subject Headings
- Subject: LCSH:
- Subject Headings, Subject headings, Library of Congress, Information retrieval
- Creator:
- Olson, Tony (Librarian), 1938-
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 1992-06-16
- Rights:
- http://creativecommons.org/licenses/by-nc-nd/3.0/us/
- Resource Type:
- Presentation
- Title:
- Dos and Don'ts of extending the VIVO ontology
- Description:
- Presentation given at the VIVO iFest 2015, Portland Oregon.
- Keyword:
- RDF, Ontology, OWL, VIVO
- Subject: MESH:
- Information Storage and Retrieval
- Subject: LCSH:
- Ontologies (Information retrieval), RDF (Document markup language)
- Creator:
- Ilik, Violeta
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Portland, Oregon, United States
- Language:
- English
- Date Created:
- 2015-03-16
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Presentation
- Title:
- Promoting Special Collections with a Medical School’s Sesquicentennial Celebration
- Original Bibliographic Citation:
- Shedlock, J. and Sims, R. Promoting Special Collections with a Medical School’s Sesquicentennial Celebration. Poster presented at the Medical Library Association's annual meeting, Honolulu, HI, May 2009.
- Abstract:
- Northwestern University’s Feinberg School of Medicine celebrates its sesquicentennial in 2009. The Galter Health Sciences Library’s Special Collections is often used to promote the library in the life of its medical school, and this year it fulfills a crucial, supporting role in the sesquicentennial celebrations. Because much of the school’s history is located in the Special Collections’ resources, it is the library’s responsibility to share this history and use it as a means of promoting the school’s future excellence in education, research and patient care based on a record of past success. When the sesquicentennial celebration ends, the library will have played a significant role in promoting the medical school, advancing the role of the library and demonstrating the value of history and preservation in the life of the school.
- Keyword:
- medical libraries, history of medicine
- Subject: MESH:
- History of Medicine, Schools, Medical, Libraries, Medical
- Subject: Name:
- Feinberg School of Medicine
- Creator:
- Shedlock, James, Sims, Ronald H
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Honolulu, Hawaii, United States
- Language:
- English
- Date Created:
- 2009
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Poster
- Title:
- History of medicine: projects, presentations, and exhibits
- Keyword:
- medical school, history of medicine, Northwestern University, Feinberg School of Medicine, Northwestern University Medical School, Special Collections, Galter Health Sciences Library
- Subject: MESH:
- History of Medicine, History of Dentistry
- Creator:
- Kubilius, Ramune Karolina
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Exhibitions, Poster, Presentation
- Title:
- Starting from scratch – building the perfect digital repository
- Original Bibliographic Citation:
- Starting from scratch – building the perfect digital repository - Piotr Hebal, Violeta Ilik, and Kristi Holmes - Open Repositories 2015, Indianapolis, IN, June 9, 2015
- Abstract:
- By establishing a digital repository for the Feinberg School of Medicine (FSM) (Northwestern University, Chicago campus), we anticipate gaining the ability to create, share, and preserve attractive, functional, and citable digital collections and exhibits. Galter Health Sciences Library did not have a repository as of November 2014. In just a few months we formed a small team that was charged at looking to select the most suitable open source platform for our digital repository software. We followed the National Library of Medicine master evaluation criteria by looking at various factors that included: functionality, scalability, extensibility, interoperability, ease of deployment, system security, system, physical environment, platform support, demonstrated successful deployments, system support, strength of development community, stability of development organization, and strength of technology roadmap for the future. These factors are important for our case considering the desire to connect the digital repository with platforms that produce VIVO compatible structured linked data. VIVO is a linked data platform that serves as a researchers’ hub and which provides the names of researchers from academic institutions along with their research output, affiliation, research overview, service, background, researcher’s identities, teaching, and much more.
- Keyword:
- Repository, Ontology, Controlled vocabularies
- Subject: LCSH:
- Digital libraries, Digital libraries--Collection development, Ontologies (Information retrieval), RDF (Document markup language)
- Creator:
- Ilik, Violeta, Hebal, Piotr, Holmes, Kristi
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Indianapolis (Ind.)
- Language:
- English
- Date Created:
- 2015-06-09
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Poster
- Title:
- One (Online) Site: A New Paradigm for MLA Concurrent Session Planning?
- Original Bibliographic Citation:
- Kubilius RK and Rethlefsen ML. "One (Online) Site: A New Paradigm for MLA Concurrent Session Planning?". Poster Presentation, Medical Library Association annual meeting, Boston, MA, May 2013 and Midwest Chapter / MLA annual meeting, East Peoria, IL, October 2013.
- Abstract:
- Objectives: To assess the effectiveness and usability of an online section/special interest group (SIG) program planning process for the One Health meeting and to investigate whether the time has come for the process to move online for future meetings. Methods: Traditionally, MLA has required that section and SIG planners attend two on-site meetings that take place the year prior to the meeting being planned. An experiment grew out of necessity when planning for the 2013 international federated meeting that resulted in a meeting planning timeline that did not follow the usual pattern. An alternative method was devised, implemented, and tested. All 2013 program planners will be invited to participate in a survey to gauge their satisfaction with the online session theme planning process. A follow-up interview will be conducted with those planners who had earlier experience with the previous planning process. Results: Thirty-four planners (from all 23 sections and 7 SIGs) responded to the survey. One respondent had not used the online planning site at all, due to inaccessibility of Google Sites at work. Of the remaining 33 respondents, 17 were first-time program planners. Responses about the site were generally positive (4 responses from experienced users were negative about usability, and 3 indicated it was ineffective). Nonusers of the online tutorials perceived the site's usability negatively or very positively, though perceived site effectiveness did not differ by tutorial usage. The overall online planning process was perceived slightly less positively, and 3 experienced planners felt the 2013 process was worse than their previous experience (same n=7, better n=5). Most planners favored adding an in-person component, though 3 felt it would not have benefited the process, and 11, primarily first-timers, were unsure. Communication challenges were mentioned in qualitative survey comments and focus group discussions, though it was acknowledged that the online process allowed more people to participate in a more efficient, trackable manner. Strong leadership, perceived as evident for 2013, could ensure future success with online planning. Conclusions: For the online planning process to succeed in the future, an in-person component should be retained as a supplement.
- Keyword:
- medical libraries
- Subject: MESH:
- Libraries, Medical, Library Associations
- Subject: Name:
- Medical Library Association
- Creator:
- Kubilius, Ramune Karolina, Rethlefsen, Melissa
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Boston, Massachusetts, United States, East Peoria, Illinois, United States
- Language:
- English
- Date Created:
- 2013
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Poster
- Title:
- Promoting and Teaching the History of Medicine in an Undergraduate Curriculum
- Description:
- Paper Presentation, Medical Library Association annual meeting, Honolulu, HI, May 2009.
- Original Bibliographic Citation:
- Shedlock J; Sims R; Kubilius R. "Promoting and Teaching the History of Medicine in an Undergraduate Curriculum". Paper Presentation, Medical Library Association annual meeting, Honolulu, HI, May 2009.
- Abstract:
- Objective: This paper describes the development of a history seminar for a medical school’s course on "Physician, Patient and Society." The genesis of the seminar responds to the librarians’ desire to promote the use of the library’s special collections, especially rare books, among students in the undergraduate MD curriculum. The medical school, its library, and the MD curriculum are described. Methods: The MD course is "Patient, Physician and Society" and is included in both year 1 and year 2 curricula. The history seminar is an option among 20+ humanities seminars offered to students; students are required to choose one seminar. The history seminar is 5 sessions long and is limited to 6 students; the seminar is offered in successive weeks to year 1 and then year 2 students each January and February. Students choose a disease or health condition and trace its history back in time, using the rare books as supporting evidence. A PowerPoint presentation is required at the last session to reinforce the use of technology as a teaching tool and to promote teaching skills among students.
- Keyword:
- Special Collections, medical education, Galter Health Sciences Library, Northwestern University
- Subject: MESH:
- History of Medicine, Education, Medical, Librarians, Libraries, Medical
- Creator:
- Kubilius, Ramune Karolina, Shedlock, James, Sims, Ronald H
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2009
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Presentation
- Title:
- The Impact of Open Access on Scientific Discovery & Publishing
- Description:
- A presentation on the history of publication and data sharing in science, and how this has affected scientific progress. Presented during Open Access Week, 2009. Data on slides may be outdated, but links are updated.
- Keyword:
- Open Access
- Subject: MESH:
- Science, Information Dissemination
- Subject: LCSH:
- Open access publishing
- Creator:
- Shaw, Pamela L
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2009-10-21
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Presentation
6462. Trends in Health Sciences and Biomedical Sciences Information and Services Provision: Introduction
- Title:
- Trends in Health Sciences and Biomedical Sciences Information and Services Provision: Introduction
- Description:
- Originally published in: Kubilius, Ramune K. Trends in Health Sciences and Biomedical Sciences Information and Services Provision. [Introduction]. Against the Grain. 2014; 26(2):1,8,10. https://docs.lib.purdue.edu/atg/vol26/iss2/. PDF of article posted with publisher's permission.
- Original Bibliographic Citation:
- Kubilius, Ramune K. Trends in Health Sciences and Biomedical Sciences Information and Services Provision. [Introduction]. Against the Grain. 2014; 26(2):1,8,10.
- Abstract:
- This special ATG issue includes seven contributions by experienced authors who share insights and their own experiences. They address current trends and opportunities addressed or undertaken by those who work with persons involved in the triad of patient care, education, and research, and beyond. [excerpt of Introduction by editor of this special issue of Against the Grain]
- Keyword:
- medical libraries
- Subject: MESH:
- Libraries, Medical, Publishing--trends, Information Services--trends
- Subject: LCSH:
- Scholarly publishing
- Creator:
- Kubilius, Ramune K.
- Publisher:
- Against the Grain, DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Introductory Journal Article
- Title:
- Learning About the World of Special Collections: stewardship, inventories, treasure hunts, genealogy...
- Description:
- Adaptation of poster presented at the Midwest Chapter / Medical Library Association annual conference in Louisville, KY, October 2015.
- Original Bibliographic Citation:
- Learning About the World of Special Collections: stewardship, inventories, treasure hunts, genealogy.../Ramune K. Kubilius [poster]. Presented at the Midwest Chapter / Medical Library Association annual conference in Louisville, KY, October 2015.
- Abstract:
- Even while many academic health sciences libraries are increasingly becoming immersed in clinical and translational science, systematic reviews and other institutional endeavors, historical and genealogical questions as well as projects continue to thrive. The scope of the work can be varied and challenging, involving many interested players and stakeholders, both internal and external. How might the formula of librarians, evidence, or proof apply in the case of historical queries and work when staffing devoted to activities is not full-time, and also interim or transitional? The song title "Time Waits For No One" (Rolling Stones, 1974) aptly describes the juggling act of addressing inquiries, moving things along, trying to be a good steward, documenting work done, and participating in planning for future traditional format and digital scenarios. Can any health sciences librarian step in to do this work if needed? Where does one begin? How does one identify a particular library’s treasures? How does one provide evidence of the value of this area of the library’s work? In this poster, some logs and visualizations will represent a case study of one institution’s Special Collections and related historical work of the past year, some treasures discovered, and some lessons learned that might resonate with others. One wants to change the words of the song, “The Middle of the Road is Trying to Find Me” (Pretenders, 1984) to be the more pro-active acclamation: “I am trying to find the middle of the road and will go down it with purpose”.
- Keyword:
- Special Collections, libraries, Medical Library Association
- Subject: MESH:
- Librarians, History of Medicine, Schools, Medical, Schools, Dental
- Creator:
- Kubilius, Ramune Karolina
- Contributor:
- Kubilius, Ramune Karolina
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Poster
- Title:
- From talking dogs to personalized medicine: The weird and wonderful history of inheritance and pharmacogenomics from pups to people
- Description:
- A presentation made at the Medical Library Association annual conference in May 2015. The topic was the importance of the dog as a model in inheritance and disease.
- Keyword:
- dogs, pharmacogenomics, canine evolution
- Subject: MESH:
- Dogs, Pharmacogenetics, Inheritance Patterns, Models, Animal
- Subject: LCSH:
- Dogs, Pharmacogenomics, Pharmacogenetics--Animal models
- Creator:
- Shaw, Pamela L
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Austin, Texas, United States
- Language:
- English
- Date Created:
- 2015-05-10
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Presentation
- Title:
- Study of Epstein Barr virus glycoprotein 42 and virus contribution to Burkitt Lymphoma pathogenesis utilizing bioinformatics tools
- Keyword:
- bioinformatics, virology, pathway analysis, Epstein-Barr virus
- Subject: MESH:
- Virology, Computational Biology, Herpesvirus 4, Human, Burkitt Lymphoma--etiology
- Subject: LCSH:
- Virology, Bioinformatics, Epstein-Barr virus, Epstein-Barr virus diseases, Burkitt's lymphoma
- Creator:
- Shaw, Pamela L
- Publisher:
- Northwestern University, DigitalHub. Galter Health Sciences Library
- Language:
- English
- Date Created:
- 2010-05-19
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Masters Thesis
- Title:
- What do MARC, RDF, and OWL have in common?
- Description:
- Presentation given at the Program for Cooperative Cataloging (PCC) Participants Meeting during American Library Association Annual Meeting, San Francisco, CA, June 28, 2015
- Original Bibliographic Citation:
- Ilik, Violeta. What do MARC, RDF, and OWL have in common? Program for Cooperative Cataloging (PCC) Participants Meeting. American Library Association Annual Meeting, San Francisco, CA, June 28, 2015
- Abstract:
- It is understood that in the current library ecosystem, catalogers must be willing to adapt to new semantic web environment while keeping in mind the crucial library mission providing efficient access to information. How could catalogers transform their jobs in order to enable library users to retrieve information more effectively in the age of semantic web? Researchers have argued that catalogers have the fundamental skills to successfully work with and repurpose the metadata originally created for use in traditional library systems by utilizing various programing languages. In the new environment their jobs will require new tools and new systems but the basic skills of organization of information, knowledge of commonly used access points, and an ever growing knowledge of information technology systems will still be the same. This presentation will stress the role of catalogers in bringing the data silos down, merging, augmenting, and creating interoperable data that can be used not just in library specific systems, but in various other systems. Catalogers indispensable knowledge of controlled vocabularies, authority aggregators, metadata creation, metadata reuse, taxonomies, and data stores makes it all possible. We will demonstrate how catalogers knowledge can be leveraged to design an institutional repository and/or a researchers profiling system, create semantic web compliant data, create ontologies, utilize unique identifiers, and (re)use data from legacy systems.
- Keyword:
- Ontology, Semantic Web, RDF
- Subject: MESH:
- Vocabulary, Controlled, Semantic Web
- Subject: LCSH:
- Ontologies (Information retrieval), RDF (Document markup language), Semantic Web
- Creator:
- Ilik, Violeta
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- San Francisco, California, United States
- Language:
- English
- Date Created:
- 2015-06-28
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Presentation
- Title:
- Special Collections: photos from the vault
- Description:
- Photographs of historical and/or institutional interest from Northwestern University Galter Health Sciences Library's Special Collections.
- Keyword:
- historical photographs
- Subject: MESH:
- Schools, Medical--history
- Subject: Geographic Name:
- Chicago (Ill.)
- Subject: Name:
- Feinberg School of Medicine, Northwestern University (Evanston, Ill.). Medical School
- Creator:
- Kubilius, Ramune Karolina
- Contributor:
- Galter Health Sciences Library. Special Collections.
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Photographs
- Title:
- Using VIVO-ISF Ontology in Open Repositories
- Original Bibliographic Citation:
- Using VIVO-ISF Ontology in Open Repositories. Violeta Ilik, Piotr Hebal, and Kristi Holmes. VIVO 2015 Conference, Cambridge, MA, August 13, 2015. https://dx.doi.org/10.6084/m9.figshare.2002149
- Keyword:
- Ontology, Open Repositories, RDF, Semantic Web
- Subject: MESH:
- Vocabulary, Controlled, Libraries, Digital
- Subject: LCSH:
- Semantic Web, Ontologies (Information retrieval), RDF (Document markup language), Institutional repositories
- Creator:
- Ilik, Violeta, Hebal, Piotr, Holmes, Kristi
- Publisher:
- DigitalHub. Galter Health Sciences Library
- Location:
- Cambridge, Massachusetts, United States
- Language:
- English
- Date Created:
- 2015-08-13
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Presentation