A Framework for Maintaining a Fully Operational Autopsy Service at a Large Academic Teaching Institution During a Global Pandemic
Original Bibliographic Citation:
Fu L, Zak T, Shanes E. A Framework for Maintaining a Fully Operational Autopsy Service at a Large Academic Teaching Institution During a Global Pandemic. Academic Pathology. 2021;8:8.
Abstract:
The COVID-19 pandemic created new challenges in health care, and pathology departments have led with innovations in testing and education. While the medical community and public showed great interest in gross and histologic findings in COVID-affected patients, paradoxically many autopsy services nationwide closed due to uncertainties surrounding the proximity to infected patient tissue, shortages in personal protective equipment, and pressures to discontinue perceived nonessential hospital operations. These disruptions furthermore negatively impacted pathology trainee education. The autopsy division at Northwestern Memorial Hospital, with the belief that a fully functioning autopsy service is especially crucial at this time, adopted a framework for continuing at full capacity for both clinical care and education. New operations were modeled on national protocols by the Centers for Disease Control and Prevention and the College of American Pathologists, and the service continually adjusted policies to reflect rapidly changing guidelines and feedback from trainees and staff. Between January and December 2020, we performed 182 adult autopsies including 45 COVID-19 autopsies. Twelve residents, 4 staff, and 5 attendings rotated through the service. In exit interviews, participants expressed: (1) improved comfort managing both COVID-related and general autopsies; (2) sense of personal safety on service (despite the increased risk of exposure); (3) belief that both COVID-related and general autopsies contributed to their personal education and to the medical community. There have been zero known autopsy-related COVID-19 infections to date. We hope that our innovative autopsy service restructuring can serve as a framework for other academic programs during the current and in future pandemics.
2019 Second Place, Northwestern Scientific Images Contest. We have all made bubbles by blowing air on a bubble wand dipped in a soap solution. Here, we make many small bubbles of uniform size by slowly injecting air into soapy water. The bubbles then arrange themselves in a uniform pattern-this is exactly how atoms arrange to form crystals. In fact, such bubble rafts were first used in 1940 to understand how crystals form. In this image, we see a single layer of bubbles arranged in a hexagonal pattern. The peculiar patterns are locations with two layers of bubbles sitting atop each other. Atomic crystals also show such irregular patterns, known as crystal defects.
Abstract:
This image originally appeared as part of Northwestern's Scientific Images Contest. The contest and subsequent exhibitions are organized by Science in Society, the University's research center for science education and public engagement. Further information and opportunities to participate are available on their website.
A clade of SARS-CoV-2 viruses associated with lower viral loads in patient upper airways
Original Bibliographic Citation:
Lorenzo-Redondo R, Nam HH, Roberts SC, Simons LM, Jennings LJ, Qi C, Achenbach CJ, Hauser AR, Ison MG, Hultquist JF, Ozer EA. A Clade of SARS-CoV-2 viruses associated with lower viral loads in patient upper airways. Ebiomedicine. 2020;62:10.
Abstract:
Background: The rapid spread of SARS-CoV-2, the causative agent of Coronavirus disease 2019 (COVID-19), has been accompanied by the emergence of distinct viral clades, though their clinical significance remains unclear. Here, we aimed to investigate the phylogenetic characteristics of SARS-CoV-2 infections in Chicago, Illinois, and assess their relationship to clinical parameters. Methods: We performed whole-genome sequencing of SARS-CoV-2 isolates collected from COVID-19 patients in Chicago in mid-March, 2020. Using these and other publicly available sequences, we performed phylogenetic, phylogeographic, and phylodynamic analyses. Patient data was assessed for correlations between demographic or clinical characteristics and virologic features. Findings: The 88 SARS-CoV-2 genome sequences in our study separated into three distinct phylogenetic clades. Clades 1 and 3 were most closely related to viral sequences from New York and Washington state, respectively, with relatively broad distributions across the US. Clade 2 was primarily found in the Chicago area with limited distribution elsewhere. At the time of diagnosis, patients infected with Clade 1 viruses had significantly higher average viral loads in their upper airways relative to patients infected with Clade 2 viruses, independent of disease severity. Interpretation: These results show that multiple variants of SARS-CoV-2 were circulating in the Chicago area in mid-March 2020 that differed in their relative viral loads in patient upper airways. These data suggest that differences in virus genotype can impact viral load and may influence viral spread.
Lorenzo Redondo, Ramon, Nam, Hannah H, Roberts, Scott C, Simons, Lacy Marie, Jennings, Lawrence J, Qi, Chao, Achenbach, Chad J, Hauser, Alan R, Ison, Michael G, Hultquist, Judd Franklin, Ozer, Egon Anderson
A 9-year-old boy with chronic progressive motor-sensory neuropathy beginning in early infancy and reversed by corticosteroid therapy is reported from the Institute of Neurological Diseases, Hirosaki University School of Medicine, Japan.
2019 Fifth Place, Northwestern Scientific Images Contest. Cancer treatments, while life preserving, can threaten fertility. Fertility preservation can be challenging in males with conditions of extremely low germ cell numbers or in those who have undergone testicular or epididymal biopsy where there may be limited numbers of immature germ cells. A significant clinical hurdle is the storage and recovery of small numbers of sperm. We engineered an oocyte-derived biomaterial the zona pellucida (ZP) to function as a sperm safe for storing sperm. The ZP is a glycoprotein matrix that surrounds the mammalian oocyte. Using a piezo drill, we made a small hole in the ZP and mechanically separated it from the oocyte cytoplasm and then further removed cellular material using a decellularization process. This images shows two deceullarized sperm safes imaged by scanning electron microscopy. The holes in which sperm are deposited within the sperm safes are clearly visible.
Abstract:
This image originally appeared as part of Northwestern Scientific Images Contest. The contest and subsequent exhibitions are organized by Science in Society, the University's research center for science education and public engagement. Further information and opportunities to participate are available on their website.
Researchers at Okayama University, Japan showed lactate dehydrogenase (LDH) inhibition suppresses neuronal excitation in vitro, reduces EEG discharges and seizures in rodent models, and may provide a novel mechanism for anticonvulsant medications in human patients.
This presentation was given as part of the Medical Library Association Webinar series on Wednesday, November 29, 2017 from 1:00 - 2:30 pm (Central Time).
Abstract:
8 Tips for Using Metrics in Research Evaluation offers librarians a quick, practical way to stay on top of the up-and-coming area of research evaluation and the role librarians can play in it. You will learn that you can easily transform your skills in expert searching and metadata into the valuable skills needed in the research evaluation process. Participants will be able to increase the impact of their work at their institutions, confidently answer questions related to research evaluation, and proactively seek new relationships with stakeholders who are interested in evaluation.
Keyword:
bibliometrics, research impact, alternative metrics, Galter Library
Subject: MESH:
Bibliometrics, Evaluation Studies as Topic
Creator:
Gutzman, Karen E, Smith, Patty Lauren, Holmes, Kristi
Publisher:
DigitalHub. Galter Health Sciences Library & Learning Center
The effect of the levorotatory form of 5-hydroxytryptophan (approx 1 gm/day/orally) on cerebellar symptoms in 26 patients with Friedreichs ataxia was evaluated in a double-blind drug-placebo study by the Ataxia Research Center, Hopital Neurologique, Lyon and 11 other research hospitals in France.
5,10-Methylenetetrahydrofolate Reductase Deficiency and Myoclonic Epilepsy
Abstract:
Investigators from the Children's Hospital of Philadelphia, PA, and McGill University, Montreal, Quebec, CA, report an adolescent learning-disabled girl who presented at age 14 years with an epilepsy syndrome initially diagnosed as juvenile myoclonic epilepsy.
See "1. PRO Planning Tools Overview" for a description of this collection of PRO planning tools, as well as a full list of authors at multiple institutions and complete funding acknowledgements.
2016 Second Place, This is a photograph of a human spine section, but these bones were 3D printed. This printed spine is smaller than in real life, but it is made almost entirely of the same mineral found in our bones (called hydroxyapatite). While we think of our bones as hard, here the same material is flexible and even elastic. This flexibility makes it easier and safer for surgeons to implant, and easier and faster for patients to heal. This new bone material -- called Hyperelastic Bone -- can help the body rapidly repair and regenerate damaged or missing bone.
Abstract:
This image originally appeared as part of Northwestern's Scientific Images Contest. The contest and subsequent exhibitions are organized by Science in Society, the university's research center for science education and public engagement. Further information and opportunities to participate are available on their website. Prints and canvas editions of these Northwestern research images can also be purchased online (with the small net profit going to science education and outreach programming in the Chicago area).
Keyword:
Human spine, Hydroxyapatite
Subject: MESH:
Spine, Printing, Three-Dimensional, Hydroxyapatites, Bone Substitutes
Creator:
Jakus, Adam Edward
Contributor:
Shah, Ramille Nirav
Publisher:
Science in Society, DigitalHub. Galter Health Sciences Library
See "1. PRO Planning Tools Overview" for a description of this collection of PRO planning tools, as well as a full list of authors at multiple institutions and complete funding acknowledgements.
The beneficial effects of oral L-serine (up to 500 mg/kg/day) and glycine (200 mg/kg/day) in 2 siblings, aged 7 and 5 years, with 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency are reported from University Childrens Hospital, Utrecht, The Netherlands.
This image originally appeared as part of Northwestern's Scientific Images Contest. The contest and subsequent exhibitions are organized by Science in Society, the university's research center for science education and public engagement. Further information and opportunities to participate are available on their website. Prints and canvas editions of these Northwestern research images can also be purchased online (with the small net profit going to science education and outreach programming in the Chicago area)., 2017 Second Place
Abstract:
This 3D-printed copper salt structure can be used in many ways. Here, it floats in a jar of water. The water dissolves the copper salt, resulting in a blue color, and transforming the structure into a very porous sponge-like material. When the salt has been completely dissolved, a polymer skeleton remains. This skeleton resembles the original 3D-printed shape but is incredibly light, like air.Creating materials like these is important because the "polymer skeletons sponge" can be used to implant all kinds of potent gel and liquid biomaterials during surgery. These fragile gels are currently being used to regenerate parts of tissues and organs.
2021-2022 Series 09 NUCATS Articulating your Mentoring Philosophy and Plan
Description:
Presentation discusses the different between a mentoring plan and mentoring philosophy, the "how's" and "why's" of mentoring, and creating a mentoring philosophy that is unique to you. This presentation was highly interactive leaving time for participants to reflect and write on their own throughout.
Keyword:
NUCATS, Mentoring, Mentoring Philosophy, Mentoring Plan
Subject: MESH:
Mentoring
Creator:
Goodman, Adam
Publisher:
DigitalHub. Galter Health Sciences Library & Learning Center
2021-2022 Series 08 NUCATS Dealing with Mentoring Challenges
Description:
Presentation discusses fundamental components of communicating effectively as a mentor, techniques to promote and facilitate workplace communication, and elements of conversation to deliver positive and negative feedback.
2021-2022 Series 07 NUCATS Goal Planning at Different Stages of One's Career
Description:
Develop awareness around how ones goals evolve over the course of their career. Discuss the distinction between goal setting and goal attainment. Identify strategies for developing goals (e.g., short-, intermediate, long-term) that fit within a long-term academic purpose.
Keyword:
NUCATS , Mentoring, Career goals
Subject: MESH:
Mentoring, Mentors
Creator:
Kalhan, Ravi, Khan, Sadiya Sana
Publisher:
DigitalHub. Galter Health Sciences Library & Learning Center
2021-2022 Series 06 NUCATS Dealing with Mentoring Challenges
Description:
Describe challenges in that commonly occur in mentoring relationships. Identify strategies for overcoming mentoring challenges. Identify a mentoring challenge that you will address.
2021-2022 Series 05 NUCATS Cultural Awareness to Enhance Mentoring Across Differences
Description:
Increase awareness of our own social identities and our perspectives about others social identities (i.e.,: race/ethnicity, gender, social class/socioeconomic status, sexual orientation, (dis)abilities, and religion). Recognize the impact of conscious and unconscious assumptions, preconceptions, biases, and prejudices on the mentor-mentee relationship and acquire skills to manage them. Identify concrete strategies for learning about others social identities and improving mentor-mentee relationships through culturally responsive mentoring.
Keyword:
NUCATS, Mentoring
Subject: MESH:
Mentoring, Mentors, Cultural Competency
Creator:
McGee, Rick, Kandula, Namratha R
Publisher:
DigitalHub. Galter Health Sciences Library & Learning Center
2021-2022 Series 04 NUCATS Fostering Independence/Transitioning your Mentee to Independence
Description:
Define Independence, its core elements, and how they change over time. Employ various strategies to build mentee confidence, establish trust, and foster independence. Identify benefits and challenges of fostering independence.
Keyword:
NUCATS Mentoring , Independence, Mentee
Subject: MESH:
Mentoring, Mentors
Creator:
Greenland, Philip, Cella, David
Publisher:
DigitalHub. Galter Health Sciences Library & Learning Center
2021-2022 Series 03 NUCATS Cultural Awareness to Enhance Mentoring Across Differences
Description:
- Increase awareness of our own social identities and our perspectives about others social identities (i.e.,: race/ethnicity, gender, social class/socioeconomic status, sexual orientation, (dis)abilities, and religion). - Recognize the impact of conscious and unconscious assumptions, preconceptions, biases, and prejudices on the mentor-mentee relationship and acquire skills to manage them.- Identify concrete strategies for learning about others social identities and improving mentor-mentee relationships through culturally responsive mentoring.
Keyword:
NUCATS, Mentoring
Subject: MESH:
Mentoring, Mentors, Cultural Competency, Social Identification
Creator:
McGee, Rick, Kandula, Namratha R
Publisher:
DigitalHub. Galter Health Sciences Library & Learning Center
Explores different ways to conceptualize the intersection of important domains in our lives (e.g. work-life integration vs. work-life balance vs. an integrated life). Identifies priorities and goals for integrating these important domains both at work and outside of work. Discusses the challenges and opportunities related to our current remote working environment, and how this can be leveraged to achieve a more integrated life.
Keyword:
NUCATS, Mentoring
Subject: MESH:
Mentoring, Mentors, Work-Life Balance
Creator:
Allen, Norrina Bai, O'Brien, Matthew James
Publisher:
DigitalHub. Galter Health Sciences Library & Learning Center
2021-2022 Series 01 NUCATS Establishing and Aligning Expectations
Description:
In this workshop presentation, viewers will: Examine existing expectations in your current mentoring relationships; question which expectations need to be revisited or discussed. Recognize and describe how one can apply a variety of tools to promote alignment in mentoring relationships. Choose 1-2 behavior changes you can enact in the next 3-6 months to improve alignment in your mentoring relationships.
Keyword:
Mentoring, NUCATS
Subject: MESH:
Mentoring, Mentors
Creator:
Cameron, Kenzie A, Carnethon, Mercedes R
Publisher:
DigitalHub. Galter Health Sciences Library & Learning Center
2020-2021 Series 08 NUCATS Articulating Your Mentoring Philosophy and Plan
Description:
Distinguish between a mentoring plan and a mentoring philosophy. Examine different mentoring experiences. List ~10 mentoring plan behaviors that most matter to you. Propose a mentoring philosophy that is unique to you.
Keyword:
Mentoring, NUCATS
Subject: MESH:
Mentoring, Mentors--education
Creator:
Goodman, Adam
Publisher:
DigitalHub. Galter Health Sciences Library & Learning Center
2020-2021 Series 07 NUCATS Evaluating Goals/Evaluating Your Mentee's Goals
Description:
Consider the role of including evaluation in goal setting. Discuss your approach to evaluating goals. Apply a standards-based framework to developing and evaluating goals.
Keyword:
Mentoring, NUCATS
Subject: MESH:
Mentoring, Mentors--education
Subject: LCSH:
Goal setting in personnel management
Creator:
Neubauer, Leah C
Publisher:
DigitalHub. Galter Health Sciences Library & Learning Center
2020-2021 Series 06 NUCATS Mentor Mapping and Developmental Networks
Description:
Compare and contrast the roles of mentors and/or developers in your academic career. Begin identifying their own developmental network (developers) who: Help get work done; Help in career advancement; Provide personal support; Serve as role models. Identify Career and Personal Goal Areas. Begin to identify relevant developers in each area. Appraise and Evaluate their initial Developmental Networks. Recognize the Need for Action Planning and Next Steps
Keyword:
Mentoring, NUCATS
Subject: MESH:
Mentoring, Mentors--education
Creator:
Sorond, Farzaneh A, Horowitz, Jeanne M, Cameron, Kenzie A
Publisher:
DigitalHub. Galter Health Sciences Library & Learning Center
2020-2021 Series 05 NUCATS Creating SMART Goals for your Feinberg Faculty Portal and your Career Development Plan
Description:
Describe the background and evidence-based benefits of goal setting. Discuss and critique the 5 specific components of SMART goals. Apply a goal setting framework to develop individualized goals to advance your career.
Keyword:
Mentoring, NUCATS
Subject: LCSH:
Goal setting in personnel management, Goal (Psychology)
Creator:
Weaver, Charlotta
Publisher:
DigitalHub. Galter Health Sciences Library & Learning Center
2020-2021 Series 04 NUCATS Cultural Awareness to Enhance Mentoring Across Differences
Description:
Increase understanding of equity and inclusion and their influence on mentor-mentee interactions. Recognize the impact of conscious and unconscious assumptions, preconceptions, biases, and prejudices on the mentor-mentee relationship and acquire skills to manage them. Identify concrete strategies for learning about and addressing issues of equity and inclusion.
Keyword:
Mentoring, NUCATS
Subject: MESH:
Mentoring, Mentors--education, Cultural Competency
Creator:
McGee, Rick, Kandula, Namratha R
Publisher:
DigitalHub. Galter Health Sciences Library & Learning Center
2020-2021 Series 03 NUCATS Maintaining Effective Communication/Difficult Conversations
Description:
Describe two fundamental components of communicating effectively as a mentor. Identify ineffective communication strategies and propose alternative effective techniques to promote communication. Discuss at least two elements of a conversation to deliver positive and negative feedback. List at least two effective communication techniques to facilitate a workplace conversation
Keyword:
Mentoring, NUCATS
Subject: MESH:
Mentoring, Mentors--education, Communication
Creator:
Carnethon, Mercedes R, Michelson, Kelly N
Publisher:
DigitalHub. Galter Health Sciences Library & Learning Center
2020-2021 Series 02 NUCATS Establishing and Aligning Expectations in Mentoring
Description:
Examine existing expectations in your current mentoring relationships. Question which expectations need to be revisited or discussed. Categorize your mentoring needs. Clarify and differentiate your expectations among multiple mentors (including secondary, team and/or peer mentors; coaches; and sponsors) to result in mutually beneficial relationships. Choose 1 2 behavior changes you can enact in the next 3 6 months to improve alignment in your mentoring relationships.
Keyword:
Mentoring, NUCATS
Subject: MESH:
Mentoring, Mentors--education
Creator:
Cameron, Kenzie A, McColley, Susanna
Publisher:
DigitalHub. Galter Health Sciences Library & Learning Center
2020-2021 Series 01 NUCATS Articulating Your Mentoring Needs
Description:
By the conclusion of this workshop presentation, attendees will: Identify 2-3 specific areas in which they are individually seeking mentoring; Describe at least 3 qualities of being an effective mentee; List 2-3 individual behavior changes that, if integrated into their mentoring relationships, could enhance mutual satisfaction with the relationship
Keyword:
Mentoring, NUCATS
Subject: MESH:
Mentoring, Mentors--education, Research
Creator:
Cameron, Kenzie A, Carnethon, Mercedes R
Publisher:
DigitalHub. Galter Health Sciences Library & Learning Center
The same scientific research that generates new understanding and innovation also brings unexpected and often breathtaking beauty. Submitted by Northwestern University researchers, these images represent advances across a wide range of disciplines, including astronomy, medicine, chemistry, engineering, and nanotechnology. Judged by an interdisciplinary panel of local artists, scientists and community leaders, the winning images have been displayed throughout the Chicagoland area, including Evanston Township High School and Evanston Public Library.
Scientific research often produces stunning images. The winners of the annual Northwestern Scientific Images Contest, showcase the captivating work being done across a range of Northwestern disciplines, from neurobiology to astrophysics. Free, public exhibitions and events share these images across Chicago each year, organized by Northwestern's research center for science education and community engagement, Science in Society.
Scientific research often produces stunning images. The winners of the annual Northwestern Scientific Images Contest, showcase the captivating work being done across a range of Northwestern disciplines, from neurobiology to astrophysics. Free, public exhibitions and events share these images across Chicago each year, organized by Northwestern's research center for science education and community engagement, Science in Society.
2015 Relaunch as Open Access Pediatric Neurology Briefs
Abstract:
Pediatric Neurology Briefs (PNB) has been published monthly since 1987 as a continuing education service designed to expedite and facilitate review of current medical literature concerning pediatric neurology. In 2015, PNB is relaunched as an open access, peer-reviewed, journal with an expanded editorial board. PNB has a new website and content management system capable of organizing peer-review and providing improved indexing, DOI assignment, and online full-text article view. Digitization of back issues, archiving, and inclusion in PubMed are future goals. The new online open access PNB aims to reach more physicians, researchers, and other healthcare providers with highlights of the latest advances in pediatric neurology and commentaries by specialists in the field.
Keyword:
Brain Diseases, Neurology, Pediatrics, Child Development, Nervous System Diseases
See "1. PRO Planning Tools Overview" for a description of this collection of PRO planning tools, as well as a full list of authors at multiple institutions and complete funding acknowledgements.