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- Title:
- Provider, Recipient and Caregiver Perspectives on Cardiovascular Disease and Related Risk Factors after Liver Transplantation: A Qualitative Study
- Abstract:
- Introduction: Liver transplant (LT) is the only life-saving therapy for end-stage liver disease stemming from a multitude of causes though cardiovascular disease (CVD) is the leading cause of early (<1 year) mortality, and the third leading cause of late (> 1 year) mortality after LT. (1-5) This study examined liver transplant recipient (LTR), caregiver, and provider perspectives on CVD after transplant. Barriers to proper care have not been identified for each group and we do not know how each group would describe these barriers. Methods: We conducted seven focus groups to better understand these barriers. The focus groups lasted 90 minutes and were split based on LTR, caregiver, and provider-specialty. The transcriptions for these focus groups were coded. Results: Four major themes found across all groups and are as follows: the lack of awareness of CVD risk after LT, the lack of confidence in ability to provide proper care to LTRs, barriers to care without transplant center review, and barriers caused by having to touch base with multiple providers on the complex care team. Conclusions: Potential solutions to eliminate these barriers include increased education on the risk factors of CVD amongst LTRs done by the transplant team, EMR alerts for providers, increased utilization of the transplant coordinator and the transplant pharmacist, multidisciplinary team meetings to discuss patients care plans, and an additional document detailing the roles of each member of the LTRs care team.
- Keyword:
- liver disease, cardiovascular disease, liver transplant
- Subject: MESH:
- Liver Diseases, Cardiovascular Diseases, Liver Transplantation, Communication Barriers
- Creator:
- Adamski, Lindsay
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2020-05-18
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Masters Thesis
- Title:
- Transitional Care for Trauma Surgery: A Scoping Review
- Keyword:
- Transitional Care, Trauma Surgery, Scoping Review
- Subject: MESH:
- Hospital to Home Transition, Continuity of Patient Care, Transitional Care, Patient Protection and Affordable Care Act, Wounds and Injuries
- Creator:
- Baskaran, Archit Bharathwaj, Silver, Casey Marie, Jang, Angie, Wafford, Q. Eileen
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Review
203. [Archived].docx
- Title:
- [Archived].docx
- Keyword:
- Transitional Care, Trauma Surgery, Scoping Review
- Creator:
- Baskaran, Archit Bharathwaj, Silver, Casey Marie, Jang, Angie, Wafford, Q. Eileen
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Research Paper
204. [Archived].docx
- Title:
- [Archived].docx
- Keyword:
- Transitional Care, Trauma Surgery, Scoping Review
- Creator:
- Baskaran, Archit Bharathwaj, Silver, Casey Marie, Jang, Angie, Wafford, Q. Eileen
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Research Paper
- Title:
- 2021-2022 Series 06 NUCATS Dealing with Mentoring Challenges
- Description:
- Describe challenges in that commonly occur in mentoring relationships. Identify strategies for overcoming mentoring challenges. Identify a mentoring challenge that you will address.
- Keyword:
- NUCATS, Mentoring, Mentoring challenges, Mentoring relationships
- Subject: MESH:
- Mentoring, Mentors
- Creator:
- Lagu, Tara, Evans, Charlesnika T
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-03-10
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Presentation
- Title:
- 2021-2022 Series 05 NUCATS Cultural Awareness to Enhance Mentoring Across Differences
- Description:
- Increase awareness of our own social identities and our perspectives about others social identities (i.e.,: race/ethnicity, gender, social class/socioeconomic status, sexual orientation, (dis)abilities, and religion). Recognize the impact of conscious and unconscious assumptions, preconceptions, biases, and prejudices on the mentor-mentee relationship and acquire skills to manage them. Identify concrete strategies for learning about others social identities and improving mentor-mentee relationships through culturally responsive mentoring.
- Keyword:
- NUCATS, Mentoring
- Subject: MESH:
- Mentoring, Mentors, Cultural Competency
- Creator:
- McGee, Rick, Kandula, Namratha R
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-02-23
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Presentation
- Title:
- 2021-2022 Series 04 NUCATS Fostering Independence/Transitioning your Mentee to Independence
- Description:
- Define Independence, its core elements, and how they change over time. Employ various strategies to build mentee confidence, establish trust, and foster independence. Identify benefits and challenges of fostering independence.
- Keyword:
- NUCATS Mentoring , Independence, Mentee
- Subject: MESH:
- Mentoring, Mentors
- Creator:
- Greenland, Philip, Cella, David
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-02-10
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Presentation
- Title:
- Analysis Considerations for Race, Ethnicity, and Gender Variables
- Abstract:
- The Department of Preventive Medicines (DPM) Working Group on Response to Structural Racism in Research, in collaboration with several members of the Division of Biostatistics, developed these considerations for best practices when summarizing and analyzing relevant demographic variables in Human Subjects Research. These considerations serve as guidelines and recommendations. They are not binding in any way. We recognize research studies each have unique needs, and there is no single set of best practices that would apply to all studies.
- Keyword:
- race, ethnicity, gender, inclusion, research, analysis, data capture
- Subject: MESH:
- Ethnic and Racial Minorities, Data Analysis, Gender Identity, Data Collection
- Creator:
- Ciolino, Jody Dyan, Kershaw, Kiarri N.
- Contributor:
- Northwestern Universitys Department of Preventive Medicines Working Group on Response to Structural Racism, Carnethon, Mercedes R, Granata IV, Frank Anthony, Gray, Elizabeth, Huffman, Mark D, Jones, Molly, Rodriguez, Monica, Neubauer, Leah C, Scholtens, Denise M
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-01-21
- Rights:
- http://creativecommons.org/licenses/by-sa/3.0/us/
- Resource Type:
- Support of Research
- Title:
- Considerations for Capturing of Race, Ethnicity, and Gender Data
- Abstract:
- The Department of Preventive Medicines (DPM) Working Group on Response to Structural Racism in Research surveyed multiple data dictionaries within DPM and beyond (e.g., Feinberg School of Medicine [FSM], United States Census, and the National Institutes of Health [NIH] reporting requirements). We assessed common practice and aggregated ideas from these sources to develop these considerations for best practices when capturing relevant demographic variables in Human Subjects Research. These considerations serve as guidelines and recommendations. They are not binding in any way. We recognize research studies each have unique needs, and there is no single set of best practices that would apply to all studies.
- Keyword:
- race, ethnicity, gender, inclusion, research, analysis, data capture
- Subject: MESH:
- Data Analysis, Ethnic and Racial Minorities, Gender Identity, Data Collection
- Creator:
- Ciolino, Jody Dyan, Kershaw, Kiarri N.
- Contributor:
- Northwestern Universitys Department of Preventive Medicines Working Group on Response to Structural Racism
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-01-21
- Rights:
- http://creativecommons.org/licenses/by-sa/3.0/us/
- Resource Type:
- Support of Research
- Title:
- Meta-Analysis: When You Can Do It, When You Can't, and What Info You Need
- Keyword:
- Statistically Speaking Slides
- Subject: MESH:
- Meta-Analysis as Topic, Systematic Reviews as Topic
- Creator:
- Collaboration Center, Biostatistics, Muhammad, Lutfiyya NaQiyba
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-01-12
- Rights:
- All rights reserved
- Resource Type:
- Lectures
- Title:
- Considerations for Choosing Covariates in Clinical Research
- Keyword:
- Statistically Speaking Slides
- Subject: MESH:
- Analysis of Variance, Research Design
- Creator:
- Collaboration Center, Biostatistics, Bonner, Lauren Balmert
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-12-09
- Rights:
- All rights reserved
- Resource Type:
- Lectures
- Title:
- Capturing Racial and Ethnic Data and Considerations for Analysis
- Keyword:
- Statistically Speaking Slides
- Subject: MESH:
- Data Analysis, Ethnic and Racial Minorities
- Creator:
- Collaboration Center, Biostatistics
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-02-03
- Rights:
- All rights reserved
- Resource Type:
- Lectures
- Title:
- Considerations when Leveraging Electronic Health Records for Causal Inference: A "Create-Your-Own-Data" Adventure
- Keyword:
- Statistically Speaking Slides
- Subject: MESH:
- Causality, Electronic Health Records, Data Analysis
- Creator:
- Collaboration Center, Biostatistics, Petito, Lucia Catherine
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-03-03
- Rights:
- All rights reserved
- Resource Type:
- Lectures
- Title:
- Maintenance of Diet and Activity Behaviors and Weight Loss After Intensive Lifestyle Intervention Scoping Review Protocol
- Abstract:
- Rationale: Although intensive lifestyle interventions tend to be successful at initiating weight loss, maintaining weight loss after withdrawal of intervention is more challenging. Also, it is unclear to what degree behavioral changes in dietary intake and physical activity that were made during weight loss initiation persist after treatment discontinuation and account for the observed variability in weight loss maintenance. A primary barrier to optimizing lifestyle interventions for long-term sustained improvement is the current lack of a coherent theoretical and methodological foundation for operationalizing maintenance. Indeed, there is variability in how researchers define, measure, and evaluate maintenance of both weight regulatory behaviors and weight loss following intervention. This variability in operationalizing maintenance could have significant implications for designing and optimizing interventions to achieve long-term maintenance. A synthesis of the available evidence on post-intervention behavioral weight loss maintenance is needed to lay a foundation that future researchers can use to appropriately design and implement interventions that produce meaningful, sustained healthful improvements in weight.
- Keyword:
- Protocol
- Subject: MESH:
- Body Weight Maintenance, Health Behavior, Diet, Food, and Nutrition, Exercise
- Creator:
- Daly, Elyse Renee, Battalio, Sam, Spring, Bonnie, Wafford, Q. Eileen, Pfammatter, Angela Fidler, Jovanovic, Christine Ernestine Schaak, Alshurafa, Nabil, Kalam, Faiza, Stump, Tammy Kay
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Rights:
- http://creativecommons.org/licenses/by-nc-nd/3.0/us/
- Resource Type:
- Review
- Title:
- Dried blood spots to measure the association between psychosocial factors and cardiovascular disease biomarkers: a scoping review
- Abstract:
- Scoping Review Question: What studies have used dried blood spots (DBS) to quantify cardiovascular disease (CVD) biomarkers in association with psychosocial factors? Psychosocial factors will include depression, anxiety, low socioeconomic status/poverty, incarceration, perceived discrimination, and other factors identified by this review.
- Keyword:
- dried blood spots, biomarkers, cardiovascular disease, psychosocial factors, population health
- Subject: MESH:
- Dried Blood Spot Testing, Cardiovascular Diseases, Psychosocial Functioning
- Creator:
- Jacobson, Tyler Andrew, Schwartz, William Alexander, Zhang, Runze, Wafford, Q. Eileen, Nunes, Denise A, Hirschhorn, Lisa Ruth, Khan, Sadiya Sana, Miller, Greg, McDade, Thomas, Funk, William E
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-01
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Review
- Title:
- Ethics of contributor roles ontologies and taxonomies - Scoping review protocol
- Abstract:
- Background: This scoping review follows up on the results of an exploratory review of the literature (Hosseini, 2021) about ethics of Contributor Role Ontologies and Taxonomies (CROTs). Given the significance of CROTs in scholarly publications, the current iteration will address methodological limitations of the exploratory review and will also capture sources published more recently.Objectives: This review aims to 1) synthesize the published literature about ethical aspects of CROTs and 2) categorize discussed aspects under specific ethical themes.Methods: Upon reviewing each source, information related to ethical aspects of CROTs will be synthesized to answer research questions. Sources that discuss ethical aspects of CROTs in a significant way in English will be included. Four indices (Scopus, Web of Science, PubMed, Google Scholar) will be searched without restriction on publication dates. Data will be charted in terms of mentioned research area(s), discussed CROTs, discussed ethical aspects (and in case of availability, other note-worthy information such as used normative approach, mentioned stakeholders, and provided solutions/recommendations will also be captured for further analysis).Results: Review results will be published open access in the peer-reviewed journal of Accountability in Research. Subsequently, the review results will inform the development of a survey to explore the views of the research community about the ethical evolution of CROTs.
- Keyword:
- Ethics, Contributor Role Ontologies and Taxonomies, Collaborative Research, Meta-Research
- Subject: MESH:
- Authorship, Ethics
- Creator:
- Hosseini, Mohammad, Gordijn, Bert, Wafford, Q. Eileen, Holmes, Kristi
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Rights:
- All rights reserved
- Resource Type:
- Review
- Title:
- 2021-2022 Series 03 NUCATS Cultural Awareness to Enhance Mentoring Across Differences
- Description:
- - Increase awareness of our own social identities and our perspectives about others social identities (i.e.,: race/ethnicity, gender, social class/socioeconomic status, sexual orientation, (dis)abilities, and religion). - Recognize the impact of conscious and unconscious assumptions, preconceptions, biases, and prejudices on the mentor-mentee relationship and acquire skills to manage them.- Identify concrete strategies for learning about others social identities and improving mentor-mentee relationships through culturally responsive mentoring.
- Keyword:
- NUCATS, Mentoring
- Subject: MESH:
- Mentoring, Mentors, Cultural Competency, Social Identification
- Creator:
- McGee, Rick, Kandula, Namratha R
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-01-13
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Presentation
- Title:
- Abstract - Development of a Graph Model for the OMOP Common Data Model
- Abstract:
- Current phenotyping and systems biology research requires not only integration of large volumes of Electronic Health Record (EHR) and multi-omics data, but also capturing the multitudes of relations among the concepts. Graph databases have emerged as a promising technology for such tasks, supporting not only local analysis but also global analysis leveraging graph algorithms like Centrality, Community Detection, Path Finding or Node Embeddings.Unfortunately, EHR data is rarely available in a graph format. While a nave row-to-node conversion is possible, the resulting graph is typically attribute-heavy, resulting in suboptimal performance. To address this limitation, we developed a modelling method to convert data form the Observational Medical Outcomes Partnership Common Data Model (OMOP CDM) to the Neo4j [www.neo4j.com] graph property model.
- Keyword:
- Graph Database, SCRIPT study, OMOP CDM
- Subject: MESH:
- Models, Theoretical
- Subject: LCSH:
- Graph databases
- Creator:
- Kang, Mengjia, Alvarado-Guzman, Jose A., Rasmussen, Luke, Starren, Justin B
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Abstracts
- Title:
- Development of a Graph Model for the OMOP Common Data Model
- Keyword:
- Graph Database, OMOP CDM, Graph schema, SCRIPT study, SCRIPT project, Neo4j
- Subject: MESH:
- Models, Theoretical
- Subject: LCSH:
- Graph databases
- Creator:
- Kang, Mengjia, Rasmussen, Luke, Starren, Justin B, Alvarado-Guzman, Jose A
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Poster
- Title:
- Defining in-field overeating: A scoping review
- Abstract:
- Objectives: This scoping review aims to broadly identify how overeating is defined and employed in real-world experimental and observational settings, as well as how overeating correlates to health outcomes. Specifically, we will review studies done in adult human populations. We will answer the following questions: How is overeating conceptually defined? (ex. overconsumption of calories vs. macronutrients, timing/skipping of meals, association with emotional or mental health state, etc.) What thresholds define overeating? (ex. number of calories/calories from a specific macronutrient, specific number of meals exceeded, definition of snacking, specific emotional or mental health factors etc.) What, if any, evidence exists that certain thresholds are more/less valid? What tools are used to measure eating/overeating? (self-reported vs researcher-guided recall, sensor data, food diary/data entry etc.) How does overeating in the real world correlate to health outcomes?
- Keyword:
- overeating, scoping review, protocol
- Subject: MESH:
- Eating, Hyperphagia
- Creator:
- Hussain, Tasmeen, Stump, Tammy Kay, Wafford, Q. Eileen, Alshurafa, Nabil
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Study Design
- Title:
- 2021-2022 Series 02 NUCATS Work-Life Integration
- Description:
- Explores different ways to conceptualize the intersection of important domains in our lives (e.g. work-life integration vs. work-life balance vs. an integrated life). Identifies priorities and goals for integrating these important domains both at work and outside of work. Discusses the challenges and opportunities related to our current remote working environment, and how this can be leveraged to achieve a more integrated life.
- Keyword:
- NUCATS, Mentoring
- Subject: MESH:
- Mentoring, Mentors, Work-Life Balance
- Creator:
- Allen, Norrina Bai, O'Brien, Matthew James
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-11-11
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Presentation
- Title:
- Mapping the OMOP Common Data Model to Neo4j for Pneumonia Therapy Response: SCRIPT Case Study
- Keyword:
- Graph Database, OMOP CDM, Graph Model, SCRIPT
- Subject: MESH:
- Pneumonia--therapy, Data Analysis
- Creator:
- Kang, Mengjia, Rasmussen, Luke
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Rights:
- All rights reserved
- Resource Type:
- Presentation
- Title:
- 2021-2022 Series 01 NUCATS Establishing and Aligning Expectations
- Description:
- In this workshop presentation, viewers will: Examine existing expectations in your current mentoring relationships; question which expectations need to be revisited or discussed. Recognize and describe how one can apply a variety of tools to promote alignment in mentoring relationships. Choose 1-2 behavior changes you can enact in the next 3-6 months to improve alignment in your mentoring relationships.
- Keyword:
- Mentoring, NUCATS
- Subject: MESH:
- Mentoring, Mentors
- Creator:
- Cameron, Kenzie A, Carnethon, Mercedes R
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-10-14
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Presentation
- Title:
- Recent advances in gene therapy for atrial fibrillation
- Original Bibliographic Citation:
- Yoo S, Geist GE, Pfenniger A, Rottman M, Arora R. Recent advances in gene therapy for atrial fibrillation. J Cardiovasc Electrophysiol. 2021;32:28542864.
- Abstract:
- Atrial fibrillation (AF) is the most common heart rhythm disorder in adults and a major cause of stroke. Unfortunately, current treatments for AF are suboptimal as they are not targeting the molecular mechanisms underlying AF. In this regard, gene therapy is emerging as a promising approach for mechanismbased treatment of AF. In this review, we summarize recent advances and challenges in gene therapy for this important cardiovascular disease.
- Keyword:
- Gene Therapy, Atrial Fibrillation
- Subject: MESH:
- Atrial Fibrillation, Genetic Therapy
- Creator:
- Rottmann, Markus, Yoo, Shin, Geist, Gail Elizabeth, Pfenniger, Anna, Arora, Rishi K
- Publisher:
- Journal of Cardiovascular Electrophysiology, DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-05-30
- Rights:
- All rights reserved
- Resource Type:
- Journal Article
- Original Identifier:
- (DOI) 10.1111/jce.15116
- Title:
- Mental health interventions for young people delivered through social media: Protocol for a scoping review
- Abstract:
- Objectives: The objective of this scoping review is to identify and review empirical research on social media-based interventions aimed at improving mental health conditions in adolescents and young adults. Sincesocial media is a consistently evolving term, a secondary objective of this review is to identify thequalities of platforms labeled as social media. We limit the scope of interventions to those that are entirely, or mostly, delivered through social media and to studies examining the intentional implementation of a mental health intervention (excluding naturalistic intervention, peer support).
- Keyword:
- scoping review, protocol
- Subject: MESH:
- Social Media, Social Networking, Mental Health, Child, Adolescent, Health Promotion
- Creator:
- Kruzan, Kaylee P, Williams, Kofoworola DA, Meyerhoff, Jonah, O'Dwyer, Linda, Mohr, David C, De Choudhury, Munmun, Yoo, Dong Whi
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Rights:
- http://creativecommons.org/licenses/by-nc/3.0/us/
- Resource Type:
- Study Design
- Title:
- Navigating the Road Ahead (The 21st Health Sciences Lively Lunchtime Discussion)
- Description:
- Handout prepared for a brief (traditional) annual update of interesting and noteworthy trends in the health publishing and health information sectors that occurred or were noticed since the 2020 Health Sciences Lively Lunch at the Charleston Conference: Issues in Book and Serial Acquisition. (the 21st Lively Lunch took place on Thursday, November 4, 2021 in a hybrid fashion).
- Keyword:
- Charleston Conference
- Subject: MESH:
- Libraries, Medical
- Subject: LCSH:
- Scholarly publishing
- Creator:
- Kubilius, Ramune K.
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-10-21
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Presentation
- Title:
- Return to work model after injury or illness: A Scoping Review Protocol
- Abstract:
- After injury or illness, return to work (RTW) is important for previously-employed patients, and is positively associated with functional recovery and economic status.1-5 Failure to return to work (RTW) following illness or injury is often, both theoretically and operationally, equated with work disability.6 In the past three decades, biomedical, social construction, and biopsychosocial models have proposed to describe the process and potential factors that influence human responses to work and the development of work disability. 7 Within the biomedical perspective, disability is produced by a medical condition, which deviates individuals from normal biomedical function or structure. 6 8 Factors such as context and environment are not considered. However, in the social construction paradigm, disability is viewed as a combination of activities, relationships, individual attributes, and conditions arising mainly from the social environment.8 Thus, disability depends on a societal response in a given context. The biopsychosocial models approach disability from both the social and the biomedical paradigms, which provide the most comprehensive view to discuss work disability. From the biopsychosocial point of view, multiple factors potentially affect RTW. The occupational disability model, which includes medical status (such as neurologic, cardiovascular), physical capability (physical status, work tolerance), work demands (biomechanical, psychological), and psychological/behavioral resources (workers traits, psychological readiness), is an example of an early biopsychosocial approach.9 Many other models have been proposed to understand RTW from the biopsychosocial approach, such as the Institute of Medicine model of disability,10 the International Classification of Functioning, Disability, and Health (ICF)/the expanded ICF model,11 the cancer and work model,12 as well as the readiness for return to work model. The scoping review aims to 1) identify existing RTW models using biopsychosocial approach, 2) compare and contract these models, and 3) synthesis these models and proposed a comprehensive model.
- Keyword:
- scoping review, model, return to work, protocol
- Subject: MESH:
- Return to Work, Rehabilitation, Vocational
- Creator:
- Su, Han, Park, Mirang, Thompson, Hilaire J., O'Dwyer, Linda
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-10-21
- Rights:
- All rights reserved
- Resource Type:
- Review
- Title:
- Evaluating Current Practices in Primary Care Pediatrics Education: A Scoping Review Protocol
- Abstract:
- As methods and research in the field of medical education are constantly growing and evolving, new practices in teaching are being applied to multiple specialties and subspecialties across medicine, including pediatrics. The field of primary care pediatrics is one that encompasses a wide breadth of information, and given the ever-changing landscape of medical education, evaluation of recent changes or developments in how primary care pediatrics is taught at the resident physician and medical student level could help to identify areas for further improvement. In order to identify recent changes in the way that primary care pediatrics teaching occurs and what areas could be improved, we ask the question: what qualitative, quantitative, or mixed-methods research exists regarding primary care pediatrics education for medical students and resident trainees?
- Keyword:
- scoping review, primary care, pediatrics
- Subject: MESH:
- Pediatrics--education, Physicians, Primary Care--education
- Creator:
- Bruton, Lucas Baughn, Quadri, Maheen, O'Dwyer, Linda
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-09
- Rights:
- All rights reserved
- Resource Type:
- Review
- Title:
- Vanoye KCNQ2 data tables Oct 15, 2021
- Description:
- These are data tables in Excel format to accompany submission of an article entitled: High-throughput Evaluation of KCNQ2 Variants Reveals Functional and Pharmacological Heterogeneity
- Original Bibliographic Citation:
- Pending
- Abstract:
- Hundreds of KCNQ2 variants have been identified by genetic testing of children with early onset epilepsy and/or developmental disability. Voltage-clamp recording from heterologous cells has proved useful for establishing deleterious functional effects of KCNQ2 variants, but procedures adapting these assays for standardized, higher throughput data collection and reporting are lacking. In this study, we employed automated patch clamp recording to assess in parallel the functional and pharmacological properties of 79 missense and 2 in-frame deletion variants of KCNQ2. Among the variants we studied were a training set of 18 pathogenic variants previously studied by voltage-clamp recording, 24 mostly rare population variants, and 39 disease-associated variants with unclear functional effects. Variant KCNQ2 subunits were transiently expressed in a cell line stably expressing KCNQ3 to reconstitute the physiologically relevant channel complex. Variants with severe loss-of-function were also co-expressed 1:1 with WT KCNQ2 in the KCNQ3 cell line to mimic the heterozygous genotype and assess dominant-negative behavior. In total, we analyzed electrophysiological data recorded from 9,480 cells. The functional properties of WT KCNQ2/KCNQ3 channels and pharmacological responses to known blockers and activators determined by automated patch clamp recording were highly concordant with previous findings. Similarly, functional properties of 18 known pathogenic variants largely matched previously published results and the validated automated patch clamp assay. Many of the 39 previously unstudied disease-associated KCNQ2 variants exhibited prominent loss-of-function and dominant-negative effects, providing strong evidence in support of pathogenicity. All variants, exhibit response to retigabine (10 M), although there were differences in maximal responses. Variants within the ion selectivity filter exhibited the weakest responses whereas retigabine had the strongest effect on gain-of-function variants in the voltage-sensor domain. Our study established a high throughput method to detect deleterious functional consequences of KCNQ2 variants. We demonstrated that dominant-negative loss-of-function is a common mechanism associated with missense KCNQ2 variants but this does not occur with rare population variation in this gene. Importantly, we observed genotype-dependent differences in the response of KCNQ2 variants to retigabine.
- Keyword:
- KCNQ2, Vanoye
- Creator:
- George Jr., Alfred L.
- Contributor:
- Vanoye, Carlos Guillermo
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Date Created:
- October 17, 2021
- Rights:
- http://creativecommons.org/licenses/by-nc/3.0/us/
- Title:
- Health Sciences eBooks in 2021: Availability, Challenges, and Trends
- Description:
- Originally published in: Kubilius, Ramune K. and Butzen-Cahill, Tim. Health Sciences Books in 2021: Availability, Challenges, and Trends. Against the Grain. 2021; 33(4):14-16. https://www.charleston-hub.com/2021/09/health-sciences-ebooks-in-2021-availability-challenges-and-trends. PDF of article posted with publisher's permission.
- Original Bibliographic Citation:
- Kubilius, Ramune K. and Butzen-Cahill, Tim. Health Sciences Books in 2021: Availability, Challenges, and Trends. Against the Grain. 2021; 33(4):14-16. https://www.charleston-hub.com/2021/09/health-sciences-ebooks-in-2021-availability-challenges-and-trends.
- Keyword:
- ebooks, e-books
- Subject: MESH:
- Libraries, Medical
- Subject: LCSH:
- Collection development (Libraries), Books
- Creator:
- Kubilius, Ramune K., Butzen-Cahill, Tim
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-09
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Title:
- Holistic Thinking in Collections and Collection Development
- Description:
- Poster talk presented during the Health Sciences Librarians of Illinois (HSLI) virtual conference on October 27, 2021.
- Abstract:
- Libraries' sizes and organizational structures differ when it comes to assignment of official responsibilities for collection development and management. Publisher and vendor questionnaires ask whether one has final responsibility or an advisory role in decision-making. An argument can be made that we all can and should have a role in knowing about and providing information resources for our primary users, no matter our official job responsibilities. And more. Especially in today's scholarly communications and publishing landscape. A few use cases will be shared that make the argument that we all have access to and can take advantage of various opportunities- to monitor, watch, be informed about, act on, or "connect the dots" in health sciences collections-related work, in our libraries, in our parent institutions, and professionally. As new publishing trends bring new resources to the forefront, many that are free, traditional print collections and online subscriptions no longer should limit our definitions of collections-related work. Official duties and job titles should not limit us from thinking and acting holistically, in order to also take advantage of opportunities provided by interim responsibilities, committees and working groups. The objective is to look for interconnections, share and repurpose work, where possible, and to think holistically.
- Keyword:
- collection development
- Subject: MESH:
- Libraries, Medical
- Subject: LCSH:
- Collection development (Libraries), Scholarly publishing
- Creator:
- Kubilius, Ramune K.
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-10-27
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Poster