Investigators at Pitie-Salpetriere and Robert Debre Hospitals, and other centers in France, evaluated consecutive patients referred for suspected Kleine-Levin (KLS) syndrome, detailed differential diagnoses, and examined characteristics of patients with prolonged (>30 days) episodes.
Structural Connectivity in Gilles de la Tourette Syndrome
Investigators from Centre de Reference National Maladie Rare Syndrome Gilles de la Tourette and Sorbonne University report white matter abnormalities in the pathways connecting the cerebral cortex, basal ganglia, and thalamus in a group of 49 adults with Tourette syndrome (TS).
Tractography, Structural Connectivity, Cortico-Basal Ganglia Networks, Gilles de la Tourette Syndrome
Neurology, Infant, Pediatrics, Nervous System Diseases, Movement Disorders, Child Development, Brain Diseases, Neurosurgery, Child
Chelse, Ana B., Blackburn, Joanna S.
DigitalHub. Galter Health Sciences Library, Pediatric Neurology Briefs Publishers
Researchers at Okayama University, Japan showed lactate dehydrogenase (LDH) inhibition suppresses neuronal excitation in vitro, reduces EEG discharges and seizures in rodent models, and may provide a novel mechanism for anticonvulsant medications in human patients.
Investigators from New York Presbyterian Morgan Stanley Children's Hospital examined whether having an isolated headache following minor blunt head trauma was suggestive of traumatic brain injury (TBI) among a large cohort of children 2-18 years of age.
Blunt Head Trauma, Headache, Traumatic Brain Injury
Investigators from New York University, NY, studied 14 patients with congenital insensitivity to pain with anhidrosis (CIPA), compared to 10 patients with chronically deficient sympathetic activity (pure autonomic failure), and 15 normal age-matched controls.
Clinical Features of Infectious and Autoantibody Encephalitis
Investigators from University of Sydney, Australia; John Radcliffe Hospital, Oxford, UK; Imperial College, London, UK; and other centers, studied infectious, immune-mediated/autoantibody associated and unknown forms of encephalitis, including frequencies, clinical and radiological phenotypes, and long-term outcome.
Investigators from the Division of Emergency Medicine, Sports Medicine, and Department of Pediatrics, Children's Hospital of Philadelphia, PA, and Sports Medicine, Somerset, NJ, performed a retrospective cohort study of 247 patients ages 5-18 years with concussion referred from July 2010 to Dec 2011; 81% of patients showed a vestibular abnormality on initial clinical examination.