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- Title:
- Protocol Scoping Review Communication and Feeding with DYRK1A 2023
- Abstract:
- Structured Summary: We seek to develop a comprehensive report of communication andfeeding skills for children/persons with DYRK1A which has been documented acrossstudies. We will search multiple databases and include articles/evidence based on humanparticipants.
- Keyword:
- DYRK1A, Communication, Feeding
- Subject: MESH:
- Feeding Behavior
- Creator:
- Pitts, Laura LeRette, Wafford, Q. Eileen, Brennecke, Grace, Hirsch, Hailey
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2023-03-07
- Rights:
- http://creativecommons.org/licenses/by-nc-nd/3.0/us/
- Resource Type:
- Study Design
- Title:
- Scoping Review of Neuromonitoring practices for neonates with congenital heart disease
- Description:
- Protocol for Scoping Review of Neuromonitoring in Neonates with Congenital Heart Disease
- Abstract:
- We seek to synthesize the known literature for neuromonitoring with EEG, aEEG, NIRS, transcranial doppler (TCD) and other multimodal neuromonitoring techniques for neonates with congenital heart disease to clarify current practices, document available studies, investigate gaps in research that may inform the care of this population.
- Keyword:
- Congenital heart disease, Neonatal, Neuromonitoring
- Subject: MESH:
- Heart Defects, Congenital, Infant, Newborn, Diagnostic Techniques, Neurological
- Creator:
- Pardo, Andrea Catalina
- Contributor:
- Nunes, Denise A, Carrasco, Melisa, Gano, Dawn, Chau, Vann, Chock, Valerie, Wintermark, Pia, Sen, Shawn K, Wusthoff, Courtney J
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2023-03-08
- Rights:
- All rights reserved
- Resource Type:
- Study Design
- Title:
- Search Strategies for a Systematic Review of Keloid Treatments
- Keyword:
- systematic review, search strategy, search query, search queries, search strategies, keloid, keloids
- Subject: MESH:
- Keloid, Research Design
- Subject: LCSH:
- Database searching
- Creator:
- Walsh, Laura Aiko, Wu, Ellen, Pontes, David, Kwan, Kevin, Poondru, Sneha, Miller, Corinne H, Kundu, Roopal V
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2020-11-24
- Rights:
- http://creativecommons.org/licenses/by-sa/3.0/us/
- Resource Type:
- Electronic Supplementary Materials
- Title:
- The Use of Patient-Reported Outcome Measures (PROMs) for Care of People with Cardiovascular Disease in African Countries A Scoping Review Protocol
- Abstract:
- The persistence of poor healthcare outcomes from cardiovascular disease has caused a shift towards measuring patientreported outcomes (PROMs) as a method to improve quality of care. Some patientreported outcomes have been associated with improved mortality and readmission-rates; however, the majority of research in this field originates from high-income and/or nonAfrican countries.This protocol is for a scoping review of the current use of PROMs in care of patients with cardiovascular disease within African countries. The goal of this review is to determine the extent of published literature on the measurement and use of PROMs for cardiovascular care within Africa. In doing this, the aim is to identify: strengths and weaknesses in PROM use, barriers and assets into implementation, the pool of PROM tools in use in the setting, and gaps in the current literature.Eligible studies will have at least one study site located in an African country and use a PROM in clinical care or research of patients with any of the following primary cardiovascular diseases: coronary artery disease, heart failure, arrhythmias, cardiomyopathy, and/or congenital heart disease. Examples of patientreported outcome measures include: symptoms, functional status, depression, selfefficacy, ADLs.Methods: The search will utilize seven databases, searching from the earliest available article until the day of the final search. Each title/abstract will be screened by two reviewers, with a third reviewer serving as a tie-breaker in the case of a disagreement about the inclusion criteria. Articles which make it past the titles/abstract screen will moved to the full text review. During this phase, relevant evidence from each article will be charted on an excel sheet. Results will categorized and published in a per-reviewed manuscript.
- Keyword:
- patient-centered care, patient-reported outcome, patient voice, cultural adaptation, Africa
- Subject: MESH:
- Cardiovascular Diseases, Patient Reported Outcome Measures
- Subject: Geographic Name:
- Africa
- Creator:
- Akanyirige, Precious, Mensah, Cheryl Nicole, Holder, Kai, Beestrum, Molly, Mlay, Jackson, Chillo, Pilly, Kaaya, Sylvia, Hawkins, Claudia, Hirschhorn, Lisa Ruth
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Rights:
- All rights reserved
- Resource Type:
- Study Design
- Title:
- 2022-2023 Series 04 NUCATS Strategic Mentoring: Using Mentoring Families for Increased Benefit
- Keyword:
- NUCATS, Mentoring, Mentoring Families, Mentor
- Subject: MESH:
- Mentoring
- Creator:
- Peigh, Graham Spencer, Passman, Rod S
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-02-22
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Presentation
- Title:
- Immigrant Health Filter Datasets
- Keyword:
- search filters, immigrant health, data extraction forms, dataset
- Creator:
- Wafford, Q. Eileen, Miller, Corinne H, Wescott, Annie B, Kubilius, Ramune
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Rights:
- http://creativecommons.org/licenses/by-nd/3.0/us/
- Resource Type:
- Dataset
- Title:
- 2-Immigrant-Culture-Language-Ethnicity Terms from Terms ID-Extraction-Process
- Keyword:
- search filters, immigrant health, data extraction forms, filter
- Creator:
- Wafford, Q. Eileen, Miller, Corinne H, Wescott, Annie B, Kubilius, Ramune
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Rights:
- http://creativecommons.org/licenses/by-nc/3.0/us/
- Resource Type:
- Dataset
- Title:
- 1-Terms Identification from Development Set References
- Keyword:
- search filters, immigrant health, data extraction forms, filter
- Creator:
- Wafford, Q. Eileen, Miller, Corinne H, Wescott, Annie B, Kubilius, Ramune
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Rights:
- http://creativecommons.org/licenses/by-nc/3.0/us/
- Resource Type:
- Dataset
- Title:
- 3-Term Identification and Testing Rank 1 and 2
- Keyword:
- search filters, immigrant health, data extraction forms, filter
- Creator:
- Wafford, Q. Eileen, Miller, Corinne H, Wescott, Annie B, Kubilius, Ramune
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Rights:
- http://creativecommons.org/licenses/by-nc/3.0/us/
- Resource Type:
- Dataset
- Title:
- 4-Rank 2 Term Testing
- Keyword:
- search filters, immigrant health, data extraction forms, filter
- Creator:
- Wafford, Q. Eileen, Miller, Corinne H, Wescott, Annie B, Kubilius, Ramune
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Rights:
- http://creativecommons.org/licenses/by-nc/3.0/us/
- Resource Type:
- Dataset
- Title:
- Immigrant Health PubMed Search Filters
- Description:
- Final, validated search filters for searching PubMed: immigrant-focused filter and immigrant-broad filter. Last updated November 2022. Developed by: Q. Eileen Wafford, MSt, MLIS, AHIP; Corinne Miller, MLIS; Annie Wescott, MLIS; Ramune K. Kubilius, MALS, AHIP
- Original Bibliographic Citation:
- Citation: Wafford QE, Miller CH, Wescott AB, Kubilius RK. Immigrant Health PubMed Search Filters. Galter Health Sciences Library and Learning Center. 2022 Nov.
- Keyword:
- search filters, filter, search strategy, literature search, immigrant health
- Subject: MESH:
- Emigrants and Immigrants, Refugees, PubMed, Delivery of Health Care, Health Disparate, Minority and Vulnerable Populations
- Subject: LCSH:
- Searching, Bibliographical, Emigrants, Immigrants, Refugees
- Creator:
- Wafford, Q. Eileen, Miller, Corinne H, Wescott, Annie B, Kubilius, Ramune
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-11
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Other
- Title:
- Quantitative approaches for the evaluation of implementation research studies
- Original Bibliographic Citation:
- Justin D. Smith and Mohamed Hasan, Psychiatry Research, https://doi.org/10.1016/j.psychres.2019.112521
- Abstract:
- Implementation research necessitates a shift from clinical trial methods in both the conduct of the study and in the way that it is evaluated given the focus on the impact of implementation strategies. That is, the methods or techniques to support the adoption and delivery of a clinical or preventive intervention, program, or policy. As strategies target one or more levels within the service delivery system, evaluating their impact needs to follow suit. This article discusses the methods and practices involved in quantitative evaluations of implementation research studies. We focus on evaluation methods that characterize and quantify the overall impacts of an implementation strategy on various outcomes. This article discusses available measurement methods for common quantitative implementation outcomes involved in such an evaluationadoption, fidelity, implementation cost, reach, and sustainmentand the sources of such data for these metrics using established taxonomies and frameworks. Last, we present an example of a quantitative evaluation from an ongoing randomized rollout implementation trial of the Collaborative Care Model for depression management in a large primary healthcare system.
- Keyword:
- Implementation measurement, Implementation research, Summative evaluation
- Subject: MESH:
- Implementation Science
- Creator:
- Hasan, Mohamed Mosaad Ismail, Smith, J.D.
- Publisher:
- Elsevier, DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2020-01
- Rights:
- All rights reserved
- Resource Type:
- Journal Article
14. Disaster and Mass Casualty Incident Responses by Intensive Care Units: A Scoping Review Protocol
- Title:
- Disaster and Mass Casualty Incident Responses by Intensive Care Units: A Scoping Review Protocol
- Description:
- An a priori scoping review protocol submission to the Northwestern DigitalHub (an institutional repository for the research and scholarly output of Northwestern Medicine) following Preferred Reporting Items for Systematic Review and Meta-analysis Protocols.
- Abstract:
- Critical care has displayed an interest in the field of disaster and mass casualty incident response (2). A disaster refers to a man-made or natural event requiring resources from outside a local community to return to pre-event status (3). An incident occurs secondary to similar hazards, requiring an emergency response to protect life, however, may not require resources from outside a local community (4). A mass casualty incident focuses on healthcare system capacity, where casualties rapidly exceed capabilities (5). Here we focus on the timeframe of acute response by intensive care units (ICUs) themselves: a relief phase - where lifesaving and mitigation efforts dominate - and a subsequent recovery phase - where efforts return systems to pre-event status. Significant infrastructure, personnel and equipment resources are required to operate ICUs (6). Disasters and mass casualty incidents are known to result in an influx of critically ill patients (2). Thus, ICU populations must be thought of as especially at risk.Yet, there remains a paucity of well-compiled data from the front-lines of ICU response initiatives, hampering evidence-based guideline production (2). Disaster research theory, though, is well-established (3). Categorical, continuous, or even narrative data reported by responders in the midst of response initiatives represent evidence (7). It is possible that through initial publication and valuating of such reports, we may illuminate intervention effects, variation in experience and practice, and identify gaps and inconsistencies in the literature.The purpose of this scoping review will be to compile and analyze ICU disaster and mass casualty incident response experiences. We intend to characterize ICU experiences - reported by ICUs themselves - to organize quantitative and qualitative data. Quantitative data, in the form of categorical and continuous items reported, will be assessed. Qualitative analyses will be undertaken through narrative inquiry of anecdotes. Outcomes of interest include identification of trends, analyses of existing reports for consistency, typical experience strengths or weaknesses, lessons learned, and best practices. This scoping review represents the first published data compilation and analysis of ICU disaster and mass casualty incident response initiatives.
- Keyword:
- Disaster, Mass casualty, Incident, Critical care, Intensive care unit, Response
- Subject: MESH:
- Mass Casualty Incidents, Intensive Care Units, Critical Care
- Creator:
- Moffet, Eric Warren
- Contributor:
- Wescott, Annie B
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2023-01-23
- Rights:
- All rights reserved
- Resource Type:
- Review
- Title:
- An umbrella review comparing computer-assisted and conventional total joint arthroplasty: quality assessment and summary of evidence
- Original Bibliographic Citation:
- Hasan MM, Zhang M, Beal M, et al. An umbrella review comparing computer-assisted and conventional total joint arthroplasty: quality assessment and summaryof evidence. BMJ Surg Interv Health Technologies2020;2:e000016. doi:10.1136/bmjsit-2019-000016
- Abstract:
- Background Systematic reviews (SRs) of computer-assisted (CA) total knee arthroplasty (TKA) and total hip arthroplasty (THA) report conflicting evidence on its superiority over conventional surgery. Little is known about the quality of these SRs; variability in their methodological quality may be a contributing factor. We evaluated the methodological quality of all published SRs to date, summarized and examined the consistency of the evidence generated by these SRs.Methods We searched four databases through December 31, 2018. A MeaSurement Tool to Assess systematic Reviews 2 (AMSTAR 2) was applied to assess the methodological quality. Evidence from included meta-analyses on functional, radiological and patient-safety outcomes was summarized. The corrected covered area was calculated to assess the overlap between SRs in including the primary studies.Results Based on AMSTAR 2, confidence was critically low in 39 of the 42 included SRs and low in 3 SRs. Low rating was mainly due to failure in developing a review protocol (90.5%); providing a list of excluded studies (81%); accounting for risk of bias when discussing the results (67%); using a comprehensive search strategy (50%); and investigating publication bias (50%). Despite inconsistency between SR findings comparing functional, radiological and patient safety outcomes for CA and conventional procedures, most TKA meta-analyses favored CA TKA, whereas most THA meta-analyses showed no difference. Moderate overlap was observed among TKA SRs and high overlap among THA SRs.Conclusions Despite conclusions of meta-analyses favoring CA arthroplasty, decision makers adopting this technology should be aware of the low confidence in the results of the included SRs. To improve confidence in future SRs, journals should consider using a methodological assessment tool to evaluate the SRs prior to making a publication decision.
- Keyword:
- overview of systematic review, total joint arthroplasty, computer-assisted surgery, meta-analysis
- Subject: MESH:
- Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip, Surgery, Computer-Assisted
- Creator:
- Hasan, Mohamed Mosaad Ismail, Zhang, Manrui, Beal, Matthew, Ghomrawi, Hassan
- Publisher:
- BMJ Journals
- Language:
- English
- Date Created:
- 2020
- Rights:
- http://creativecommons.org/licenses/by-nc/3.0/us/
- Resource Type:
- Journal Article
- Title:
- Is there variation in utilization of preoperative tests among patients undergoing total hip and knee replacement in the US, and does it affect outcomes? A population-based analysis
- Original Bibliographic Citation:
- Hasan, M.M., Kang, R., Lee, J. et al. Is there variation in utilization of preoperative tests among patients undergoing total hip and knee replacement in the US, and does it affect outcomes? A population-based analysis. BMC Musculoskelet Disord 23, 972 (2022). https://doi.org/10.1186/s12891-022-05945-y
- Abstract:
- Study objectiveTo describe recent practice patterns of preoperative tests and to examine their association with 90-day all-cause readmissions and length of stay.DesignRetrospective cohort study using the New York Statewide Planning and Research Cooperative System (SPARCS).SettingSPARCS from March 1, 2016, to July 1, 2017.ParticipantsAdults undergoing Total Hip Replacement (THR) or Total Knee Replacement (TKR) had a preoperative screening outpatient visit within two months before their surgery.InterventionsElectrocardiogram (EKG), chest X-ray, and seven preoperative laboratory tests (RBCs antibody screen, Prothrombin time (PT) and Thromboplastin time, Metabolic Panel, Complete Blood Count (CBC), Methicillin Resistance Staphylococcus Aureus (MRSA) Nasal DNA probe, Urinalysis, Urine culture) were identified.Primary and secondary outcome measuresRegression analyses were utilized to determine the association between each preoperative test and two postoperative outcomes (90-day all-cause readmission and length of stay). Regression models adjusted for hospital-level random effects, patient demographics, insurance, hospital TKR, THR surgical volume, and comorbidities. Sensitivity analysis was conducted using the subset of patients with no comorbidities.ResultsFifty-five thousand ninety-nine patients (60% Female, mean age 66.1+/9.8 SD) were included. The most common tests were metabolic panel (74.5%), CBC (66.8%), and RBC antibody screen (58.8%). The least common tests were MRSA Nasal DNA probe (13.0%), EKG (11.7%), urine culture (10.7%), and chest X-ray (7.9%). Carrying out MRSA testing, urine culture, and EKG was associated with a lower likelihood of 90-day all-cause readmissions. The length of hospital stay was not associated with carrying out any preoperative tests. Results were similar in the subset with no comorbidities.ConclusionsWide variation exists in preoperative tests before THR and TKR. We identified three preoperative tests that may play a role in reducing readmissions. Further investigation is needed to evaluate these findings using more granular clinical data.
- Keyword:
- Preoperative testing, Preoperative EKG, Total knee replacement, Total hip replacement, MRSA screening, Asymptomatic bacteriuria
- Subject: MESH:
- Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee, Preoperative Care, Patient Readmission, Length of Stay
- Subject: Geographic Name:
- New York (State)
- Creator:
- Hasan, Mohamed Mosaad Ismail, Kang, Raymond H, Lee, Julia, Beal, Matthew D, Ahmed, Abdalrahman G, Tian, Yao, Ghomrawi, Hassan
- Publisher:
- Springer Nature
- Language:
- English
- Date Created:
- 2022-11-10
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Journal Article
- Title:
- NO WAIT: new organised well-adapted immediate triage: a lean improvement project
- Original Bibliographic Citation:
- Elkholi A, Althobiti H, Al Nofeye J, et al. NO WAIT: new organised well-adapted immediate triage: a lean improvement project. BMJ Open Quality 2021;10:e001179. doi:10.1136/bmjoq-2020-001179
- Abstract:
- Long waiting times in the emergency department (ED) are associated with decreased patient satisfaction and increased morbidity and mortality. Triage may be a contributing factor to prolonged wait times in the ED. At Alhada Armed Forces Hospital (Taif, Saudi Arabia), patients other than level 1 and 2 on the Canadian Triage and Acuity Scale are requested to wait until triage. During peak hours (08:0022:00), the waiting time prior to triage is prolonged, and several patients leave the ED before triage. In this project, a multidisciplinary team was assembled to revise patient flow from the time of arrival at the ED to the time of triage. Lean methodology was used to identify the redundancies and design a seamless flow process for ED patients. Through reorganising the triage area using minimal additional resources, the project team devised a novel floor plan for the triage area which provided a unique patient flow in the ED. The median patient wait time from arrival to triage was reduced from 27 min to 4.09 min and the percentage of patients leaving the ER before triage was reduced to 0%. This project is the first of its kind in Saudi Arabia, as well as in the Gulf region, and provides a radical solution to the problem of patient waiting in the ED during peak hours.
- Keyword:
- Quality Improvement, Lean, Emergency Department, Alhada Armed Forces Hospital
- Subject: MESH:
- Emergency Service, Hospital, Triage, Time-to-Treatment
- Subject: Geographic Name:
- Taif (Saudi Arabia)
- Creator:
- Hasan, Mohamed Mosaad Ismail, Elkholi, Ahmed, Althobiti, Huda, Al Nofeye, Jamal
- Publisher:
- BMJ Journals
- Language:
- English
- Date Created:
- 2021
- Rights:
- http://creativecommons.org/licenses/by-nc/3.0/us/
- Resource Type:
- Journal Article
- Title:
- 2022-2023 Series 02 NUCATS Articulating your Mentoring Philosophy and Plan
- Keyword:
- NUCATS, Mentoring , Mentoring Philosophy, Mentoring Plan, Northwestern Center for Leadership
- Subject: MESH:
- Mentoring
- Creator:
- Goodman, Adam
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-11-09
- Rights:
- http://creativecommons.org/licenses/by-nc/3.0/us/
- Resource Type:
- Presentation
- Title:
- Medical Oncology Education for Medical Students - Where do we stand? A scoping review protocol for updating a literature review
- Keyword:
- Medical Oncology Education, Medical Student Education, Undergraduate Medical Education, Oncology, Medical Oncology, Medical Student Training
- Subject: MESH:
- Education, Medical, Undergraduate, Medical Oncology
- Creator:
- Theros, Jonathan Spero, Fuchs, Jeffrey William, Nunes, Denise A, Fuchs, Joseph Robert
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Rights:
- All rights reserved
- Resource Type:
- Review
- Title:
- Northwestern University Medical School 1859-1979
- Description:
- A history of the Feinberg School of Medicine, written by Leslie B. Arey, PhD, a faculty member in the Department of Anatomy from 1919 to 1987.
- Keyword:
- History
- Subject: MESH:
- History, Schools, Medical
- Subject: Geographic Name:
- Chicago (Ill.)
- Subject: Name:
- Northwestern University (Evanston, Ill.). Medical School
- Creator:
- Arey, Leslie Brainerd, 1981 -
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 1979
- Rights:
- All rights reserved
- Resource Type:
- Book
- Title:
- Down Long Wiggled Roads: Familiar and New Health Sciences Information Places (22nd Health Sciences Lively Lunchtime Discussion): Developments 2021-2022
- Description:
- Compilation includes: 1) Handout, prepared for and presented in synopsis during a brief (traditional) annual update of interesting and noteworthy trends in the health publishing and health information sectors that occurred or were noticed since the 2021 Health Sciences Lively Lunch at the Charleston Conference: Issues in Book and Serial Acquisition. 2-4) Session presentation slides of: Sarah McClung (University of San Francisco Library), Andrea McLennan (McMaster University Health Sciences Library), and Karen Gau (Virginia Commonwealth University Libraries). (The 22nd Lively Lunch took place on Wednesday, November 2, 2022 in Charleston, SC and was repeated during virtual week on November 16, 2022).
- Keyword:
- Charleston Conference, DEIA, VR, DEI, Grants
- Subject: MESH:
- Libraries, Medical, Virtual Reality, Medical Library Association, Library Collection Development, Cultural Diversity
- Subject: LCSH:
- Scholarly publishing, Grants-in-aid, Collection development (Libraries), Collection management (Libraries)
- Creator:
- Kubilius, Ramune K., McClung, Sarah, McLellan, Andrea, Gau, Karen
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Charleston, South Carolina, United States
- Language:
- English
- Date Created:
- 2022-11-02
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Presentation
23. Surveying the Medical IR Landscape for Presentations or Publication: Challenges and Opportunities
- Title:
- Surveying the Medical IR Landscape for Presentations or Publication: Challenges and Opportunities
- Description:
- Lightning talk for the Medical Repositories in Libraries (MIRL) virtual symposium, November 17, 2022.
- Abstract:
- The medical institutional repository landscape is ever evolving and presents challenges for anyone who wishes to research it for presentation or publication. Librarians are one of the central stakeholders in the medical IR world, but not all librarians may be equally immersed in this area. Those who are directly involved may research and report on use cases and institution or platform-specific IR scenarios. Yet, it can be argued that in many instances, there is an important reason for introductory material on the world of repositories, in providing background and context. No matter one's job title or responsibilities, there are opportunities to become involved in exploring the world of repositories- for internal work at an institution, or externally in professional work. Contributions can vary: doing background research, providing introductory slides (on statistics, platforms, aspirational IRs to examine, other information) for an in-service workshop for colleagues, identifying and seeking out colleagues who can contribute expertise for professional collaborative research, publication, or presentation projects. Based on examples from the past half dozen years, this presentation consists of some sources, tips, and caveats for those who might be called upon to be part of the work involved in surveying the world of medical institutional repositories.
- Keyword:
- IR, MIRL, Medical Institutional Repositories in Libraries, Scholarly communication
- Subject: MESH:
- Libraries, Medical
- Subject: LCSH:
- Institutional repositories, Scholarly publishing
- Creator:
- Kubilius, Ramune K.
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-11-17
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Presentation
- Title:
- 2022-2023 Series 01 NUCATS Establishing and Aligning Expectations
- Keyword:
- NUCATS, Mentoring, Establishing Expectations, Aligning Expectations
- Subject: MESH:
- Mentoring, Mentors, Communication
- Creator:
- Cameron, Kenzie A, Liem, Robert I
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-10-12
- Rights:
- http://creativecommons.org/licenses/by-nc-nd/3.0/us/
- Resource Type:
- Presentation
- Title:
- Chicago Area Medical Archivists Medical History Symposium (2022)
- Description:
- Program of the CAMA Medical History Symposium that was held virtually on October 6, 2022.
- Keyword:
- CAMA, Program, Symposium
- Subject: MESH:
- Libraries, Medical, Archives, History of Medicine
- Subject: LCSH:
- Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Chicago Area Medical Archivists
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2022-10-06
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Programs
- Title:
- Chicago Area Medical Archivists Medical History Symposium (2006)
- Description:
- Program (draft version #2- final version not yet located) of the 5th CAMA Medical History Symposium that was co-sponsored with the National Archives on October 6, 2006 at National Archives and Records Administration-Great Lakes Region, Chicago, IL., Source: CAMA correspondence file housed at Rush University Medical Center Archives (used with permission). Draft schedule packet (not included here) includes correspondence among organizers and information about an event held after the CAMA symposium on October 6th- "Ask the Archivists" - A Chicago Area Archivists' Open House for History Researchers, Students, Educators, and Librarians.
- Keyword:
- CAMA, Program, Symposium
- Subject: MESH:
- Libraries, Medical, Archives, History of Medicine
- Subject: LCSH:
- Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Chicago Area Medical Archivists
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2006-10-06
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Programs
- Title:
- Chicago Area Medical Archivists Medical History Symposium (2002)
- Description:
- Program of the 1st CAMA Medical History Symposium that was held on October 24, 2002, hosted by the American Medical Association's Archives Department at the American Medical Association Headquarters, Chicago, IL.
- Keyword:
- CAMA, Program, Symposium
- Subject: MESH:
- Libraries, Medical, Archives, History of Medicine, History of Dentistry
- Subject: LCSH:
- Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Chicago Area Medical Archivists
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2002-10-24
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Programs
- Title:
- Chicago Area Medical Archivists Medical History Symposium (2004)
- Description:
- Program of the 3rd CAMA Medical History Symposium that was held on October 15, 2004 at Northwestern Memorial Hospital, Feinberg Pavilion Conference Rooms, Chicago, IL.
- Keyword:
- CAMA, Program, Symposium
- Subject: MESH:
- Libraries, Medical, Archives, History of Medicine, History of Nursing
- Subject: LCSH:
- Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Chicago Area Medical Archivists
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2004-10-15
- Rights:
- http://creativecommons.org/licenses/by-nc-nd/3.0/us/
- Resource Type:
- Programs
- Title:
- Chicago Area Medical Archivists Medical History Symposium (2017), Edith Ayres and Helen Burnett Wood Memorial Symposium (The)
- Description:
- The Edith Ayres and Helen Burnett Wood Memorial Symposium, jointly sponsored by Midwest Nursing History Research Center, College of Nursing, UIC, and the Chicago Area Medical Archivists, was held April 20, 2017 at University of Illinois College of Nursing, 3rd Floor Event Center, Chicago, IL. (This jointly sponsored event in 2017 occurred in lieu of the traditional (fall) CAMA medical history symposium.)
- Keyword:
- CAMA, Midwest Nursing History Research Center, Program, Symposium
- Subject: MESH:
- Libraries, Medical, Archives, History of Medicine, History of Nursing
- Subject: LCSH:
- Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Chicago Area Medical Archivists, Midwest Nursing History Research Center
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2017-04-17
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Programs
- Title:
- Chicago Area Medical Archivists Medical History Symposium (2021)
- Description:
- Program of the CAMA Medical History Symposium held virtually on September 30, 2021.
- Keyword:
- CAMA, Program, Symposium
- Subject: MESH:
- Libraries, Medical, Archives, History of Medicine
- Subject: LCSH:
- Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Chicago Area Medical Archivists
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2021-09-30
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Programs
- Title:
- Chicago Area Medical Archivists Medical History Symposium (2020)
- Description:
- Program of the CAMA Medical History Symposium held virtually on September 18, 2020.
- Keyword:
- CAMA, Program, Symposium
- Subject: MESH:
- Libraries, Medical, Archives, History of Medicine
- Subject: LCSH:
- Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Chicago Area Medical Archivists
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2020-09-18
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Programs
- Title:
- Chicago Area Medical Archivists Medical History Symposium (2019)
- Description:
- Program of the CAMA Medical History Symposium hosted by and held September 20, 2019 in the Level 2 conference room at Galter Health Sciences Library & Learning Center, Northwestern University Feinberg School of Medicine, Chicago, IL.
- Keyword:
- CAMA, Program, Symposium
- Subject: MESH:
- Libraries, Medical, Archives, History of Medicine
- Subject: LCSH:
- Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Chicago Area Medical Archivists
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2019-09-20
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Programs
- Title:
- Chicago Area Medical Archivists Medical History Symposium (2018)
- Description:
- Program of the CAMA Medical History Symposium [entitled "Fall History Symposium" in the program] held October 11, 2018 in Classroom J (2nd Floor), Prentice Women's Hospital, Chicago, IL.
- Keyword:
- CAMA, Program, Symposium
- Subject: MESH:
- Libraries, Medical, Archives, History of Medicine
- Subject: LCSH:
- Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Chicago Area Medical Archivists
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2018-10-11
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Programs
- Title:
- Chicago Area Medical Archivists Medical History Symposium (2016)
- Description:
- Program of the CAMA Medical History Symposium [listed as "Meeting & Presentations" in program], held December 7, 2016 in the Special Collections and Archives Room, at the Library of the Health Sciences, University of Illinois at Chicago, Chicago, IL.
- Keyword:
- CAMA, Program, Symposium
- Subject: MESH:
- Libraries, Medical, Archives, History of Medicine
- Subject: LCSH:
- Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Chicago Area Medial Archivists
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2016-12-07
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Programs
- Title:
- Chicago Area Medical Archivists Medical History Symposium (2013)
- Description:
- Program of the annual CAMA Medical History Symposium held October 31, 2013 in the Board of Regents Room, American College of Surgeons, Chicago, IL
- Keyword:
- CAMA, Program, Symposium
- Subject: MESH:
- Libraries, Medical, Archives, History of Medicine
- Subject: LCSH:
- Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Chicago Area Medical Archivists
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2013-10-31
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Programs
- Title:
- Chicago Area Medical Archivists Medical History Symposium (2012)
- Description:
- Program of the 10th annual CAMA Medical History Symposium held October 26, 2012 in the 16th Floor Conference Room at Lurie Childrens Hospital, Chicago, IL
- Keyword:
- CAMA, Program, Symposium
- Subject: MESH:
- Libraries, Medical, Archives, History of Medicine
- Subject: LCSH:
- Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Chicago Area Medical Archivists
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2012-10-26
- Rights:
- http://creativecommons.org/licenses/by-nc-nd/3.0/us/
- Resource Type:
- Programs
- Title:
- Chicago Area Medical Archivists Medical History Symposium (2011)
- Description:
- Program of the 9th annual CAMA Medical History Symposium held October 28, 2011 at Wood Library-Museum of Anesthesiology, American Society of Anesthesiologists, Park Ridge, IL
- Keyword:
- CAMA, Program, Symposium
- Subject: MESH:
- Libraries, Medical, Archives, History of Medicine
- Subject: LCSH:
- Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Chicago Area Medical Archivists
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Park Ridge, Illinois, United States
- Language:
- English
- Date Created:
- 2011-10-28
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Programs
- Title:
- Chicago Area Medical Archivists Medical History Symposium (2010)
- Description:
- Program of the CAMA Medical History Symposium held October 27, 2010 at Pritzker Auditorium, Northwestern Memorial Hospital, Chicago, IL.
- Keyword:
- CAMA, Program, Symposium
- Subject: MESH:
- Libraries, Medical, Archives, History of Medicine
- Subject: LCSH:
- Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Chicago Area Medical Archivists
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2010-10-27
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Programs
- Title:
- Chicago Area Medical Archivists Medical History Symposium (2008)
- Description:
- Program of the 7th annual CAMA Medical History Symposium held October 24, 2008 at the Library of the Health Sciences, Special Collections Department, University of Illinois at Chicago, Chicago, IL.
- Keyword:
- CAMA, Program, Symposium
- Subject: MESH:
- Libraries, Medical, Archives, History of Medicine
- Subject: LCSH:
- Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Chicago Area Medical Archivists
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2008-10-24
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Programs
- Title:
- Chicago Area Medical Archivists Medical History Symposium (2007)
- Description:
- Program of the CAMA [Medical] History Symposium held October 26, 2007 at Galter Health Sciences Library [Northwestern University], Chicago, IL.
- Keyword:
- CAMA, Program, Symposium
- Subject: MESH:
- Libraries, Medical, Archives, History of Medicine
- Subject: LCSH:
- Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Chicago Area Medical Archivists
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2007-10-26
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Programs
- Title:
- Chicago Area Medical Archivists Medical History Symposium (2005)
- Description:
- Program of the 4th annual CAMA Medical History Symposium held October 21, 2005 at the American Academy of Pediatrics building, Elk Grove Village, IL.
- Keyword:
- CAMA, Symposium, Program
- Subject: MESH:
- Libraries, Medical, Archives, History of Medicine
- Subject: LCSH:
- Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Chicago Area Medical Archivists
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Elk Grove Village, Illinois, United States
- Language:
- English
- Date Created:
- 2005-10-21
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Programs
- Title:
- Chicago Area Medical Archivists Medical History Symposium (2003)
- Description:
- Program of the 2nd annual CAMA Medical History Symposium held October 16, 2003 at the American Society for Clinical Pathology building, Chicago, IL.
- Keyword:
- CAMA, Program, Symposium
- Subject: MESH:
- Libraries, Medical, Archives, History of Medicine
- Subject: LCSH:
- Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Chicago Area Medical Archivists
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2003-10-16
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Programs
- Title:
- Chicago Area Medical Archivists Medical History Symposium- Programs
- Description:
- Programs of medical history symposia organized, sponsored, and hosted by members of Chicago Area Medical Archivists (CAMA). Symposia were first held in 2002 and were not held 2009, 2014, 2015. / The Chicago Area Medical Archivists (CAMA) is an informal group of archivists, librarians, healthcare professionals, and others interested in medical history in the Chicago area.
- Keyword:
- CAMA
- Subject: MESH:
- Chicago, Archives, Libraries, Medical, History of Nursing, History of Medicine
- Subject: LCSH:
- Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Chicago Area Medical Archivists (CAMA)
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Title:
- Institutional Repositories in the Health Sciences: A View of the Landscape
- Description:
- Brief introduction leading into a continuing education event entitled: CE 2: Panel discussion- Institutional Repositories- the joys and challenges, presented during the 2022 virtual Health Science Librarians of Illinois conference, September 8, 2022. The panel presenting use cases consisted of: Amanda Avery (Parkland College), Jennifer Deal (Advocate Aurora Health), Sandra De Groote (University of Illinois-Chicago), and Mingyan Li (University of Illinois-Chicago).
- Keyword:
- institutional repository, Health Science Librarians of Illinois, HSLI, CE
- Subject: MESH:
- Libraries, Medical, Libraries, Hospital
- Subject: LCSH:
- Institutional repositories, Medical libraries, Continuing education
- Subject: Geographic Name:
- Illinois
- Creator:
- Kubilius, Ramune K., Palmer, Lisa A.
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Location:
- Illinois, Illinois, United States
- Language:
- English
- Date Created:
- 2022-08
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Presentation
- Title:
- Getting to Know the NIH Policy on Data Management and Sharing
- Description:
- PowerPoint presentation created for a Galter Health Sciences Library & Learning Center class outlining recommendations for compliance with the 2023 NIH Policy for Data Management and Sharing.
- Keyword:
- research data management, data sharing, data repositories, NIH Policy for Data Management and Sharing
- Subject: MESH:
- Data Management
- Subject: LCSH:
- Institutional repositories
- Creator:
- Gonzales, Sara
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-08-22
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Presentation
- Title:
- Assessments for Identifying Tactile Deficits in Individuals with Stroke: A Scoping Review
- Description:
- A protocol describing a scoping review to summarize tactile assessments for individuals with stroke at their upper extremities.
- Abstract:
- Accurate perception of objects that one interacts with, through touch, is instrumental to successfully learn and perform physical activities. Studies indicate that the perception of touch, or tactile stimuli, in the upper extremities is commonly negatively impacted after a stroke. In this scoping review, we seek to examine existing tactile assessments for the upper extremity of individuals with stroke. We aim to determine whether there is a gap in existing approaches that limits our understanding of the source of tactile perceptual deficits post-stroke. This information will be beneficial to understand the clinical value of existing assessments and potentially spur the development of new targeted assessments.
- Keyword:
- Tactile Assessment
- Subject: MESH:
- Stroke, Touch Perception, Patient Outcome Assessment
- Creator:
- Nayak, Karan Siddarth, Sydnor, Lindsey, Wafford, Q. Eileen, Sullivan, Jane, Parcetich, Kevin, Miner, Daniel, Paul, Arco, Gurari, Netta
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-08-12
- Rights:
- http://creativecommons.org/licenses/by/3.0/us/
- Resource Type:
- Study Design
- Title:
- Food Insecurity among Asian Americans: A Scoping Review Protocol
- Keyword:
- Food Insecurity, Asian American
- Subject: MESH:
- Food Insecurity, Asian
- Subject: Geographic Name:
- United States
- Creator:
- Ro, Suji
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Rights:
- All rights reserved
- Resource Type:
- Study Design
- Title:
- Inter-ICU Transfer of Patients with Acute Respiratory Failure-A Scoping Review
- Abstract:
- Rationale:Inter-ICU transfer of critically ill Acute Respiratory Failure Patients (ARF) are increasingly common in the current landscape of critical care delivery, especially highlighted during the COVID-19 pandemic. A major driver for inter-ICU transfer of ARF patients is the increasing evidence base that suggests that mortality and morbidity are reduced by receiving care at high-resource hospitals. However, no uniform guidance exists to help clinicians decide who, why, when, or where ICU patients with ARF should be transferred. Unfortunately, due to the lack of current guidance, each interface has opportunities for both implicit and explicit bias to influence decision-making and care. We conduct this scoping review to ask these questions that have been un answered in a comprehensive review the what, who, why, when and where of ARF patient transfers between intensive care units.
- Keyword:
- transfer patients, intensive care units
- Subject: MESH:
- Patient Transfer, Intensive Care Units, Respiratory Insufficiency
- Subject: Geographic Name:
- United States
- Creator:
- Ludwig, Amy, Nadig, Nandita R, Slota, Jennifer Maling, Johnson, Julie
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-10
- Rights:
- http://creativecommons.org/publicdomain/zero/1.0/
- Resource Type:
- Review
49. Impact of easily accessible health information on decision-making as it regards COVID-19 vaccination
- Title:
- Impact of easily accessible health information on decision-making as it regards COVID-19 vaccination
- Keyword:
- pandemic, COVID-19, vaccination, patient education material
- Subject: MESH:
- COVID-19 Vaccines, Patient Education as Topic, Pandemics, Health Literacy
- Creator:
- Ukeje, Chideraa
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-05-12
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Masters Thesis
- Title:
- Risk of Heart Failure Among Breast Cancer Survivors
- Abstract:
- Background: Cardiovascular disease (CVD) is prevalent among breast cancer survivors, leading to an increased risk of death in this patient population. Shared modifiable risk factors between CVD and cancer, such as obesity, physical inactivity, and diet, could offer a potential explanation for the increasing prevalence of CVD among cancer survivors. Another possible explanation is that frequently used breast cancer therapies, such as trastuzumab, are associated with cardiotoxicity, which could increase the risk of developing heart failure. Objective: The primary objective of this study was to assess if the age at breast cancer diagnosis was associated with the risk of heart failure across various age groups. Another objective of the study was to examine if the risk of heart failure among breast cancer survivors differed by chemotherapy use, specifically trastuzumab. Methods: A retrospective cohort analysis was conducted using 22,205 adult female breast cancer patients treated at the Northwestern Memorial Hospital. Patients were grouped into 50 years, 51-64 years, and 65 years for the age at breast cancer diagnosis. Kaplan-Meier curves for time to heart failure diagnoses were generated for the various age at diagnosis groups, and the Cox Proportional Hazards assumption was evaluated. Multivariable Cox proportional hazards regression models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) with adjustment for important covariates concerning demographics, cancer characteristics, lab values, and comorbidities. Results: In assessing heart failure for all female breast cancer patients, older age at breast cancer diagnosis was associated with an increased risk of heart failure (HR 2.23, 95% CI 1.70-2.91 and HR 6.61, 95% CI 5.16-8.47 for 51-64 years and 65 years compared to 50 years, respectively). When adjusted for race, ethnicity, second cancer, smoking status, baseline cholesterol, baseline HDL, baseline glucose, coronary artery disease, and myocardial infarction, older age at breast cancer diagnosis remained associated with an increased risk of heart failure (HR 2.14, 95% CI 1.50-3.04 and HR 5.33, 95% CI 3.83-7.41 for 51-64 years and 65 years compared to 50 years, respectively). In assessing heart failure among female breast cancer patients treated with trastuzumab, age at breast cancer diagnosis was associated with an increased risk of heart failure only in the 65 years group (HR 1.90, 95% CI 0.84-4.29 and HR 3.29, 95% CI 1.43-7.58 for 51-64 years and 65 years compared to 50 years, respectively). When adjusted for race, ethnicity, and second cancer, age at breast cancer diagnosis was associated with an increased risk of heart failure in all age groups (HR 2.71, 95% CI 1.09-6.73 and HR 4.82, 95% CI 1.88-12.33 for 51-64 years and 65 years compared to 50 years, respectively) in female breast cancer patients treated with trastuzumab. Discussion: This analysis suggested a strong association between the age at breast cancer diagnosis and the risk of heart failure when examining all female breast cancer patients. Individuals diagnosed with breast cancer at an older age were at an increased risk of developing heart failure. However, this association varied when evaluating only female breast cancer patients treated with trastuzumab. This study provides important foundations to assessing the long-term impacts of breast cancer diagnosis and treatments, especially among younger adults compared to healthy peers. Thus, additional large-scale studies conducting a case-control analysis in this population and longitudinal studies in additional populations are required to fully elucidate the effect of age at breast cancer diagnosis on the risk of heart failure.
- Keyword:
- cardiovascular disease, breast cancer, survivors, risk factors, heart failure
- Subject: MESH:
- Heart Failure, Breast Neoplasms, Heart Disease Risk Factors, Cardiovascular Diseases
- Subject: Geographic Name:
- Illinois--Chicago
- Subject: Name:
- Northwestern Memorial Hospital
- Creator:
- Singam, Manisha
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-05-22
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Masters Thesis
51. Analysis of National Alliance on Mental Illness (NAMI) Chicago HelpLine Referral Data (2019-2020)
- Title:
- Analysis of National Alliance on Mental Illness (NAMI) Chicago HelpLine Referral Data (2019-2020)
- Abstract:
- Purpose: NAMI Chicago has a HelpLine for those who wish to contact them with mental health & wellness needs.1 There is a lot of data that is logged regarding these calls, and a lot of it is being analyzed already; however, there is an area in which analysis is definitely still needed, specifically with respect to resource connections, i.e., referrals. In other words, data pertains to what happens after a caller interfaces with the NAMI Chicago HelpLine & is directed toward a resource. In some cases, there are specific follow-ups by NAMI Chicago that happen. The objective is to provide quality assurance program evaluation and feedback to NAMI Chicago about using de-identified call data to analyze their processes: potential areas at the outset included barriers to referrals, facilitators, areas for improvement, etc. Procedures: The purpose of this research is quality assurance around barriers to follow-up identified by NAMI Chicago call center responders and to assess the frequency of the most typical barriers. NAMI Chicago provides telephone referrals to callers seeking mental health services throughout the Chicago area. It was estimated that 13,000 calls were fielded by NAMI in 2020 and an analysis of the barriers experienced by callers seeking referrals to mental health services will help NAMI improve services to people in the community. This analysis has ended up examining calls placed across all of 2019, as well as all of 2020.
- Keyword:
- mental health, health call center, Chicago, mental health services, telehealth
- Subject: MESH:
- Mental Health Services, Call Centers, Telemedicine
- Subject: Geographic Name:
- Illinois--Chicago
- Creator:
- Rapoport, Andy
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-06-02
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Masters Thesis
- Title:
- An Assessment of Multisectoral Factors Influencing Global Trends in Neonatal Mortality Rates
- Abstract:
- Objective: Neonatal mortality continues to be a global burden on healthcare. Multisectoral factors have been identified that are associated with neonatal mortality rate. The primary objective of this study was to determine the extent of the association between these variables and neonatal mortality rate, and which variables are key in targeting for future public health policy to reduce neonatal death. Methods: Preliminary data analysis revealed variables believed to be associated with neonatal mortality rate. The twenty countries that account for 75% of total global neonatal death were identified. STATA statistical analysis software was used to conduct data analysis from 2000 to 2019, in 5-year intervals, for all countries. Regression analyses and correlation matrices were run for neonatal mortality and variables such as median income, stillbirth rates, healthcare spending, low birth weight, relative number of physicians, relative number of nurses, literacy level, and maternal mortality ratio. The variables were entered into a series of models that accounted for different combinations. Model A included neonatal mortality rate, maternal mortality ratio change, and median income change. Model B included low birth weight instead of maternal mortality ratio. Model C included neonatal mortality rate, low birth weight rate, and healthcare spending. Model D included neonatal mortality rate, median income, and literacy level. Results: The mean change in nation-level median income over the last 20 years was found to be 1.63 times the median income in 2000-2004. The regression analysis revealed that an increase in median income was associated with a decrease in neonatal mortality rate. There was a 2.7-unit change in neonatal mortality rate seen for every 1-unit change in low-birth-weight rate, a 0.24 unit decrease for every 1-unit change in literacy level, a 1.47-point decrease for every 1-unit change of healthcare spending, and a 0.02-unit change for every 1-unit change in maternal mortality ratio from 2000-2004 through 2015-2019. Model A demonstrated that there was a 0.02 change in neonatal mortality rate for every 1-unit change in maternal mortality ratio, and a -1.58-unit change for every 1 unit of median income. Model B demonstrated that there was a 2.39-unit change in neonatal mortality rate for every 1-unit change in low-birth-weight rate, and a -1.46-unit change for every 1 unit of median income. Model C demonstrated that there was a 2.56-unit change in neonatal mortality rate for every 1-unit change in low-birth-weight rate, and a -1.32-unit change for every 1 unit of healthcare spending. Model D demonstrated that there was a -0.23-unit change in neonatal mortality rate for every 1 unit increase in literacy level, and a -1.45-unit change for every 1 unit increase in median income. Discussion: The results of this analysis suggest the highest degree of correlation between neonatal mortality rate, maternal mortality ratio, and median income. There results offer foundational starting points for research in neonatal mortality and associated multisectoral factors. Further research is necessary to determine how these results can be used to target mortality reduction in the twenty countries determined to have the highest neonatal total deaths. Focusing on median income as a strongly correlated factor of neonatal mortality rate may allow for the future creation of targeted public health policies. Creating models that account for a higher percentage of the variance would be useful as well. Future analysis should focus on deriving deeper associations between the variables through further literature review or data collection. In addition, future research should focus on determining why the association between maternal mortality ratio and neonatal mortality rate wasnt as high as anticipated. Eventually, these findings could be used to influence public health programs, policy, or planning by aiding in the creation of a dissemination plan for a best practice training program aimed at reducing neonatal mortality rated globally.
- Keyword:
- neonatal mortality, income, health risks, public health
- Subject: MESH:
- Infant Mortality, Income, Risk Factors, Public Health
- Creator:
- Karmazin, Michelle
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-05-25
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Masters Thesis
- Title:
- Understanding Racial Disparities in Low Birth Weight
- Abstract:
- This paper summarizes the research on the epidemiology of low birth weight (LBW) births focusing on the evidence about disparities in low birth weight for Black infants in the US. Studies have continually shown that Black mothers and their infants are at higher risk for pregnancy-related complications such as LBW. LBW, a leading cause of infant death for this racial group, is associated with a multitude of risk factors, with the major two dimensions being health status and health care. Evidence suggests that the accumulation of chronic stress over a lifetime culminates in health problems for Black women, thus leading to the conditions for LBW to occur. There is growing acceptance of the context of societal and systemic racism that creates a toxic and harmful environment for Black mothers and how this results in physiological stress that directly causes infant and maternal mortality. Although racial disparities in low birth weight are widely known in the medical community, prevention requires addressing the harmful social conditions that underlie these inequitable outcomes. This paper focuses on the way in which Black women and infants are disproportionately burdened with the effects of LBW. It concludes by discussing how changes can, with careful consideration and implementation, drive efforts to protect the Black infants and mothers as part of a holistic, patient-centered approach.
- Keyword:
- low birth weight, Black infants, racial disparities, physiological stress
- Subject: MESH:
- Infant, Low Birth Weight, Black People, Health Disparate, Minority and Vulnerable Populations, Psychological Distress
- Subject: Geographic Name:
- United States
- Creator:
- Jones, Kiana A.
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-05-17
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Masters Thesis
- Title:
- Understand success and challenges in adaptation and implementation of Quality Improvement Collaboratives to help End the HIV Epidemic in Namibia and Zimbabwe
- Abstract:
- Background: Improving HIV health care quality remains an unfulfilled goal necessary to both reduce mortality for people living with HIV and reach epidemic control. Although a common strategy, improvement collaboratives (ICs) are variably effective in improving quality and better understanding of their implementation and adaptation to local contexts is needed. We applied implementation science methods to study how Ministry of health-led ICs supported by UCSF-HEALTHQUAL were implemented in Namibia and Zimbabwe to support and accelerate improvement in the HIV care cascade including rapid uptake of ART and viral load suppression. Methods: We applied two implementation research frameworks, EPIS [Exploration, Preparation, Implementation, and Sustainment] and CFIR [Consolidated Framework for Implementation Research] to guide data collection and analysis for a retrospective mixed methods case study of the ICs. We conducted nine key informant interviews, field observations, and document review to identified implementation strategies contextual factors and implementation outcomes. Results were synthesized using content analysis and organized by EPIS stage. Results: Many implementation strategies for both countries were similar across the exploration, preparation and implementation stages, including alignment with national priorities and guidelines, leveraging existing relationships with stakeholders, QI capacity-building, and adaptations of IC components and data collection tools. Important contextual factors of both ICs were: national leadership, donor funding and country resources, baseline national and local QI knowledge, capacity and culture, existing implementation partnerships, data system integrity, and geography. All sites in both countries completed QI projects. Active peer-to-peer learning occurred; and improvement was demonstrated in many of the targeted measures. Implementation challenges encountered included data validity and quality, finite resources and staff turnover. Limited information was available for sustainment improvement, but both countries have scaled ICs, indicating longer term capacity in QI. Conclusions: Successful implementation of ICs involved adaptation to local context and other strategies which leveraged facilitating factors and addressed barriers with strong adoption and fidelity. Other key lessons included early stakeholder engagement, national leadership engagement, alignment with national priorities, and attention to developing QI capacity. These results can inform future efforts to accelerate improvement of HIV care and treatment through ICs in the region and improving quality more broadly.
- Keyword:
- HIV, health care quality, improvement collaboratives, Namibia, Zimbabwe, epidemic
- Subject: MESH:
- HIV, Quality of Health Care, Intersectoral Collaboration, Epidemics
- Subject: Geographic Name:
- Namibia, Zimbabwe
- Creator:
- Jok, Christie, Hirschhorn, Lisa Ruth, Persaud, Udita, Agins, Bruce, Murungu, Joseph, Basenero, Apollo, Neidel, Julie, Khabo, Bobbie, Mabuko, Japhet, Ikeda, Dan, Schaefer, Willemijn
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-05-24
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Masters Thesis
- Title:
- Using Natural Language Processing to Identify and Classify Incidental Findings
- Abstract:
- Over the last few years there has been an explosion of deep learning research leading to quick development of very powerful algorithms that have found their way into every industry. There are a few major reasons why deep learning is particularly attractive for algorithm development. The algorithms can complete complex tasks with surprisingly high accuracy. Deep learning models, unlike machine learning models, automatically extract features that are important for the algorithms task. The deep learning community has established and open-sourced high quality feature extractors and classifier architectures with weights included for most data domains. Lung cancer is a major cause of morbidity and mortality in the US and globally. Lung cancers are conditions that include a silent phase during which intervention is highly effective, but patients are asymptomatic so there is no indication for an exam. It is common that patients with symptoms unrelated to a forming cancer get imaging to work-up their current illness. During these times an incidental nodule in the lungs may be captured and a radiologist may recommend a follow-up, but there are few mechanisms in place to ensure that these patients have their follow-up completed. As a point of quality control, NM would like to maximize the likelihood that a patient with an incidentally noted lung nodule with follow-up recommendations will receive appropriate follow-up. In order to meet this goal, we have developed an EHR ready artificial intelligence pipeline that identifies reports containing text suggesting a lung nodule requiring follow-up. We find that upon retrospective review, we are able to use machine learning to capture reports containing lung nodules requiring follow-up with a sensitivity of 87% and specificity of 87%.
- Keyword:
- deep learning, algorithms, lung cancer, lung nodule
- Subject: MESH:
- Deep Learning, Algorithms, Lung Neoplasms
- Creator:
- Galal, Galal
- Contributor:
- Huang, Jonathan, Mukhin, Vladislav, Soni, Priyanka, Byrd, Thomas, Etemadi, Mozziyar
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-04-16
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Masters Thesis
- Title:
- Identifying Predictors of Long Length of Stay and Mortality for General Surgery Patients in Surgical Intensive Care Units: A Comparative Study
- Abstract:
- Objective: Approximately 5 million patients are admitted to intensive care units (ICUs) annually in the United States, with 500,000 of these patients dying per year during their admission. We aim to provide unadjusted rates of complications and mortality in a cohort of surgical ICU patients and to compare outcomes between a large, urban, academic referral center and community hospitals using a risk-adjusted model. Methods: We constructed a retrospective cohort of patients who underwent general surgery procedures and stayed in the surgical ICUs at Northwestern Memorial Hospital (NMH), Central DuPage Hospital (CDH), and Lake Forest Hospital (LFH) from March 2018-April 2021. Patients at the latter suburban community hospital sites were grouped. Patients treated at NMH versus CDH and LFH were compared using univariate analyses of complications and mortality and multivariable analyses adjusted for patient clinical and sociodemographic characteristics. Results: Univariate analysis demonstrated that an ICU stay at NMH was associated with higher rates of hyperglycemia (45.8% vs. 30.7%, p <0.001), malnutrition (33.3% vs. 20.5%, p<0.001), and wound infections (8.9% vs 4.9%, p = 0.03), but lower mortality rates (4.7% vs 8.8%, p = 0.006). BMI, ASA score, surgery type, and having subsequent procedures were the characteristics most commonly associated with adverse events. Multivariate analysis demonstrated that hospital site was not significantly associated with long length of stay (OR = 1.1 [0.60-2.03]) but being treated at CDH/LFH was associated with higher mortality (OR = 2.34 [1.16-4.73]). Discussion: These data provide baseline rates of adverse outcomes in a large cohort of surgical ICU patients, and show that mortality, but not length of stay, may differ between the surgical ICUs studied. Our results provide a foundation for future study of surgical ICU outcomes within the Northwestern Healthcare network and may be hypothesis-generating for additional research within this population.
- Keyword:
- intensive care unit, hospital, mortality
- Subject: MESH:
- Hospital Mortality, Intensive Care Units, Surgical Procedures, Operative, Length of Stay
- Subject: Geographic Name:
- Illinois--Northern
- Creator:
- Bushara, Omar
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-05-11
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Masters Thesis
- Title:
- The Association Between Timely Access to Pediatric Appendicitis Care and Neighborhood Factors
- Abstract:
- BACKGROUND: Appendicitis is the most common acute pediatric surgical condition, with 30% of patients presenting as complicated. Complicated appendicitis may indicate a delay in seeking care, resulting in higher complication rates, longer lengths of stay and higher readmission rates compared to simple appendicitis and can serve as indicator for access to care. Although patient-level and neighborhood-level factors can affect timely access to care, the effect of neighborhood factors on access to pediatric surgical care remains poorly understood. We examined the association between neighborhood social determinants of health and the odds of presenting with complicated appendicitis and unplanned post-discharge healthcare utilization. METHODS: A retrospective, cohort study of pediatric patients with appendicitis between 2016-2018 were identified using the Pediatric Health Information System (PHIS) database. Neighborhood characteristics were captured using the Child Opportunity Index (COI), a validated, comprehensive measure of 29 neighborhood characteristics known to impact childrens health. Nationally-normalized COI measurements were divided into quintiles from very low to very high opportunity. Hierarchical logistic regression was used to model the odds of presenting with complicated appendicitis as a function of COI. Adjustments included age, sex, race/ethnicity and insurance. A similar model was assessed for unplanned healthcare utilization, including emergency department visits and readmissions. RESULTS: A total of 67,489 patients had appendicitis with 21,728 (32.2%) being complicated. Patients were 43.3% non-Hispanic white, 60.1% male, 47.8% publicly-insured, and predominantly aged 10-14 years (42.7%). Patients living in very low COI neighborhoods were 34% more likely to present with complicated appendicitis (OR 1.34, 95%CI 1.26, 1.42) compared to those in very high COI neighborhoods. There was no significant association between COI level and unplanned post-discharge healthcare utilization. CONCLUSIONS: Children living in lower COI neighborhoods had an increased risk of presenting with complicated appendicitis; however, neighborhood characteristics were not associated with unplanned healthcare utilization post-discharge. Given increased interest among health systems, public health organizations and third-party payers in mitigating the effects of disadvantaged neighborhood characteristics on health outcomes, these findings may inform policies and programs that seek to improve equitable outcomes in pediatric surgical care.
- Keyword:
- Social Determinants of Health, pediatric surgery, appendicitis, neighborhood
- Subject: MESH:
- Pediatrics, Appendicitis, Social Determinants of Health, Neighborhood Characteristics
- Creator:
- Bouchard, Megan E, Kan, Kristin, Tian, Yao, Casale, Mia, Smith, Tracie, DeBoer, Christopher, Linton, Samuel C, Abdullah, Fizan, Ghomrawi, Hassan
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-03-04
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Masters Thesis
- Title:
- Identifying mobile health technology experiences and preferences of low-income pregnant women with diabetes
- Abstract:
- BACKGROUND: Rapid expansion of mobile technology has resulted in the development of many mobile health ("mHealth") platforms for health monitoring and support. However, applicability, desirability, and tailoring of these platforms for pregnant women, particularly in populations who experience the greatest health inequitiessuch as women with diabetes mellitus (DM) and/or those with greater socioeconomic barriersremains unknown. The objective is to understand low-income pregnant women's experiences and preferences for mHealth tools to support pregnancy and improve DM self-management. METHODS: Low-income pregnant and postpartum women were included in individual interviews or focus groups; women with and without type 2 or gestational DM were included. Analysis was performed with the constant comparison method. RESULTS: In this population of 45 (N=37 with DM) low-income, largely minority, pregnant and postpartum women, 100% reported access to smartphones and prior experience with apps. Interest in mHealth to support health and engagement during pregnancy was high. Preferences for general mHealth features included education that reduces uncertainty, support communities, visualizing progress, convenient access to information, and support for better management of pregnancy-related tasks. Preferred design elements included personalization, interactive features, and integrated graphics. Women with DM expressed multiple additional DM-specific needs, including support tools for DM self-management and self-regulation tasks.
- Keyword:
- behavioral intervention, diabetes, mobile health, pregnancy, smartphone
- Subject: MESH:
- Diabetes Mellitus, Psychosocial Intervention, Pregnancy, Smartphone, Telemedicine
- Creator:
- Birch, Eleanor, Leziak, Karolina, Jackson, Jenise, Strohbach, Angelina, Niznik, Charlotte, Yee, Lynn M
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-04-12
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Masters Thesis
- Title:
- Sustainable Agriculture and Natural Resource Management in Sub-Saharan Africa for Climate Change Resilience
- Abstract:
- Climate change repercussions in Sub-Saharan Africa are permeating both natural and human systems in numerous ways. This paper therefore seeks to identify (1) sustainable agricultural policies and (2) natural resource management policies that would improve climate change resilience in Sub-Saharan Africa. It adopts a multi-goal policy analysis approach. The literature review on policy formulation and implementation revealed several themes, such as complex relationships between actors, disjointed policy implementations, and a one-size-fits-all approach. Furthermore, the policy analysis reveals that national policy for alternative agriculture, green economy, and agricultural and environmental schemes have different predicted outcomes in their implementations as climate change resilience strategies in Sub-Saharan Africa. Concerning agricultural policies that would enhance climate change resilience in Sub-Saharan Africa, alternative agricultural practices include dependence on recycled and green practices, animal manure, and localized and friendly land tillage. The green economy entails layered agricultural systems and the cultivation of local plants, while agri-environmental schemes encompass practices such as organic farming and crop rotation. This paper recommends a combination of national policies for alternative agriculture, the green economy, and agri-environmental schemes to build climate change resilience in agriculture and natural resource management in Sub-Saharan Africa.
- Keyword:
- climate change, sustainability, agriculture, natural resources, Sub-Saharan Africa, national policy
- Subject: MESH:
- Climate Change, Natural Resources, Environmental Policy
- Subject: LCSH:
- Sustainable agriculture
- Subject: Geographic Name:
- Africa, Sub-Saharan
- Creator:
- Berbos, Emma
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2021-04-29
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Masters Thesis
- Title:
- 2021-2022 Series 09 NUCATS Articulating your Mentoring Philosophy and Plan
- Description:
- Presentation discusses the different between a mentoring plan and mentoring philosophy, the "how's" and "why's" of mentoring, and creating a mentoring philosophy that is unique to you. This presentation was highly interactive leaving time for participants to reflect and write on their own throughout.
- Keyword:
- NUCATS, Mentoring, Mentoring Philosophy, Mentoring Plan
- Subject: MESH:
- Mentoring
- Creator:
- Goodman, Adam
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-06-09
- Rights:
- http://creativecommons.org/licenses/by-nc/3.0/us/
- Resource Type:
- Presentation
- Title:
- Quality Improvement for the Global Health Trainee
- Keyword:
- quality improvement , global health education
- Subject: MESH:
- Global Health, Quality of Health Care
- Creator:
- Visek, Caitlin Anne
- Contributor:
- Doobay-Persaud, Ashti
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Other
- Title:
- Global Health Quality Improvement Educational Resources
- Keyword:
- quality improvement , global health education
- Subject: MESH:
- Global Health, Quality of Health Care, Education, Distance
- Creator:
- Visek, Caitlin Anne
- Contributor:
- Doobay-Persaud, Ashti
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Other
- Title:
- Maturity Model Overview for AMIA Summit 2022
- Keyword:
- Maturity, Maturity models
- Subject: MESH:
- Strategic Planning
- Creator:
- Starren, Justin B
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-05-23
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Presentation
- Title:
- Local Informal Network Support and Shared Expertise: the 20-year experience of CAMA
- Description:
- Lightning talk presentation made during the virtual SLA Midwest Symposium on June 10, 2022 about CAMA (Chicago Area Medical Archivists), including milestones from its 20 year history. / Presentation also made on-site (with minor updates) during the Midwest/Medical Library Association meeting on October 24, 2022 under the alternate title: "20 Years of Local Informal Network Support and Shared Expertise: Chicago Area Medical Archivists (CAMA)".
- Abstract:
- The Illinois group, Chicago Area Medical Archivists (CAMA) is an informal group, based in the greater Chicagoland area, that was formed in 2002. As an informal network of colleagues, CAMA has provided support for both novice and experienced information professionals charged with organizing their institutions archives or answering internal and external medical history questions, often in addition to other duties. As an informal, open membership group of librarians, archivists, healthcare professionals, and others interested in Chicago area medical history, CAMA complements other professional membership organizations. Members work at various health and clinical specialty associations, academic medical centers, universities, hospitals, and are local historians as well as independent researchers. This presentation, updating and expanding on a poster first presented in 2019 at the Health Science Librarians of Illinois conference *, spotlighted some of the more measurable milestones of the group, such as its long-standing annual medical history symposia. Examples were shared of ways the loosely structured network has been able to persist and thrive over the years, in providing concrete information support and a venue for its members of varied backgrounds who have shared their skills, knowledge, and expertise. Participation of CAMA members in the Chicago Collections Consortium was also highlighted. Could CAMA be useful to special librarians and could its model work for other information groups? Perhaps this presentation will provide some ideas or inspiration.
- Keyword:
- networking, CAMA, Chicago Area Medical Archivists, Health sciences, SLA, Midwest Chapter/ Medical Library Association
- Subject: MESH:
- Libraries, Medical, History of Medicine, History of Nursing
- Subject: LCSH:
- Librarians, Archivists, Libraries, Archives
- Subject: Geographic Name:
- Illinois--Chicago Metropolitan Area
- Creator:
- Kubilius, Ramune K., Keller Young, Megan
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-05-19
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Presentation
- Title:
- SARS-CoV-2 Surveillance in the Middle East and North Africa: Longitudinal Trend Analysis
- Original Bibliographic Citation:
- Post L, Marogi E, Moss CB, Murphy RL, Ison MG, Achenbach CJ, Resnick D, Singh L, White J, Boctor MJ, Welch SB, Oehmke JF. SARS-CoV-2 Surveillance in the Middle East and North Africa: Longitudinal Trend Analysis. Journal of Medical Internet Research. 2021;23(1):11.
- Abstract:
- Background: The COVID-19 pandemic has disrupted the lives of millions and forced countries to devise public health policies to reduce the pace of transmission. In the Middle East and North Africa (MENA), falling oil prices, disparities in wealth and public health infrastructure, and large refugee populations have significantly increased the disease burden of COVID-19. In light of these exacerbating factors, public health surveillance is particularly necessary to help leaders understand and implement effective disease control policies to reduce SARS-CoV-2 persistence and transmission. Objective: The goal of this study is to provide advanced surveillance metrics, in combination with traditional surveillance, for COVID-19 transmission that account for weekly shifts in the pandemic speed, acceleration, jerk, and persistence to better understand a country's risk for explosive growth and to better inform those who are managing the pandemic. Existing surveillance coupled with our dynamic metrics of transmission will inform health policy to control the COVID-19 pandemic until an effective vaccine is developed. Methods: Using a longitudinal trend analysis study design, we extracted 30 days of COVID-19 data from public health registries. We used an empirical difference equation to measure the daily number of cases in MENA as a function of the prior number of cases, the level of testing, and weekly shift variables based on a dynamic panel data model that was estimated using the generalized method of moments approach by implementing the Arellano-Bond estimator in R. Results: The regression Wald statistic was significant (chi(2)(5)=859.5, P<.001). The Sargan test was not significant, failing to reject the validity of overidentifying restrictions (chi(2)(294)=16, P=.99). Countries with the highest cumulative caseload of the novel coronavirus include Iran, Iraq, Saudi Arabia, and Israel with 530,380, 426,634, 342,202, and 303,109 cases, respectively. Many of the smaller countries in MENA have higher infection rates than those countries with the highest caseloads. Oman has 33.3 new infections per 100,000 population while Bahrain has 12.1, Libya has 14, and Lebanon has 14.6 per 100,000 people. In order of largest to smallest number of cumulative deaths since January 2020, Iran, Iraq, Egypt, and Saudi Arabia have 30,375, 10,254, 6120, and 5185, respectively. Israel, Bahrain, Lebanon, and Oman had the highest rates of COVID-19 persistence, which is the number of new infections statistically related to new infections in the prior week. Bahrain had positive speed, acceleration, and jerk, signaling the potential for explosive growth. Conclusions: Static and dynamic public health surveillance metrics provide a more complete picture of pandemic progression across countries in MENA. Static measures capture data at a given point in time such as infection rates and death rates. By including speed, acceleration, jerk, and 7-day persistence, public health officials may design policies with an eye to the future. Iran, Iraq, Saudi Arabia, and Israel all demonstrated the highest rate of infections, acceleration, jerk, and 7-day persistence, prompting public health leaders to increase prevention efforts.
- Keyword:
- COVID-19, SARS-CoV-2 surveillance, wave two, second wave, global COVID-19 surveillance, MENA public health surveillance, MENA COVID-19, Middle East and North Africa surveillance metrics, dynamic panel data, MENA econometrics, MENA SARS-CoV-2, Middle East and North Africa COVID-19 surveillance system, MENA COVID-19 transmission speed, MENA COVID-19 transmission acceleration, COVID-19 transmission deceleration, COVID-19 transmission jerk, COVID-19 7-day lag, SARS-CoV-2, Arellano-Bond estimator, generalized method of moments, GMM, Bahrain, Iran, Iraq, Israel, Jordan, Kuwait, Lebanon, Oman, Qatar, Saudi Arabia, Syria, United Arab Emirates, Yemen, Algeria, Djibouti, Egypt, Libya, Morocco, Tunisia
- Subject: MESH:
- SARS-CoV-2, Disease Transmission, Infectious , Health Policy, COVID-19
- Subject: LCSH:
- COVID-19 (Disease), Communicable diseases--Transmission, Medical policy
- Subject: Geographic Name:
- Middle East, Africa, North
- Creator:
- Post, Lori Ann, Marogi, Emily Philip, Moss, Charles B., Murphy, Robert Leo, Ison, Michael G, Achenbach, Chad J, Resnick, Danielle, Singh, Lauren, White, Janine Inui, Boctor, Michael Jacob, Welch, Sarah, Oehmke, James Francis
- Publisher:
- JMIR PUBLICATIONS, INC
- Language:
- English
- Date Created:
- 2021-01-15
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 33302252
- Title:
- A SARS-CoV-2 Surveillance System in Sub-Saharan Africa: Modeling Study for Persistence and Transmission to Inform Policy
- Original Bibliographic Citation:
- Post LA, Argaw ST, Jones C, Moss CB, Resnick D, Singh LN, Murphy RL, Achenbach CJ, White J, Issa TZ, Boctor MJ, Oehmke JF. A SARS-CoV-2 Surveillance System in Sub-Saharan Africa: Modeling Study for Persistence and Transmission to Inform Policy. Journal of Medical Internet Research. 2020;22(11):18.
- Abstract:
- Background: Since the novel coronavirus emerged in late 2019, the scientific and public health community around the world have sought to better understand, surveil, treat, and prevent the disease, COVID-19. In sub-Saharan Africa (SSA), many countries responded aggressively and decisively with lockdown measures and border closures. Such actions may have helped prevent large outbreaks throughout much of the region, though there is substantial variation in caseloads and mortality between nations. Additionally, the health system infrastructure remains a concern throughout much of SSA, and the lockdown measures threaten to increase poverty and food insecurity for the subcontinent's poorest residents. The lack of sufficient testing, asymptomatic infections, and poor reporting practices in many countries limit our understanding of the virus's impact, creating a need for better and more accurate surveillance metrics that account for under-reporting and data contamination. Objective: The goal of this study is to improve infectious disease surveillance by complementing standardized metrics with new and decomposable surveillance metrics of COVID-19 that overcome data limitations and contamination inherent in public health surveillance systems. In addition to prevalence of observed daily and cumulative testing, testing positivity rates, morbidity, and mortality, we derived COVID-19 transmission in terms of speed, acceleration or deceleration, change in acceleration or deceleration (jerk), and 7-day transmission rate persistence, which explains where and how rapidly COVID-19 is transmitting and quantifies shifts in the rate of acceleration or deceleration to inform policies to mitigate and prevent COVID-19 and food insecurity in SSA. Methods: We extracted 60 days of COVID-19 data from public health registries and employed an empirical difference equation to measure daily case numbers in 47 sub-Saharan countries as a function of the prior number of cases, the level of testing, and weekly shift variables based on a dynamic panel model that was estimated using the generalized method of moments approach by implementing the Arellano-Bond estimator in R. Results: Kenya, Ghana, Nigeria, Ethiopia, and South Africa have the most observed cases of COVID-19, and the Seychelles, Eritrea, Mauritius, Comoros, and Burundi have the fewest. In contrast, the speed, acceleration, jerk, and 7-day persistence indicate rates of COVID-19 transmissions differ from observed cases. In September 2020, Cape Verde, Namibia, Eswatini, and South Africa had the highest speed of COVID-19 transmissions at 13.1, 7.1, 3.6, and 3 infections per 100,0000, respectively; Zimbabwe had an acceleration rate of transmission, while Zambia had the largest rate of deceleration this week compared to last week, referred to as ajerk. Finally, the 7-day persistence rate indicates the number of cases on September 15, 2020, which are a function of new infections from September 8, 2020, decreased in South Africa from 216.7 to 173.2 and Ethiopia from 136.7 to 106.3 per 100,000. The statistical approach was validated based on the regression results; they determined recent changes in the pattern of infection, and during the weeks of September 1-8 and September 9-15, there were substantial country differences in the evolution of the SSA pandemic. This change represents a decrease in the transmission model R value for that week and is consistent with a de-escalation in the pandemic for the sub-Saharan African continent in general. Conclusions: Standard surveillance metrics such as daily observed new COVID-19 cases or deaths are necessary but insufficient to mitigate and prevent COVID-19 transmission. Public health leaders also need to know where COVID-19 transmission rates are accelerating or decelerating, whether those rates increase or decrease over short time frames because the pandemic can quickly escalate, and how many cases today are a function of new infections 7 days ago. Even though SSA is home to some of the poorest countries in the world, development and population size are not necessarily predictive of COVID-19 transmission, meaning higher income countries like the United States can learn from African countries on how best to implement mitigation and prevention efforts.
- Keyword:
- global COVID-19 surveillance, African public health surveillance, sub-Saharan African COVID-19, African surveillance metrics, dynamic panel data, generalized method of the moments, African econometrics, African SARS-CoV-2, African COVID-19 surveillance system, African COVID-19 transmission speed, African COVID-19 transmission acceleration, COVID-19 transmission deceleration, COVID-19 transmission jerk, COVID-19 7-day persistence, Sao Tome and Principe, Senegal, Seychelles, Sierra Leone, Somalia, South Africa, South Sudan, Sudan, Suriname, Swaziland, Tanzania, Togo, Uganda, Zambia, Zimbabwe, Gambia, Ghana, Guinea, Guinea-Bissau, Kenya, Lesotho, Liberia, Madagascar, Malawi, Mali, Mauritania, Mauritius, Mozambique, Namibia, Niger, Nigeria, Rwanda, Angola, Benin, Botswana, Burkina Faso, Burundi, Cameroon, Central African Republic, Chad, Comoros, Congo, Cote d'Ivoire, Democratic Republic of Congo, Equatorial Guinea, Eritrea, Ethiopia, Gabon
- Subject: MESH:
- SARS-CoV-2, Public Health Surveillance, Disease Transmission, Infectious, COVID-19
- Subject: LCSH:
- COVID-19 (Disease), Public health surveillance, Virus diseases--Transmission
- Subject: Geographic Name:
- Africa, Sub-Saharan
- Creator:
- Post, Lori Ann, Argaw, Salem Tibebe, Jones, Cameron Spencer, Moss, Charles B., Resnick, Danielle, Singh, Lauren Nadya, Murphy, Robert Leo, Achenbach, Chad J, White, Janine Inui, Issa, Tariq Ziad, Boctor, Michael Jacob, Oehmke, James Francis
- Publisher:
- JMIR PUBLICATIONS, INC
- Language:
- English
- Date Created:
- 2020-11-19
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 33211026
- Title:
- SARS-CoV-2 Surveillance System in Canada: Longitudinal Trend Analysis
- Original Bibliographic Citation:
- Post L, Boctor MJ, Issa TZ, Moss CB, Murphy RL, Achenbach CJ, Ison MG, Resnick D, Singh L, White J, Welch SB, Oehmke JF. SARS-CoV-2 Surveillance System in Canada: Longitudinal Trend Analysis. Jmir Public Health and Surveillance. 2021;7(5):11.
- Abstract:
- Background: The COVID-19 global pandemic has disrupted structures and communities across the globe. Numerous regions of the world have had varying responses in their attempts to contain the spread of the virus. Factors such as public health policies, governance, and sociopolitical climate have led to differential levels of success at controlling the spread of SARS-CoV-2. Ultimately, a more advanced surveillance metric for COVID-19 transmission is necessary to help government systems and national leaders understand which responses have been effective and gauge where outbreaks occur. Objective: The goal of this study is to provide advanced COVID-19 surveillance metrics for Canada at the country, province, and territory level that account for shifts in the pandemic including speed, acceleration, jerk, and persistence. Enhanced surveillance identifies risks for explosive growth and regions that have controlled outbreaks successfully. Methods: Using a longitudinal trend analysis study design, we extracted 62 days of COVID-19 data from Canadian public health registries for 13 provinces and territories. We used an empirical difference equation to measure the daily number of cases in Canada as a function of the prior number of cases, the level of testing, and weekly shift variables based on a dynamic panel model that was estimated using the generalized method of moments approach by implementing the Arellano-Bond estimator in R. Results: We compare the week of February 7-13, 2021, with the week of February 14-20, 2021. Canada, as a whole, had a decrease in speed from 8.4 daily new cases per 100,000 population to 7.5 daily new cases per 100,000 population. The persistence of new cases during the week of February 14-20 reported 7.5 cases that are a result of COVID-19 transmissions 7 days earlier. The two most populous provinces of Ontario and Quebec both experienced decreases in speed from 7.9 and 11.5 daily new cases per 100,000 population for the week of February 7-13 to speeds of 6.9 and 9.3 for the week of February 14-20, respectively. Nunavut experienced a significant increase in speed during this time, from 3.3 daily new cases per 100,000 population to 10.9 daily new cases per 100,000 population. Conclusions: Canada excelled at COVID-19 control early on in the pandemic, especially during the first COVID-19 shutdown. The second wave at the end of 2020 resulted in a resurgence of the outbreak, which has since been controlled. Enhanced surveillance identifies outbreaks and where there is the potential for explosive growth, which informs proactive health policy.
- Keyword:
- global COVID surveillance, COVID-19, COVID-21, new COVID strains, Canada Public Health Surveillance, Great COVID Shutdown, Canadian COVID-19, surveillance metrics, wave 2 Canada COVID-19, dynamic panel data, generalized method of the moments, Canadian econometrics, Canada SARS-CoV-2, Canadian COVID-19 surveillance system, Canadian COVID transmission speed, Canadian COVID transmission acceleration, COVID transmission deceleration, COVID transmission jerk, COVID 7-day lag
- Subject: MESH:
- SARS-CoV-2, COVID-19, Public Health Surveillance, Longitudinal Studies, Models, Statistical, Data Interpretation, Statistical
- Subject: Geographic Name:
- Canada, Alberta, British Columbia, Manitoba, New Brunswick, Newfoundland and Labrador, Northwest Territories, Nova Scotia, Nunavut, Ontario, Prince Edward Island, Quebec (Province), Saskatchewan, Yukon Territory
- Creator:
- Post, Lori Ann, Boctor, Michael Jacob, Issa, Tariq Ziad, Moss, Charles B, Murphy, Robert Leo, Achenbach, Chad J, Ison, Michael G, Resnick, Danielle, Singh, Lauren, White, Janine Inui, Welch, Sarah, Oehmke, James Francis
- Publisher:
- JMIR PUBLICATIONS, INC
- Language:
- English
- Date Created:
- 2021-05
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 33852410
- Title:
- Surveillance Metrics of SARS-CoV-2 Transmission in Central Asia: Longitudinal Trend Analysis
- Original Bibliographic Citation:
- Post LA, Benishay ET, Moss CB, Murphy RL, Achenbach CJ, Ison MG, Resnick D, Singh LN, White J, Chaudhury AS, Boctor MJ, Welch SB, Oehmke JF. Surveillance Metrics of SARS-CoV-2 Transmission in Central Asia: Longitudinal Trend Analysis. Journal of Medical Internet Research. 2021;23(2):15.
- Abstract:
- Background: SARS-CoV-2, the virus that caused the global COVID-19 pandemic, has severely impacted Central Asia; in spring 2020, high numbers of cases and deaths were reported in this region. The second wave of the COVID-19 pandemic is currently breaching the borders of Central Asia. Public health surveillance is necessary to inform policy and guide leaders; however, existing surveillance explains past transmissions while obscuring shifts in the pandemic, increases in infection rates, and the persistence of the transmission of COVID-19. Objective: The goal of this study is to provide enhanced surveillance metrics for SARS-CoV-2 transmission that account for weekly shifts in the pandemic, including speed, acceleration, jerk, and persistence, to better understand the risk of explosive growth in each country and which countries are managing the pandemic successfully. Methods: Using a longitudinal trend analysis study design, we extracted 60 days of COVID-19-related data from public health registries. We used an empirical difference equation to measure the daily number of cases in the Central Asia region as a function of the prior number of cases, level of testing, and weekly shift variables based on a dynamic panel model that was estimated using the generalized method of moments approach by implementing the Arellano-Bond estimator in R. Results: COVID-19 transmission rates were tracked for the weeks of September 30 to October 6 and October 7-13, 2020, in Central Asia. The region averaged 11,730 new cases per day for the first week and 14,514 for the second week. Infection rates increased across the region from 4.74 per 100,000 persons to 5.66. Russia and Turkey had the highest 7-day moving averages in the region, with 9836 and 1469, respectively, for the week of October 6 and 12,501 and 1603, respectively, for the week of October 13. Russia has the fourth highest speed in the region and continues to have positive acceleration, driving the negative trend for the entire region as the largest country by population. Armenia is experiencing explosive growth of COVID-19; its infection rate of 13.73 for the week of October 6 quickly jumped to 25.19, the highest in the region, the following week. The region overall is experiencing increases in its 7-day moving average of new cases, infection, rate, and speed, with continued positive acceleration and no sign of a reversal in sight. Conclusions: The rapidly evolving COVID-19 pandemic requires novel dynamic surveillance metrics in addition to static metrics to effectively analyze the pandemic trajectory and control spread. Policy makers need to know the magnitude of transmission rates, how quickly they are accelerating, and how previous cases are impacting current caseload due to a lag effect. These metrics applied to Central Asia suggest that the region is trending negatively, primarily due to minimal restrictions in Russia.
- Keyword:
- SARS-CoV-2 surveillance, second wave, wave two, global COVID-19 surveillance, Central Asia public health surveillance, Central Asia COVID-19, Central Asia surveillance metrics, dynamic panel data, generalized method of moments, Central Asia econometrics, Central Asia SARS-CoV-2, Central Asia COVID-19 surveillance system, Central Asia COVID-19 transmission speed, Central Asia COVID transmission acceleration, COVID-19 transmission deceleration, COVID-19 transmission jerk, COVID-19 7-day lag, SARS-CoV-2, Arellano-Bond estimator, GMM, COVID-19, surveillance, longitudinal, trend, trend analysis, monitoring, public health, infectious disease, transmission, risk, management, policy, prevention
- Subject: MESH:
- SARS-CoV-2, COVID-19, Public Health Surveillance, Longitudinal Studies, Models, Statistical, Data Interpretation, Statistical, Health Policy
- Subject: Geographic Name:
- Armenia, Azerbaijan, Cyprus, Faroe Islands, Georgia (Republic), Gibraltar, Kazakhstan, Kosovo (Republic), Kyrgyzstan, Macedonia (Republic), Russia, Tajikistan, Turkmenistan, Uzbekistan, Turkey
- Creator:
- Post, Lori Ann, Benishay, Elana Tori, Moss, Charles B, Murphy, Robert Leo, Achenbach, Chad J, Ison, Michael G, Resnick, Danielle, Singh, Lauren Nadya, White, Janine Inui, Chaudhury, Azraa Sofia, Boctor, Michael Jacob, Welch, Sarah, Oehmke, James Francis
- Publisher:
- JMIR PUBLICATIONS, INC
- Language:
- English
- Date Created:
- 2021-02-03
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 33475513
- Title:
- What Every Reader Should Know About Studies Using Electronic Health Record Data but May Be Afraid to Ask
- Original Bibliographic Citation:
- Kohane IS, Aronow BJ, Avillach P, Beaulieu-Jones BK, Bellazzi R, Bradford RL, Brat GA, Cannataro M, Cimino JJ, Garcia-Barrio N, Gehlenborg N, Ghassemi M, Gutierrez-Sacristan A, Hanauer DA, Holmes JH, Hong C, Klann JG, Loh NHW, Luo Y, Mandl KD, Daniar M, Moore JH, Murphy SN, Neuraz A, Ngiam KY, Omenn GS, Palmer N, Patel LP, Pedrera-Jimenez M, Sliz P, South AM, Tan ALM, Taylor DM, Taylor BW, Torti C, Vallejos AK, Wagholikar KB, Weber GM, Cai TX, Consortium Clinical C. What Every Reader Should Know About Studies Using Electronic Health Record Data but May Be Afraid to Ask. Journal of Medical Internet Research. 2021;23(3):9.
- Abstract:
- Coincident with the tsunami of COVID-19-related publications, there has been a surge of studies using real-world data, including those obtained from the electronic health record (EHR). Unfortunately, several of these high-profile publications were retracted because of concerns regarding the soundness and quality of the studies and the EHR data they purported to analyze. These retractions highlight that although a small community of EHR informatics experts can readily identify strengths and flaws in EHR-derived studies, many medical editorial teams and otherwise sophisticated medical readers lack the framework to fully critically appraise these studies. In addition, conventional statistical analyses cannot overcome the need for an understanding of the opportunities and limitations of EHR-derived studies. We distill here from the broader informatics literature six key considerations that are crucial for appraising studies utilizing EHR data: data completeness, data collection and handling (eg, transformation), data type (ie, codified, textual), robustness of methods against EHR variability (within and across institutions, countries, and time), transparency of data and analytic code, and the multidisciplinary approach. These considerations will inform researchers, clinicians, and other stakeholders as to the recommended best practices in reviewing manuscripts, grants, and other outputs from EHR-data derived studies, and thereby promote and foster rigor, quality, and reliability of this rapidly growing field.
- Keyword:
- COVID-19, electronic health records, real-world data, literature, publishing, quality, data quality, reporting standards, reporting checklist, review, statistics
- Subject: MESH:
- COVID-19, Electronic Health Records, Data Accuracy, Data Analysis, Review Literature as Topic, Data Interpretation, Statistical
- Creator:
- Kohane, Isaac S., Aronow, Bruce J., Avillach, Paul, Beaulieu-Jones, Brett K., Bellazzi, Riccardo, Bradford, Robert L., Brat, Gabriel A., Cannataro, Mario, Cimino, James J., Garcia-Barrio, Noelia, Gehlenborg, Nils, Ghassemi, Marzyeh, Gutierrez-Sacristan, Alba, Hanauer, David A., Holmes, John H., Hong, Chuan, Klann, Jeffrey G., Loh, Ne Hooi Will, Luo, Yuan, Mandl, Kenneth D., Daniar, Mohamad, Moore, Jason H., Murphy, Shawn N., Neuraz, Antoine, Ngiam, Kee Yuan, Omenn, Gilbert S., Palmer, Nathan, Patel, Lav P., Pedrera-Jimenez, Miguel, Sliz, Piotr, South, Andrew M., Tan, Amelia Li Min, Taylor, Deanne M., Taylor, Bradley W., Torti, Carlo, Vallejos, Andrew K., Wagholikar, Kavishwar B., Weber, Griffin M., Cai, Tianxi, The Consortium For Clinical Characterization Of COVID-19 By EHR (4CE)
- Publisher:
- JMIR PUBLICATIONS, INC
- Language:
- English
- Date Created:
- 2021-03-02
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 33600347
- Title:
- Coronavirus Disease-19: An Interim Evidence Synthesis of the World Association for Infectious Diseases and Immunological Disorders (Waidid)
- Original Bibliographic Citation:
- Abu-Raya B, Migliori GB, O'Ryan M, Edwards K, Torres A, Alffenaar JW, Martson AG, Centis R, D'Ambrosio L, Flanagan K, Hung I, Lauretani F, Leung CC, Leuridan E, Maertens K, Maggio MG, Nadel S, Hens N, Niesters H, Osterhaus A, Pontali E, Principi N, Silva DR, Omer S, Spanevello A, Sverzellati N, Tan TN, Torres-Torreti JP, Visca D, Esposito S. Coronavirus Disease-19: An Interim Evidence Synthesis of the World Association for Infectious Diseases and Immunological Disorders (Waidid). Frontiers in Medicine. 2020;7:20.
- Abstract:
- Coronavirus disease 2019 (COVID-19) is a rapidly evolving, highly transmissible, and potentially lethal pandemic caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). As of June 11 2020, more than 7,000,000 COVID-19 cases have been reported worldwide, and more than 400,000 patients have died, affecting at least 188 countries. While literature on the disease is rapidly accumulating, an integrated, multinational perspective on clinical manifestations, immunological effects, diagnosis, prevention, and treatment of COVID-19 can be of global benefit. We aimed to synthesize the most relevant literature and experiences in different parts of the world through our global consortium of experts to provide a consensus-based document at this early stage of the pandemic.
- Keyword:
- COVID-19, coronavirus, intensive care management, prevention, workplace safety, infection control, SARS-CoV-2, physical distancing
- Subject: MESH:
- COVID-19, SARS-CoV-2, Critical Care, Infection Control
- Creator:
- Abu-Raya, Bahaa, Migliori, Giovanni Battista, O'Ryan, Miguel, Edwards, Kathryn, Torres, Antoni, Alffenaar, Jan-Willem, Martson, Anne-Grete, Centis, Rosella, D'Ambrosio, Lia, Flanagan, Katie, Hung, Ivan, Lauretani, Fulvio, Leung, Chi Chi, Leuridan, Elke, Maertens, Kirsten, Maggio, Marcello Giuseppe, Nadel, Simon, Hens, Niel, Niesters, Hubert, Osterhaus, Albert, Pontali, Emanuele, Principi, Nicola, Rossato Silva, Denise, Omer, Saad, Spanevello, Antonio, Sverzellati, Nicola, Tan, Tina Quanbee, Torres-Torreti, Juan Pablo, Visca, Dina, Esposito, Susanna
- Publisher:
- FRONTIERS MEDIA SA
- Language:
- English
- Date Created:
- 2020-10-30
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Review
- Original Identifier:
- (PMID) 33195319
- Title:
- 2021-2022 Series 08 NUCATS Dealing with Mentoring Challenges
- Description:
- Presentation discusses fundamental components of communicating effectively as a mentor, techniques to promote and facilitate workplace communication, and elements of conversation to deliver positive and negative feedback.
- Keyword:
- NUCATS, Mentoring, Difficult Conversations, Mentoring Relationships
- Subject: MESH:
- Mentoring, Mentors, Communication
- Creator:
- Carnethon, Mercedes R, Michelson, Kelly N
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Language:
- English
- Date Created:
- 2022-05-12
- Rights:
- http://creativecommons.org/licenses/by-nc-nd/3.0/us/, http://creativecommons.org/licenses/by-nc-sa/3.0/us/
- Resource Type:
- Presentation
- Title:
- Reply to COVID-19 encephalopathy, Bayes rule, and a plea for casecontrol studies
- Original Bibliographic Citation:
- Liotta EM, Batra A, Koralnik IJ. Reply to COVID-19 encephalopathy, Bayes rule, and a plea for case-control studies. Annals of Clinical and Translational Neurology. 2021;8(3):726-726.
- Keyword:
- COVID-19
- Subject: MESH:
- COVID-19, Research Design
- Creator:
- Liotta, Eric Michael, Batra, Ayush, Koralnik, Igor Jerome
- Publisher:
- WILEY
- Language:
- English
- Date Created:
- 2021-03
- Rights:
- http://creativecommons.org/licenses/by-nc-nd/3.0/us/
- Resource Type:
- Letter
- Original Identifier:
- (PMID) 33512080
- Title:
- SARS-CoV-2 Wave Two Surveillance in East Asia and the Pacific: Longitudinal Trend Analysis
- Original Bibliographic Citation:
- Post LA, Lin JS, Moss CB, Murphy RL, Ison MG, Achenbach CJ, Resnick D, Singh LN, White J, Boctor MJ, Welch SB, Oehmke JF. SARS-CoV-2 Wave Two Surveillance in East Asia and the Pacific: Longitudinal Trend Analysis. Journal of Medical Internet Research. 2021;23(2):15.
- Abstract:
- Background: The COVID-19 pandemic has had a profound global impact on governments, health care systems, economies, and populations around the world. Within the East Asia and Pacific region, some countries have mitigated the spread of the novel coronavirus effectively and largely avoided severe negative consequences, while others still struggle with containment As the second wave reaches East Asia and the Pacific, it becomes more evident that additional SARS-CoV-2 surveillance is needed to track recent shifts, rates of increase, and persistence associated with the pandemic. Objective: The goal of this study is to provide advanced surveillance metrics for COVID-19 transmission that account for speed, acceleration, jerk, persistence, and weekly shifts, to better understand country risk for explosive growth and those countries who are managing the pandemic successfully. Existing surveillance coupled with our dynamic metrics of transmission will inform health policy to control the COVID-19 pandemic until an effective vaccine is developed. We provide novel indicators to measure disease transmission. Methods: Using a longitudinal trend analysis study design, we extracted 330 days of COVID-19 data from public health registries. We used an empirical difference equation to measure the daily number of cases in East Asia and the Pacific as a function of the prior number of cases, the level of testing, and weekly shift variables based on a dynamic panel model that was estimated using the generalized method of moments approach by implementing the Arellano-Bond estimator in R. Results: The standard surveillance metrics for Indonesia, the Philippines, and Myanmar were concerning as they had the largest new caseloads at 4301, 2588, and 1387, respectively. When looking at the acceleration of new COVID-19 infections, we found that French Polynesia, Malaysia, and the Philippines had rates at 3.17, 0.22, and 0.06 per 100,000. These three countries also ranked highest in terms of jerk at 15.45, 0.10, and 0.04, respectively. Conclusions: Two of the most populous countries in East Asia and the Pacific, Indonesia and the Philippines, have alarming surveillance metrics. These two countries rank highest in new infections in the region. The highest rates of speed, acceleration, and positive upwards jerk belong to French Polynesia, Malaysia, and the Philippines, and may result in explosive growth. While all countries in East Asia and the Pacific need to be cautious about reopening their countries since outbreaks are likely to occur in the second wave of COVID-19, the country of greatest concern is the Philippines. Based on standard and enhanced surveillance, the Philippines has not gained control of the COVID-19 epidemic, which is particularly troubling because the country ranks 4th in population in the region. Without extreme and rigid social distancing, quarantines, hygiene, and masking to reverse trends, the Philippines will remain on the global top 5 list of worst COVID-19 outbreaks resulting in high morbidity and mortality. The second wave will only exacerbate existing conditions and increase COVID-19 transmissions.
- Keyword:
- COVID-19, SARS-CoV-2, SARS-CoV-2 surveillance, second wave, wave two, wave 2, global COVID-19 surveillance, Asia Pacific public health surveillance, Asia Pacific COVID-19, Asian Pacific SARS-CoV-2, Asia Pacific surveillance metrics, dynamic panel data, generalized method of the moments, Asian Pacific econometrics, East Asian Pacific COVID-19 surveillance system, Pacific Asian COVID-19 transmission speed, Asian Pacific COVID-19 transmission acceleration, COVID-19 transmission deceleration, COVID-19 transmission jerk, COVID-19 7-day lag, Arellano-Bond estimator, generalized method of moments, GMM, Myanmar
- Subject: MESH:
- COVID-19, SARS-CoV-2, Public Health Surveillance, Longitudinal Studies, Health Policy
- Subject: Geographic Name:
- Australia, Brunei, Cambodia, China, Fiji, French Polynesia, Guam, Indonesia, Japan, Kiribati, Laos, Malaysia, Mongolia, Burma, New Caledonia, Philippines
- Creator:
- Post, Lori Ann, Lin, Jasmine Samantha, Moss, Charles B, Murphy, Robert Leo, Ison, Michael G, Achenbach, Chad J, Resnick, Danielle, Singh, Lauren Nadya, White, Janine Inui, Boctor, Michael Jacob, Welch, Sarah, Oehmke, James Francis
- Publisher:
- JMIR PUBLICATIONS, INC
- Language:
- English
- Date Created:
- 2021-02-01
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 33464207
- Title:
- Psychosocial Challenges and Opportunities for Youth With Chronic Health Conditions During the COVID-19 Pandemic
- Original Bibliographic Citation:
- Serlachius A, Badawy SM, Thabrew H. Psychosocial Challenges and Opportunities for Youth With Chronic Health Conditions During the COVID-19 Pandemic. Journal of Medical Internet Research. 2020;22(10):8.
- Abstract:
- School closures, altered access to health services, and economic stress during the COVID-19 pandemic have likely had an impact on the mental and physical well-being of youth worldwide, particularly among those with chronic health conditions (CHCs). A number of challenges and opportunities have emerged during the COVID-19 pandemic for youth with CHCs. Challenges include heightened anxiety, disrupted routines, academic and social stresses associated with school closure, increased risk of domestic violence and abuse, and reduced access to physical and psychosocial support. On the other hand, opportunities include reduced academic and social stress, increased time with families, reduced access to substances, easier access to health care using technology, and opportunities to build resilience. This viewpoint paper highlights both challenges and opportunities for youth with CHCs during the pandemic and offers recommendations for further research and clinical care.
- Keyword:
- COVID-19, coronavirus, pandemic, chronic illness, youth, adolescents, children, psychosocial, anxiety
- Subject: MESH:
- COVID-19, Chronic Disease, Adolescent Health, Psychosocial Functioning, Anxiety
- Creator:
- Serlachius, Anna, Badawy, Sherif M, Thabrew, Hiran
- Publisher:
- JMIR PUBLICATIONS, INC
- Language:
- English
- Date Created:
- 2020-10-12
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 33001834
- Title:
- Latin America and the Caribbean SARS-CoV-2 Surveillance: Longitudinal Trend Analysis
- Original Bibliographic Citation:
- Post L, Ohiomoba RO, Maras A, Watts SJ, Moss CB, Murphy RL, Ison MG, Achenbach CJ, Resnick D, Singh LN, White J, Chaudhury AS, Boctor MJ, Welch SB, Oehmke JF. Latin America and the Caribbean SARS-CoV-2 Surveillance: Longitudinal Trend Analysis. Jmir Public Health and Surveillance. 2021;7(4):14.
- Abstract:
- Background: The COVID-19 pandemic has placed unprecedented stress on economies, food systems, and health care resources in Latin America and the Caribbean (LAC). Existing surveillance provides a proxy of the COVID-19 caseload and mortalities; however, these measures make it difficult to identify the dynamics of the pandemic and places where outbreaks are likely to occur. Moreover, existing surveillance techniques have failed to measure the dynamics of the pandemic. Objective: This study aimed to provide additional surveillance metrics for COVID-19 transmission to track changes in the speed, acceleration, jerk, and persistence in the transmission of the pandemic more accurately than existing metrics. Methods: Through a longitudinal trend analysis, we extracted COVID-19 data over 45 days from public health registries. We used an empirical difference equation to monitor the daily number of cases in the LAC as a function of the prior number of cases, the level of testing, and weekly shift variables based on a dynamic panel model that was estimated using the generalized method of moments approach by implementing the Arellano-Bond estimator in R. COVID-19 transmission rates were tracked for the LAC between September 30 and October 6, 2020, and between October 7 and 13, 2020. Results: The LAC saw a reduction in the speed, acceleration, and jerk for the week of October 13, 2020, compared to the week of October 6, 2020, accompanied by reductions in new cases and the 7-day moving average. For the week of October 6, 2020, Belize reported the highest acceleration and jerk, at 1.7 and 1.8, respectively, which is particularly concerning, given its high mortality rate. The Bahamas also had a high acceleration at 1.5. In total, 11 countries had a positive acceleration during the week of October 6, 2020, whereas only 6 countries had a positive acceleration for the week of October 13, 2020. The TAC displayed an overall positive trend, with a speed of 10.40, acceleration of 0.27, and jerk of -0.31, all of which decreased in the subsequent week to 9.04, -0.81, and -0.03, respectively. Conclusions: Metrics such as new cases, cumulative cases, deaths, and 7-day moving averages provide a static view of the pandemic but fail to identify where and the speed at which SARS-CoV-2 infects new individuals, the rate of acceleration or deceleration of the pandemic, and weekly comparison of the rate of acceleration of the pandemic indicate impending explosive growth or control of the pandemic. Enhanced surveillance will inform policymakers and leaders in the LAC about COVID-19 outbreaks.
- Keyword:
- 7-day persistence, acceleration, Arellano-Bond estimator, COVID-19 surveillance system, COVID-19, dynamic panel data, econometrics, economic, generalized method of moments, global COVID-19 surveillance, Latin America and the Caribbean, longitudinal, metric, persistence, policy, public health surveillance, SARS-CoV-2, second wave, surveillance metrics, transmission deceleration, transmission jerk, transmission speed, trend analysis
- Subject: MESH:
- COVID-19, SARS-CoV-2, Public Health Surveillance, Longitudinal Studies, Models, Statistical, Data Interpretation, Statistical, Health Policy
- Subject: Geographic Name:
- Latin America, Caribbean Area
- Creator:
- Post, Lori Ann, Ohiomoba, Ramael Osasogie, Maras, Ashley Francia, Watts, Sean Joseph, Moss, Charles B, Murphy, Robert Leo, Ison, Michael G, Achenbach, Chad J, Resnick, Danielle, Singh, Lauren Nadya, White, Janine Inui, Chaudhury, Azraa Sofia, Boctor, Michael Jacob, Welch, Sarah, Oehmke, James Francis
- Publisher:
- JMIR PUBLICATIONS, INC
- Language:
- English
- Date Created:
- 2021-04
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 33852413
- Title:
- Calantone et al 2022 Fig 4d - NADglo Data
- Keyword:
- immunology
- Creator:
- Calantone, Nina Alexandra
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Rights:
- All rights reserved
- Resource Type:
- Dataset
- Title:
- Dynamic Panel Estimate-Based Health Surveillance of SARS-CoV-2 Infection Rates to Inform Public Health Policy: Model Development and Validation
- Original Bibliographic Citation:
- Oehmke JF, Oehmke TB, Singh LN, Post LA. Dynamic Panel Estimate-Based Health Surveillance of SARS-CoV-2 Infection Rates to Inform Public Health Policy: Model Development and Validation. Journal of Medical Internet Research. 2020;22(9):12.
- Abstract:
- Background: SARS-CoV-2, the novel coronavirus that causes COVID-19, is a global pandemic with higher mortality and morbidity than any other virus in the last 100 years. Without public health surveillance, policy makers cannot know where and how the disease is accelerating, decelerating, and shifting. Unfortunately, existing models of COVID-19 contagion rely on parameters such as the basic reproduction number and use static statistical methods that do not capture all the relevant dynamics needed for surveillance. Existing surveillance methods use data that are subject to significant measurement error and other contaminants. Objective: The aim of this study is to provide a proof of concept of the creation of surveillance metrics that correct for measurement error and data contamination to determine when it is safe to ease pandemic restrictions. We applied state-of-the-art statistical modeling to existing internet data to derive the best available estimates of the state-level dynamics of COVID-19 infection in the United States. Methods: Dynamic panel data (DPD) models were estimated with the Arellano-Bond estimator using the generalized method of moments. This statistical technique enables control of various deficiencies in a data set. The validity of the model and statistical technique was tested. Results: A Wald chi-square test of the explanatory power of the statistical approach indicated that it is valid (chi(2)(10)=1489.84, P<.001), and a Sargan chi-square test indicated that the model identification is valid (chi(2)(946) 935.52, P=.59). The 7-day persistence rate for the week of June 27 to July 3 was 0.5188 (P<.001), meaning that every 10,000 new cases in the prior week were associated with 5188 cases 7 days later. For the week of July 4 to 10, the 7-day persistence rate increased by 0.2691 (P=.003), indicating that every 10,000 new cases in the prior week were associated with 7879 new cases 7 days later. Applied to the reported number of cases, these results indicate an increase of almost 100 additional new cases per day per state for the week of July 4-10. This signifies an increase in the reproduction parameter in the contagion models and corroborates the hypothesis that economic reopening without applying best public health practices is associated with a resurgence of the pandemic. Conclusions: DPD models successfully correct for measurement error and data contamination and are useful to derive surveillance metrics. The opening of America involves two certainties. the country will be COVID-19-free only when there is an effective vaccine, and the social end of the pandemic will occur before the medical end. Therefore, improved surveillance metrics are needed to inform leaders of how to open sections of the United States more safely. DPD models can inform this reopening in combination with the extraction of COVID-19 data from existing websites.
- Keyword:
- COVID-19, models, surveillance, COVID-19 surveillance system, dynamic panel data, infectious disease modeling, reopening America, COVID-19 guidelines, COVID-19 health policy
- Subject: MESH:
- COVID-19, SARS-CoV-2, Public Health Surveillance, Models, Statistical, Data Interpretation, Statistical, Health Policy
- Creator:
- Oehmke, James Francis, Oehmke, Theresa B, Post, Lori Ann, Singh, Lauren Nadya
- Publisher:
- JMIR PUBLICATIONS, INC
- Language:
- English
- Date Created:
- 2020-09-22
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 32915762
- Title:
- Dynamic Panel Surveillance of COVID-19 Transmission in the United States to Inform Health Policy: Observational Statistical Study
- Original Bibliographic Citation:
- Oehmke JF, Moss CB, Singh LN, Oehmke TB, Post LA. Dynamic Panel Surveillance of COVID-19 Transmission in the United States to Inform Health Policy: Observational Statistical Study. Journal of Medical Internet Research. 2020;22(10):20.
- Abstract:
- Background: The Great COVID-19 Shutdown aimed to eliminate or slow the spread of SARS-CoV-2, the virus that causes COVID-19. The United States has no national policy, leaving states to independently implement public health guidelines that are predicated on a sustained decline in COVID-19 cases. Operationalization of sustained decline varies by state and county. Existing models of COVID-19 transmission rely on parameters such as case estimates or R-0 and are dependent on intensive data collection efforts. Static statistical models do not capture all of the relevant dynamics required to measure sustained declines. Moreover, existing COVID-19 models use data that are subject to significant measurement error and contamination. Objective: This study will generate novel metrics of speed, acceleration, jerk, and 7-day lag in the speed of COVID-19 transmission using state government tallies of SARS-CoV-2 infections, including state-level dynamics of SARS-CoV-2 infections. This study provides the prototype for a global surveillance system to inform public health practice, including novel standardized metrics of COVID-19 transmission, for use in combination with traditional surveillance tools. Methods: Dynamic panel data models were estimated with the Arellano-Bond estimator using the generalized method of moments. This statistical technique allows for the control of a variety of deficiencies in the existing data. Tests of the validity of the model and statistical techniques were applied. Results: The statistical approach was validated based on the regression results, which determined recent changes in the pattern of infection. During the weeks of August 17-23 and August 24-30, 2020, there were substantial regional differences in the evolution of the US pandemic. Census regions 1 and 2 were relatively quiet with a small but significant persistence effect that remained relatively unchanged from the prior 2 weeks. Census region 3 was sensitive to the number of tests administered, with a high constant rate of cases. A weekly special analysis showed that these results were driven by states with a high number of positive test reports from universities. Census region 4 had a high constant number of cases and a significantly increased persistence effect during the week of August 24-30. This change represents an increase in the transmission model R value for that week and is consistent with a re-emergence of the pandemic. Conclusions: Reopening the United States comes with three certainties: (1) the social end of the pandemic and reopening are going to occur before the medical end even while the pandemic is growing. We need improved standardized surveillance techniques to inform leaders when it is safe to open sections of the country; (2) varying public health policies and guidelines unnecessarily result in varying degrees of transmission and outbreaks; and (3) even those states most successful in containing the pandemic continue to see a small but constant stream of new cases daily.
- Keyword:
- COVID-19, models, surveillance, reopening America, contagion, metrics, health policy, public health
- Subject: MESH:
- COVID-19, SARS-CoV-2, Public Health Surveillance, Health Policy, Models, Statistical, Data Interpretation, Statistical
- Subject: Geographic Name:
- United States
- Creator:
- Oehmke, James Francis, Moss, Charles B., Singh, Lauren Nadya, Oehmke, Theresa Bristol, Post, Lori Ann
- Publisher:
- JMIR PUBLICATIONS, INC
- Language:
- English
- Date Created:
- 2020-10-05
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 32924962
- Title:
- Dynamic Panel Data Modeling and Surveillance of COVID-19 in Metropolitan Areas in the United States: Longitudinal Trend Analysis
- Original Bibliographic Citation:
- Oehmke TB, Post LA, Moss CB, Issa TZ, Boctor MJ, Welch SB, Oehmke JF. Dynamic Panel Data Modeling and Surveillance of COVID-19 in Metropolitan Areas in the United States: Longitudinal Trend Analysis. Journal of Medical Internet Research. 2021;23(2):12.
- Abstract:
- Background: The COVID-19 pandemic has had profound and differential impacts on metropolitan areas across the United States and around the world. Within the United States, metropolitan areas that were hit earliest with the pandemic and reacted with scientifically based health policy were able to contain the virus by late spring. For other areas that kept businesses open, the first wave in the United States hit in mid-summer. As the weather turns colder, universities resume classes, and people tire of lockdowns, a second wave is ascending in both metropolitan and rural areas. It becomes more obvious that additional SARS-CoV-2 surveillance is needed at the local level to track recent shifts in the pandemic, rates of increase, and persistence. Objective: The goal of this study is to provide advanced surveillance metrics for COVID-19 transmission that account for speed, acceleration, jerk and persistence, and weekly shifts, to better understand and manage risk in metropolitan areas. Existing surveillance measures coupled with our dynamic metrics of transmission will inform health policy to control the COVID-19 pandemic until, and after, an effective vaccine is developed. Here, we provide values for novel indicators to measure COVID-19 transmission at the metropolitan area level. Methods: Using a longitudinal trend analysis study design, we extracted 260 days of COVID-19 data from public health registries. We used an empirical difference equation to measure the daily number of cases in the 25 largest US metropolitan areas as a function of the prior number of cases and weekly shift variables based on a dynamic panel data model that was estimated using the generalized method of moments approach by implementing the Arellano-Bond estimator in R. Results: Minneapolis and Chicago have the greatest average number of daily new positive results per standardized 100,000 population (which we refer to as speed). Extreme behavior in Minneapolis showed an increase in speed from 17 to 30 (67%) in 1 week. The jerk and acceleration calculated for these areas also showed extreme behavior. The dynamic panel data model shows that Minneapolis, Chicago, and Detroit have the largest persistence effects, meaning that new cases pertaining to a specific week are statistically attributable to new cases from the prior week. Conclusions: Three of the metropolitan areas with historically early and harsh winters have the highest persistence effects out of the top 25 most populous metropolitan areas in the United States at the beginning of their cold weather season. With these persistence effects, and with indoor activities becoming more popular as the weather gets colder, stringent COVID-19 regulations will be more important than ever to flatten the second wave of the pandemic. As colder weather grips more of the nation, southern metropolitan areas may also see large spikes in the number of cases.
- Keyword:
- COVID-19, SARS-CoV-2, SARS-CoV-2 surveillance, second wave, wave two, wave 2, global COVID-19 surveillance, COVID-19 metropolitan areas, COVID-19 cities, US public health surveillance, US COVID-19, US surveillance metrics, dynamic panel data, generalized method of the moments, US econometrics, US SARS-CoV-2, US COVID-19 surveillance system, US COVID-19 transmission speed, US COVID-19 transmission acceleration, COVID-19 transmission deceleration, COVID-19 transmission jerk, COVID-19 7-day lag, Arellano-Bond estimator, generalized method of moments, GMM, New York City, Los Angeles, Chicago, Dallas, Houston, Washington DC, Miami, Philadelphia, Atlanta, Phoenix, Boston, San Francisco, Riverside, Detroit, Seattle, Minneapolis, San Diego, Tampa, Denver, St Louis, Baltimore, Charlotte, Orlando, San Antonio, Portland
- Subject: MESH:
- COVID-19, Public Health Surveillance, Models, Econometric, Disease Transmission, Infectious
- Subject: Geographic Name:
- United States
- Creator:
- Oehmke, Theresa B., Post, Lori Ann, Moss, Charles B., Issa, Tariq Ziad, Boctor, Michael Jacob, Welch, Sarah B., Oehmke, James Francis
- Publisher:
- JMIR PUBLICATIONS, INC
- Language:
- English
- Date Created:
- 2021-02-09
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 33481757
- Title:
- Dynamic Public Health Surveillance to Track and Mitigate the US COVID-19 Epidemic: Longitudinal Trend Analysis Study
- Original Bibliographic Citation:
- Post LA, Issa TZ, Boctor MJ, Moss CB, Murphy RL, Ison MG, Achenbach CJ, Resnick D, Singh LN, White J, Faber JMM, Culler K, Brandt CA, Oehmke JF. Dynamic Public Health Surveillance to Track and Mitigate the US COVID-19 Epidemic: Longitudinal Trend Analysis Study. Journal of Medical Internet Research. 2020;22(12):14.
- Abstract:
- Background: The emergence of SARS-CoV-2, the virus that causes COVID-19, has led to a global pandemic. The United States has been severely affected, accounting for the most COVID-19 cases and deaths worldwide. Without a coordinated national public health plan informed by surveillance with actionable metrics, the United States has been ineffective at preventing and mitigating the escalating COVID-19 pandemic. Existing surveillance has incomplete ascertainment and is limited by the use of standard surveillance metrics. Although many COVID-19 data sources track infection rates, informing prevention requires capturing the relevant dynamics of the pandemic. Objective: The aim of this study is to develop dynamic metrics for public health surveillance that can inform worldwide COVID-19 prevention efforts. Advanced surveillance techniques are essential to inform public health decision making and to identify where and when corrective action is required to prevent outbreaks. Methods: Using a longitudinal trend analysis study design, we extracted COVID-19 data from global public health registries. We used an empirical difference equation to measure daily case numbers for our use case in 50 US states and the District of Colombia as a function of the prior number of cases, the level of testing, and weekly shift variables based on a dynamic panel model that was estimated using the generalized method of moments approach by implementing the Arellano-Bond estimator in R. Results: Examination of the United States and state data demonstrated that most US states are experiencing outbreaks as measured by these new metrics of speed, acceleration, jerk, and persistence. Larger US states have high COVID-19 caseloads as a function of population size, density, and deficits in adherence to public health guidelines early in the epidemic, and other states have alarming rates of speed, acceleration, jerk, and 7-day persistence in novel infections. North and South Dakota have had the highest rates of COVID-19 transmission combined with positive acceleration, jerk, and 7-day persistence. Wisconsin and Illinois also have alarming indicators and already lead the nation in daily new COVID-19 infections. As the United States enters its third wave of COVID-19, all 50 states and the District of Colombia have positive rates of speed between 7.58 (Hawaii) and 175.01 (North Dakota), and persistence, ranging from 4.44 (Vermont) to 195.35 (North Dakota) new infections per 100,000 people. Conclusions: Standard surveillance techniques such as daily and cumulative infections and deaths are helpful but only provide a static view of what has already occurred in the pandemic and are less helpful in prevention. Public health policy that is informed by dynamic surveillance can shift the country from reacting to COVID-19 transmissions to being proactive and taking corrective action when indicators of speed, acceleration, jerk, and persistence remain positive week over week. Implicit within our dynamic surveillance is an early warning system that indicates when there is problematic growth in COVID-19 transmissions as well as signals when growth will become explosive without action. A public health approach that focuses on prevention can prevent major outbreaks in addition to endorsing effective public health policies. Moreover, subnational analyses on the dynamics of the pandemic allow us to zero in on where transmissions are increasing, meaning corrective action can be applied with precision in problematic areas. Dynamic public health surveillance can inform specific geographies where quarantines are necessary while preserving the economy in other US areas.
- Keyword:
- global COVID-19 surveillance, United States public health surveillance, US COVID-19, surveillance metrics, dynamic panel data, generalized method of the moments, United States econometrics, US SARS-CoV-2, US COVID-19 surveillance system, US COVID-19 transmission speed, COVID-19 transmission acceleration, COVID-19 speed, COVID-19 acceleration, COVID-19 jerk, COVID-19 persistence, Arellano-Bond estimator, COVID-19
- Subject: MESH:
- COVID-19, SARS-CoV-2, Public Health Surveillance, Longitudinal Studies, Models, Statistical, Data Interpretation, Statistical, Health Policy
- Subject: Geographic Name:
- United States
- Creator:
- Post, Lori Ann, Issa, Tariq Ziad, Boctor, Michael Jacob, Moss, Charles B, Murphy, Robert Leo, Ison, Michael G, Achenbach, Chad J, Resnick, Danielle, Singh, Lauren Nadya, White, Janine Inui, Faber, Joshua Marco, Culler, Kasen Lyndell, Brandt, Cynthia A, Oehmke, James Francis
- Publisher:
- JMIR PUBLICATIONS, INC
- Language:
- English
- Date Created:
- 2020-12-03
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 33216726
- Title:
- Using Tweets to Understand How COVID-19-Related Health Beliefs Are Affected in the Age of Social Media: Twitter Data Analysis Study
- Original Bibliographic Citation:
- Wang HY, Li YK, Hutch M, Naidech A, Luo Y. Using Tweets to Understand How COVID-19-Related Health Beliefs Are Affected in the Age of Social Media: Twitter Data Analysis Study. Journal of Medical Internet Research. 2021;23(2):15.
- Abstract:
- Background: The emergence of SARS-CoV-2 (ie, COVID-19) has given rise to a global pandemic affecting 215 countries and over 40 million people as of October 2020. Meanwhile, we are also experiencing an infodemic induced by the overabundance of information, some accurate and some inaccurate, spreading rapidly across social media platforms. Social media has arguably shifted the information acquisition and dissemination of a considerably large population of internet users toward higher interactivities. Objective: This study aimed to investigate COVID-19-related health beliefs on one of the mainstream social media platforms, Twitter, as well as potential impacting factors associated with fluctuations in health beliefs on social media. Methods: We used COVID-19-related posts from the mainstream social media platform Twitter to monitor health beliefs. A total of 92,687,660 tweets corresponding to 8,967,986 unique users from January 6 to June 21, 2020, were retrieved. To quantify health beliefs, we employed the health belief model (HBM) with four core constructs: perceived susceptibility, perceived severity, perceived benefits, and perceived barriers. We utilized natural language processing and machine learning techniques to automate the process of judging the conformity of each tweet with each of the four HBM constructs. A total of 5000 tweets were manually annotated for training the machine learning architectures. Results: The machine learning classifiers yielded areas under the receiver operating characteristic curves over 0.86 for the classification of all four HBM constructs. Our analyses revealed a basic reproduction number R(0 )of 7.62 for trends in the number of Twitter users posting health belief-related content over the study period. The fluctuations in the number of health belief-related tweets could reflect dynamics in case and death statistics, systematic interventions, and public events. Specifically, we observed that scientific events, such as scientific publications, and nonscientific events, such as politicians' speeches, were comparable in their ability to influence health belief trends on social media through a Kruskal-Wallis test (P=.78 and P=.92 for perceived benefits and perceived barriers, respectively). Conclusions: As an analogy of the classic epidemiology model where an infection is considered to be spreading in a population with an R-0 greater than 1, we found that the number of users tweeting about COVID-19 health beliefs was amplifying in an epidemic manner and could partially intensify the infodemic. It is unhealthy that both scientific and nonscientific events constitute no disparity in impacting the health belief trends on Twitter, since nonscientific events, such as politicians' speeches, might not be endorsed by substantial evidence and could sometimes be misleading.
- Keyword:
- COVID-19, social media, health belief, Twitter, infodemic, infodemiology, machine learning, natural language processing
- Subject: MESH:
- COVID-19, Social Media, Health Belief Model, Infodemic, Machine Learning, Natural Language Processing
- Creator:
- Wang, Hanyin, LI, YIKUAN, Hutch, Meghan Rose, Naidech, Andrew M, Luo, Yuan
- Publisher:
- JMIR PUBLICATIONS, INC
- Language:
- English
- Date Created:
- 2021-02-22
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 33529155
- Title:
- Surveillance of the Second Wave of COVID-19 in Europe: Longitudinal Trend Analyses
- Original Bibliographic Citation:
- Post L, Culler K, Moss CB, Murphy RL, Achenbach CJ, Ison MG, Resnick D, Singh LN, White J, Boctor MJ, Welch SB, Oehmke JF. Surveillance of the Second Wave of COVID-19 in Europe: Longitudinal Trend Analyses. Jmir Public Health and Surveillance. 2021;7(4):16.
- Abstract:
- Background: The COVID-19 pandemic has severely impacted Europe, resulting in a high caseload and deaths that varied by country. The second wave of the COVID-19 pandemic has breached the borders of Europe. Public health surveillance is necessary to inform policy and guide leaders. Objective: This study aimed to provide advanced surveillance metrics for COVID-19 transmission that account for weekly shifts in the pandemic, speed, acceleration, jerk, and persistence, to better understand countries at risk for explosive growth and those that are managing the pandemic effectively. Methods: We performed a longitudinal trend analysis and extracted 62 days of COVID-19 data from public health registries. We used an empirical difference equation to measure the daily number of cases in Europe as a function of the prior number of cases, the level of testing, and weekly shift variables based on a dynamic panel model that was estimated using the generalized method of moments approach by implementing the Arellano-Bond estimator in R. Results: New COVID-19 cases slightly decreased from 158,741 (week 1, January 4-10, 2021) to 152,064 (week 2, January 11-17, 2021), and cumulative cases increased from 22,507,271 (week 1) to 23,890,761 (week 2), with a weekly increase of 1,383,490 between January 10 and January 17. France, Germany, Italy, Spain, and the United Kingdom had the largest 7-day moving averages for new cases during week 1. During week 2, the 7-day moving average for France and Spain increased. From week 1 to week 2, the speed decreased (37.72 to 33.02 per 100,000), acceleration decreased (0.39 to -0.16 per 100,000), and jerk increased (-1.30 to 1.37 per 100,000). Conclusions: The United Kingdom, Spain, and Portugal, in particular, are at risk for a rapid expansion in COVID-19 transmission. An examination of the European region suggests that there was a decrease in the COVID-19 caseload between January 4 and January 17, 2021. Unfortunately, the rates of jerk, which were negative for Europe at the beginning of the month, reversed course and became positive, despite decreases in speed and acceleration. Finally, the 7-day persistence rate was higher during week 2 than during week 1. These measures indicate that the second wave of the pandemic may be subsiding, but some countries remain at risk for new outbreaks and increased transmission in the absence of rapid policy responses.
- Keyword:
- SARS-CoV-2 surveillance, wave two, second wave, global COVID surveillance, Europe Public Health Surveillance, Europe COVID, Europe surveillance metrics, dynamic panel data, generalized method of the moments, Europe econometrics, Europe SARS-CoV-2, Europe COVID surveillance system, European COVID transmission speed, European COVID transmission acceleration, COVID transmission deceleration, COVID transmission jerk, COVID 7-day lag, SARS-CoV-2, Arellano-Bond estimator, GMM
- Subject: MESH:
- COVID-19, SARS-CoV-2, Public Health Surveillance, Longitudinal Studies, Models, Statistical, Data Interpretation, Statistical, Health Policy
- Subject: Geographic Name:
- Albania, Andorra, Austria, Belarus, Belgium, Bosnia and Herzegovina, Bulgaria, Croatia, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Greenland, Hungary, Iceland, Ireland, Isle of Man, Italy, Latvia, Liechtenstein, Lithuania, Luxembourg, Moldova, Monaco, Montenegro, Netherlands, Norway, Poland, Portugal, Romania, San Marino, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland, Ukraine, Great Britain, Vatican City
- Creator:
- Post, Lori Ann, Culler, Kasen Lyndell, Moss, Charles B, Murphy, Robert Leo, Achenbach, Chad J, Ison, Michael G, Resnick, Danielle, Singh, Lauren Nadya, White, Janine Inui, Boctor, Michael Jacob, Welch, Sarah, Oehmke, James Francis
- Publisher:
- JMIR PUBLICATIONS, INC
- Language:
- English
- Date Created:
- 2021-04
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 33818391
83. Factors Associated With Intubation and Prolonged Intubation in Hospitalized Patients With COVID-19
- Title:
- Factors Associated With Intubation and Prolonged Intubation in Hospitalized Patients With COVID-19
- Original Bibliographic Citation:
- Hur K, Price CPE, Gray EL, Gulati RK, Maksimoski M, Racette SD, Schneider AL, Khanwalkar AR. Factors Associated With Intubation and Prolonged Intubation in Hospitalized Patients With COVID-19. Otolaryngology-Head and Neck Surgery. 2020;163(1):170-178.
- Abstract:
- Objective To identify risk factors associated with intubation and time to extubation in hospitalized patients with coronavirus disease 2019 (COVID-19). Study Design Retrospective observational study. Setting Ten hospitals in the Chicago metropolitan area. Subjects and Methods Patients with laboratory-confirmed COVID-19 admitted between March 1 and April 8, 2020, were included. We evaluated sociodemographic and clinical characteristics associated with intubation and prolonged intubation for acute respiratory failure secondary to COVID-19 infection. Results Of the 486 hospitalized patients included in the study, the median age was 59 years (interquartile range, 47-69); 271 (55.8%) were male; and the median body mass index was 30.6 (interquartile range, 26.5-35.6). During the hospitalization, 138 (28.4%) patients were intubated; 78 (56.5%) were eventually extubated; 21 (15.2%) died; and 39 (28.3%) remained intubated at a mean +/- SD follow-up of 19.6 +/- 6.7 days. Intubated patients had a significantly higher median age (65 vs 57 years, P < .001) and rate of diabetes (56 [40.6%] vs 104 [29.9%], P = .031) as compared with nonintubated patients. Multivariable logistic regression analysis identified age, sex, respiratory rate, oxygen saturation, history of diabetes, and shortness of breath as factors predictive of intubation. Age and body mass index were the only factors independently associated with time to extubation. Conclusion In addition to clinical signs of respiratory distress, patients with COVID-19 who are older, male, or diabetic are at higher risk of requiring intubation. Among intubated patients, older and more obese patients are at higher risk for prolonged intubation. Otolaryngologists consulted for airway management should consider these factors in their decision making.
- Keyword:
- COVID-19, SARS-CoV-2, coronavirus, hospitalized, adults, mechanical ventilator, intubation, tracheostomy
- Subject: MESH:
- COVID-19, SARS-CoV-2, Hospitalization, Intubation, Tracheostomy, Ventilators, Mechanical
- Subject: Geographic Name:
- Illinois--Chicago
- Creator:
- Hur, Kevin, Price, Caroline P E, Gray, Elizabeth Lucia, Gulati, Reeti Kiran, Maksimoski, Matthew Thomas, Racette, Samuel David, Schneider, Alexander Louis, Khanwalkar, Ashoke R
- Publisher:
- SAGE PUBLICATIONS INC
- Language:
- English
- Date Created:
- 2020-07
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 32423368
- Title:
- Emergency Department Patient Experiences During the COVID-19 Pandemic
- Original Bibliographic Citation:
- Karalius VP, Kaskar SB, Levine DA, Darling TA, Loftus TM, McCarthy DM. Emergency Department Patient Experiences During the COVID-19 Pandemic. Journal of Patient Experience. 2021;8:7.
- Abstract:
- Emergency department (ED) utilization changed notably during the coronavirus disease 2019 (COVID-19) pandemic in the United States. The purpose of the study was to gain a more thorough understanding of ED patient experience during the early stages of the COVID-19 pandemic. This study used the consensual qualitative approach to analyze open-ended responses from post-ED patient experience surveys from February through July 2020. Comments were included in the analysis if they pertained to care during the pandemic (eg, mentioned the virus, masks, PPE). A total of 242 COVID-specific comments from 192 unique patients were analyzed (median age 49 years; 69% female). Six themes were identified: visually observed changes, experiences of process changes, expressions of understanding or appreciation, sense of security, COVID-19 disease-specific comments, and classic satisfaction comments that align with previous literature on patient experience. The COVID-19 pandemic has challenged health care systems across the world in unique and unprecedented ways. This study identified six themes that better elucidate ED patient experience during an unprecedented public health crisis.
- Keyword:
- COVID, coronavirus, emergency department, patient, satisfaction, experience
- Subject: MESH:
- COVID-19, Emergency Service, Hospital, Patient Reported Outcome Measures, Qualitative Research
- Subject: Geographic Name:
- United States
- Creator:
- Karalius, Vytas Petras, Kaskar, Saabir, Levine, Daniel Adam, Darling, Tiffani A, Loftus, Timothy Michael, McCarthy, Danielle Molloy
- Publisher:
- SAGE PUBLICATIONS INC
- Language:
- English
- Date Created:
- 2021-07-23
- Rights:
- http://creativecommons.org/licenses/by-nc/3.0/us/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 34368429
- Title:
- A Timely Call to Arms: COVID-19, the Circadian Clock, and Critical Care
- Original Bibliographic Citation:
- Haspel J, Kim M, Zee P, Schwarzmeier T, Montagnese S, Panda S, Albani A, Merrow M. A Timely Call to Arms: COVID-19, the Circadian Clock, and Critical Care. Journal of Biological Rhythms. 2021;36(1):55-70.
- Abstract:
- We currently find ourselves in the midst of a global coronavirus disease 2019 (COVID-19) pandemic, caused by the highly infectious novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we discuss aspects of SARS-CoV-2 biology and pathology and how these might interact with the circadian clock of the host. We further focus on the severe manifestation of the illness, leading to hospitalization in an intensive care unit. The most common severe complications of COVID-19 relate to clock-regulated human physiology. We speculate on how the pandemic might be used to gain insights on the circadian clock but, more importantly, on how knowledge of the circadian clock might be used to mitigate the disease expression and the clinical course of COVID-19.
- Keyword:
- SARS-CoV-2, COVID-19, circadian clock, critical care, nutrition, zeitgeber, rhythm
- Subject: MESH:
- SARS-CoV-2, Circadian Clocks, Circadian Rhythm, COVID-19
- Subject: LCSH:
- COVID-19 (Disease), Circadian rhythms
- Creator:
- Haspel, Jeffrey, Kim, Minjee, Zee, Phyllis C, Schwarzmeier, Tanja, Montagnese, Sara, Panda, Satchidananda, Albani, Adriana, Merrow, Martha
- Publisher:
- SAGE PUBLICATIONS INC
- Language:
- English
- Date Created:
- 2021-02
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Review
- Original Identifier:
- (PMID) 33573430
- Title:
- Comorbid Medical Conditions in Young Athletes: Considerations for Preparticipation Guidance During the COVID-19 Pandemic
- Original Bibliographic Citation:
- Harmon KG, Pottinger PS, Baggish AL, Drezner JA, Luks AM, Thompson AA, Swaminathan S. Comorbid Medical Conditions in Young Athletes: Considerations for Preparticipation Guidance During the COVID-19 Pandemic. Sports Health-a Multidisciplinary Approach. 2020;12(5):456-458.
- Keyword:
- COVID-19, athlete, obesity, diabetes, asthma
- Subject: MESH:
- COVID-19, Athletes, Comorbidity, Asthma, Obesity
- Creator:
- Pottinger, Paul S, Harmon, Kimberly G, Baggish, Aaron L, Drezner, Jonathan A, Luks, Andrew M, Thompson, Alexis A, Swaminathan, Sankar
- Publisher:
- SAGE PUBLICATIONS INC
- Language:
- English
- Date Created:
- 2020-09
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 32579436
- Title:
- Resumption of Sport at the United States Olympic and Paralympic Training Facilities During the COVID-19 Pandemic
- Original Bibliographic Citation:
- Shah AB, Nabhan D, Chapman R, Chiampas G, Drezner J, Olin JT, Taylor D, Finnoff JT, Baggish AL. Resumption of Sport at the United States Olympic and Paralympic Training Facilities During the COVID-19 Pandemic. Sports Health-a Multidisciplinary Approach. 2021;13(4):359-363.
- Abstract:
- In this brief report, we describe the safety of reopening US Olympic and Paralympic Training facilities (USOPTFs) during the coronavirus disease 2019 (COVID-19) pandemic from July 2020 through October 2020. We evaluated the prevalence of COVID-19 infection at the time of reentry and cardiopulmonary sequelae of COVID-19 in elite athletes. All athletes returning to a USOPTF were required to go through a reentry protocol consisting of an electronic health history, a 6-day quarantine including twice-daily symptom surveys, COVID-19 polymerase chain reaction and antibody testing, physical examination, 12-lead electrocardiogram, high-sensitivity cardiac troponin I, and pulmonary function testing. Athletes with current or prior COVID-19 infection also underwent an echocardiogram, cardiology consultation, and additional testing as indicated. All athletes followed rigorous infection prevention measures and minimized contact with the outside community following reentry. At the time of this report, 301 athletes completed the reentry protocol among which 14 (4.7%) tested positive for active (positive polymerase chain reaction test, n = 3) or prior (positive antibody test, n = 11) COVID-19 infection. During the study period, this cohort accrued 14,916 days living and training at USOPTFs. Only one (0.3%) athlete was subsequently diagnosed with a new COVID-19 infection. No cardiopulmonary pathology attributable to COVID-19 was detected. Our findings suggest that residential elite athlete training facilities can successfully resume activity during the COVID-19 pandemic when strict reentry and infection prevention measures are followed. Dissemination of our reentry quarantine and screening protocols with COVID-19 mitigation measures may assist the global sports and medical community develop best practices for reopening of similar training centers.
- Keyword:
- elite athlete training, COVID-19, myocardial injury, return-to-play
- Subject: MESH:
- COVID-19, Athletes, Myocardial Contusions
- Subject: Geographic Name:
- United States
- Creator:
- Shah, Ankit B, Nabhan, Dustin, Chapman, Robert Scott, Chiampas, George T, Drezner, Jonathan, Olin, J. Tod, Taylor, David E, Finnoff, Jonathan T, Baggish, Aaron L
- Publisher:
- SAGE PUBLICATIONS INC
- Language:
- English
- Date Created:
- 2021-07
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 33709838
- Title:
- Comprehensive Literature Review and Evidence evaluation of Experimental Treatment in COVID 19 Contagion
- Original Bibliographic Citation:
- Boregowda U, Gandhi D, Jain N, Khanna K, Gupta N. Comprehensive Literature Review and Evidence evaluation of Experimental Treatment in COVID 19 Contagion. Clinical Medicine Insights-Circulatory Respiratory and Pulmonary Medicine. 2020;14:7.
- Abstract:
- IMPORTANCE: Coronavirus 2019 pandemic (COVID 19) is caused by the Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) virus. The pandemic is affecting the livelihood of millions of people all over the world. At the time of preparing this report, the pandemic has affected 1 827 284 patients, with 113 031 deaths in 185 countries as per Johns Hopkins University. With no proven treatment for the disease, prevention of the disease in the community and healthcare setting is need of the hour. OBJECTIVE: To perform a comprehensive literature search for preventive measures and experimental treatment options. In this review, we have focused our discussion on the risk of disease transmission, supportive treatment, and possible treatment options based on available evidence. EVIDENCE REVIEW: We performed a literature search on google scholar, PubMed, and society guidelines for literature related to COVID 19 and previous coronavirus pandemics. We included data review articles, observational studies, and controlled trials to synthesize the treatment options for COVID 19. FINDINGS: In this article, we have extensively reviewed and discussed recommendations from various world organizations for the public and healthcare workers. We have also discussed currently available experimental treatments since there is no proven treatment for COVID 19. The best method of dealing with the current outbreak is to reduce the community spread and thus flatten the curve. Although Hydroxychloroquine, Remdesivir, Lopinavir/Ritonavir, and Azithromycin have been tried, passive immunity through convalescent serum and vaccine is still at an experimental stage. Patients with severe COVID 19 infections could be considered for this experimental treatment through various national randomized control trials, which may eventually lead to an evidence-based treatment strategy. CONCLUSIONS AND RELEVANCE: Awareness of currently available experimental treatment among healthcare providers and exploration of possible treatment options through evidence is need of the hour. We have discussed the most recently available literature and evidence behind experimental treatment in this article.
- Keyword:
- COVID-19, coronavirus, Wuhan, Remdesivir, pandemic, RT-PCR
- Subject: MESH:
- COVID-19, Biomedical Research
- Creator:
- Boregowda, Umesha, Gandhi, Darshan, Jain, Nitin, Khanna, Kanika, Gupta, Nishant
- Publisher:
- SAGE PUBLICATIONS LTD
- Language:
- English
- Date Created:
- 2020-10
- Rights:
- http://creativecommons.org/licenses/by-sa/3.0/us/
- Resource Type:
- Review
- Original Identifier:
- (PMID) 35173507
- Title:
- Coping With Health Threats: The Costs and Benefits of Managing Emotions
- Original Bibliographic Citation:
- Smith AM, Willroth EC, Gatchpazian A, Shallcross AJ, Feinberg M, Ford BQ. Coping With Health Threats: The Costs and Benefits of Managing Emotions. Psychological Science. 2021;32(7):1011-1023.
- Abstract:
- How people respond to health threats can influence their own health and, when people are facing communal risks, even their community's health. We propose that people commonly respond to health threats by managing their emotions with cognitive strategies such as reappraisal, which can reduce fear and protect mental health. However, because fear can also motivate health behaviors, reducing fear may also jeopardize health behaviors. In two diverse U.S. samples (N = 1,241) tracked across 3 months, sequential and cross-lagged panel mediation models indicated that reappraisal predicted lower fear about an ongoing health threat (COVID-19) and, in turn, better mental health but fewer recommended physical health behaviors. This trade-off was not inevitable, however: The use of reappraisal to increase socially oriented positive emotions predicted better mental health without jeopardizing physical health behaviors. Examining the costs and benefits of how people cope with health threats is essential for promoting better health outcomes for individuals and communities.
- Keyword:
- emotion regulation, reappraisal, fear, positive emotions, health behaviors, mental health, COVID-19, open data, open materials
- Subject: MESH:
- COVID-19, Emotional Regulation, Fear, Health Behavior, Mental Health
- Creator:
- Smith, Angela M, Willroth, Emily Catherine, Gatchpazian, Arasteh, Shallcross, Amanda J, Feinberg, Matthew, Ford, Brett Q
- Publisher:
- SAGE PUBLICATIONS INC
- Language:
- English
- Date Created:
- 2021-07
- Rights:
- http://creativecommons.org/licenses/by-nc/3.0/us/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 34143697
- Title:
- Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors
- Original Bibliographic Citation:
- Devkota K, Schapira M, Perveen S, Yazdi AK, Li FL, Chau I, Ghiabi P, Hajian T, Loppnau P, Bolotokova A, Satchell KJF, Wang K, Li DY, Liu J, Smil D, Luo MK, Jin J, Fish PV, Brown PJ, Vedadi M. Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors. Slas Discovery. 2021;26(9):1200-1211.
- Abstract:
- The COVID-19 pandemic has clearly brought the healthcare systems worldwide to a breaking point, along with devastating socioeconomic consequences. The SARS-CoV-2 virus, which causes the disease, uses RNA capping to evade the human immune system. Nonstructural protein (nsp) 14 is one of the 16 nsps in SARS-CoV-2 and catalyzes the methylation of the viral RNA at N7-guanosine in the cap formation process. To discover small-molecule inhibitors of nsp14 methyltransferase (MTase) activity, we developed and employed a radiometric MTase assay to screen a library of 161 in-house synthesized S-adenosylmethionine (SAM) competitive MTase inhibitors and SAM analogs. Among six identified screening hits, SS148 inhibited nsp14 MTase activity with an IC50 value of 70 +/- 6 nM and was selective against 20 human protein lysine MTases, indicating significant differences in SAM binding sites. Interestingly, DS0464 with an IC50 value of 1.1 +/- 0.2 mu M showed a bisubstrate competitive inhibitor mechanism of action. DS0464 was also selective against 28 out of 33 RNA, DNA, and protein MTases. The structure-activity relationship provided by these compounds should guide the optimization of selective bisubstrate nsp14 inhibitors and may provide a path toward a novel class of antivirals against COVID-19, and possibly other coronaviruses.
- Keyword:
- COVID-19, nsp14, SARS-CoV-2, coronavirus
- Subject: MESH:
- SARS-CoV-2, COVID-19, S-Adenosylmethionine, Binding Sites
- Creator:
- Devkota, Kanchan, Schapira, Matthieu, Perveen, Sumera, Yazdi, Aliakbar Khalili, Li, Fengling, Chau, Irene, Ghiabi, Pegah, Hajian, Taraneh, Loppnau, Peter, Bolotokova, Albina, Satchell, Karla J. F., Wang, Ke, Li, Deyao, Liu, Jing, Smil, David, Luo, Minkui, Jin, Jian, Fish, Paul, V., Brown, Peter J., Vedadi, Masoud
- Publisher:
- SAGE PUBLICATIONS INC
- Language:
- English
- Date Created:
- 2021-10
- Rights:
- http://creativecommons.org/licenses/by-nc/3.0/us/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 34192965
- Title:
- A Framework for Maintaining a Fully Operational Autopsy Service at a Large Academic Teaching Institution During a Global Pandemic
- Original Bibliographic Citation:
- Fu L, Zak T, Shanes E. A Framework for Maintaining a Fully Operational Autopsy Service at a Large Academic Teaching Institution During a Global Pandemic. Academic Pathology. 2021;8:8.
- Abstract:
- The COVID-19 pandemic created new challenges in health care, and pathology departments have led with innovations in testing and education. While the medical community and public showed great interest in gross and histologic findings in COVID-affected patients, paradoxically many autopsy services nationwide closed due to uncertainties surrounding the proximity to infected patient tissue, shortages in personal protective equipment, and pressures to discontinue perceived nonessential hospital operations. These disruptions furthermore negatively impacted pathology trainee education. The autopsy division at Northwestern Memorial Hospital, with the belief that a fully functioning autopsy service is especially crucial at this time, adopted a framework for continuing at full capacity for both clinical care and education. New operations were modeled on national protocols by the Centers for Disease Control and Prevention and the College of American Pathologists, and the service continually adjusted policies to reflect rapidly changing guidelines and feedback from trainees and staff. Between January and December 2020, we performed 182 adult autopsies including 45 COVID-19 autopsies. Twelve residents, 4 staff, and 5 attendings rotated through the service. In exit interviews, participants expressed: (1) improved comfort managing both COVID-related and general autopsies; (2) sense of personal safety on service (despite the increased risk of exposure); (3) belief that both COVID-related and general autopsies contributed to their personal education and to the medical community. There have been zero known autopsy-related COVID-19 infections to date. We hope that our innovative autopsy service restructuring can serve as a framework for other academic programs during the current and in future pandemics.
- Keyword:
- autopsy, COVID-19, academic, resident, pandemic, education
- Subject: MESH:
- COVID-19, Autopsy, Pathology
- Subject: Name:
- Northwestern Memorial Hospital
- Creator:
- Fu, Lucy, Shanes, Elisheva Douglas, Zak, Taylor J
- Publisher:
- SAGE PUBLICATIONS INC
- Location:
- Chicago, Illinois, United States
- Language:
- English
- Date Created:
- 2021-04-07
- Rights:
- http://creativecommons.org/licenses/by-nc-nd/3.0/us/
- Resource Type:
- Anecdotes
- Original Identifier:
- (PMID) 33884293
- Title:
- Family Meetings in the Intensive Care Unit During the Coronavirus Disease 2019 Pandemic
- Original Bibliographic Citation:
- Piscitello GM, Fukushima CM, Saulitis AK, Tian KT, Hwang J, Gupta S, Sheldon M. Family Meetings in the Intensive Care Unit During the Coronavirus Disease 2019 Pandemic. American Journal of Hospice & Palliative Medicine. 2021;38(3):305-312.
- Abstract:
- Purpose: Visitor restrictions during the COVID-19 pandemic limit in-person family meetings for hospitalized patients. We aimed to evaluate the quantity of family meetings by telephone, video and in-person during the COVID-19 pandemic by manual chart review. Secondary outcomes included rate of change in patient goals of care between video and in-person meetings, the timing of family meetings, and variability in meetings by race and ethnicity. Methods: A retrospective cohort study evaluated patients admitted to the intensive care unit at an urban academic hospital between March and June 2020. Patients lacking decision-making capacity and receiving a referral for a video meeting were included in this study. Results: Most patients meeting inclusion criteria (N = 61/481, 13%) had COVID-19 pneumonia (n = 57/61, 93%). A total of 650 documented family meetings occurred. Few occurred in-person (n = 70/650, 11%) or discussed goals of care (n = 233/650, 36%). For meetings discussing goals of care, changes in patient goals of care occurred more often for in-person meetings rather than by video (36% vs. 11%, p = 0.0006). The average time to the first goals of care family meeting was 11.4 days from admission. More documented telephone meetings per admission were observed for White (10.5, SD 9.5) and Black/African-American (7.1, SD 6.6) patients compared to Hispanic or Latino patients (4.9, SD 4.9) (p = 0.02). Conclusions: During this period of strict visitor restrictions, few family meetings occurred in-person. Statistically significant fewer changes in patient goals of care occurred following video meetings compared to in-person meetings, providing support limiting in-person meetings may affect patient care.
- Keyword:
- family meetings, intensive care unit, telehealth, critical care, patient-physician communication, COVID-19
- Subject: MESH:
- COVID-19, Intensive Care Units, Telemedicine, Critical Care, Visitors to Patients
- Creator:
- Piscitello, Gina M., Fukushima, Corinna M., Saulitis, Anna K., Tian, Katherine T., Hwang, Jennifer, Gupta, Shreya, Sheldon, Mark
- Publisher:
- SAGE PUBLICATIONS INC
- Language:
- English
- Date Created:
- 2021-03
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 33207937
- Title:
- Patient Perspectives on Telepsychiatry on the Inpatient Psychiatric Unit During the COVID-19 Pandemic
- Original Bibliographic Citation:
- Heyman-Kanto R, Hardy N, Corcoran AR. Patient Perspectives on Telepsychiatry on the Inpatient Psychiatric Unit During the COVID-19 Pandemic. Journal of Patient Experience. 2020;7(5):677-679.
- Abstract:
- Hospitals have eliminated many in-person interactions and established new protocols to stem the spread of COVID-19. Inpatient psychiatric units face unique challenges, as patients cannot be isolated in their rooms and are at times unable to practice social distancing measures. Many institutions have experimented with providing some psychiatric services remotely to reduce the number of people physically present on the wards and decrease the risk of disease transmission. This case report presents 2 patient perspectives on receiving psychiatric care via videoconferencing while on the inpatient unit of a large academic tertiary care hospital. One patient identified some benefits to virtual treatment while the second found the experience impersonal; both were satisfied with the overall quality of care they received and were stable 2 weeks after discharge. These cases demonstrate that effective care can be provided remotely even to severely ill psychiatric patients who require hospitalization.
- Keyword:
- telemedicine, mental health, psychiatry, COVID-19, patient experience
- Subject: MESH:
- COVID-19, Telemedicine, Mental Health, Psychiatry, Patient Reported Outcome Measures, Qualitative Research
- Creator:
- Heyman-Kanto, Reuben, Hardy, Nathan Ellis, Corcoran, Amy Rose
- Publisher:
- SAGE PUBLICATIONS INC
- Language:
- English
- Date Created:
- 2020-10
- Rights:
- http://creativecommons.org/licenses/by-nc/3.0/us/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 33294598
- Title:
- Type I Interferon (IFN)-Regulated Activation of Canonical and Non-Canonical Signaling Pathways
- Original Bibliographic Citation:
- Mazewski C, Perez RE, Fish EN, Platanias LC. Type I Interferon (IFN)-Regulated Activation of Canonical and Non-Canonical Signaling Pathways. Frontiers in Immunology. 2020;11:13.
- Abstract:
- For several decades there has been accumulating evidence implicating type I interferons (IFNs) as key elements of the immune response. Therapeutic approaches incorporating different recombinant type I IFN proteins have been successfully employed to treat a diverse group of diseases with significant and positive outcomes. The biological activities of type I IFNs are consequences of signaling events occurring in the cytoplasm and nucleus of cells. Biochemical events involving JAK/STAT proteins that control transcriptional activation of IFN-stimulated genes (ISGs) were the first to be identified and are referred to as canonical signaling. Subsequent identification of JAK/STAT-independent signaling pathways, critical for ISG transcription and/or mRNA translation, are denoted as non-canonical or non-classical pathways. In this review, we summarize these signaling cascades and discuss recent developments in the field, specifically as they relate to the biological and clinical implications of engagement of both canonical and non-canonical pathways.
- Keyword:
- interferon, signaling, MAP kinase signaling, signal transducer and activator of transcription, mammalian target of rapamycin, mRNA translation, SARS-CoV-2, COVID-19
- Subject: MESH:
- Receptor, Interferon alpha-beta, Signal Transduction, MAP Kinase Signaling System, Sirolimus, Protein Biosynthesis, COVID-19, SARS-CoV-2
- Creator:
- Mazewski, Candice Elise, Perez, Ricardo Ernesto, Fish, Eleanor N, Platanias, Leonidas C
- Publisher:
- FRONTIERS MEDIA SA
- Language:
- English
- Date Created:
- 2020-11-23
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Review
- Original Identifier:
- (PMID) 33329603
- Title:
- Toward Accurate and Robust Environmental Surveillance Using Metagenomics
- Original Bibliographic Citation:
- Shen JX, McFarland AG, Young VB, Hayden MK, Hartmann EM. Toward Accurate and Robust Environmental Surveillance Using Metagenomics. Frontiers in Genetics. 2021;12:8.
- Abstract:
- Environmental surveillance is a critical tool for combatting public health threats represented by the global COVID-19 pandemic and the continuous increase of antibiotic resistance in pathogens. With its power to detect entire microbial communities, metagenomics-based methods stand out in addressing the need. However, several hurdles remain to be overcome in order to generate actionable interpretations from metagenomic sequencing data for infection prevention. Conceptually and technically, we focus on viability assessment, taxonomic resolution, and quantitative metagenomics, and discuss their current advancements, necessary precautions and directions to further development. We highlight the importance of building solid conceptual frameworks and identifying rational limits to facilitate the application of techniques. We also propose the usage of internal standards as a promising approach to overcome analytical bottlenecks introduced by low biomass samples and the inherent lack of quantitation in metagenomics. Taken together, we hope this perspective will contribute to bringing accurate and consistent metagenomics-based environmental surveillance to the ground.
- Keyword:
- viability, limit of detection, metagenomics, taxonomic resolution, environmental surveillance, quantitative metagenomics
- Subject: MESH:
- Metagenomics, Limit of Detection
- Creator:
- SHEN, Jiaxian, McFarland, Alexander G, Young, Vincent B, Hayden, Mary K, Hartmann, Erica Marie
- Publisher:
- FRONTIERS MEDIA SA
- Language:
- English
- Date Created:
- 2021-03-05
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 33747038
- Title:
- Respiratory Microbial Co-infection With SARS-CoV-2
- Original Bibliographic Citation:
- Massey BW, Jayathilake K, Meltzer HY. Respiratory Microbial Co-infection With SARS-CoV-2. Frontiers in Microbiology. 2020;11:7.
- Abstract:
- Co-infection with additional pathogens is a well-known feature of pandemics. We determined the prevalence and type of a wide variety of respiratory pathogens in 12,075 United States subjects tested for SARS-CoV-2 infection in March and April 2020. Infections with other respiratory pathogens, which on their own produce at least some SARS-CoV-2 symptoms including mortality, were present in both SARS-CoV-2 + and SARS-CoV-2- subjects. Non-SARS-CoV-2 infection rates were significantly higher in SARS-CoV-2 + (86%) patients than SARS-CoV-2- patients (76%) (p< 0.0001). Among the co-pathogens present in both subject groups were K. pneumoniae and M. catarrhalis which can produce serious respiratory illness on their own, Advanced age and nursing home status were associated with higher SARS-CoV-2 + and co-infection rates. Testing for the presence of co-pathogens going forward will assist in the diagnosis and optimal treatment of suspected SARS-CoV-2 respiratory infections in the current pandemic.
- Keyword:
- COVID-19, SARS-CoV-2, respiratory co-infection, K. pneumoniae, M. catarrhalis, nursing home, age, race
- Subject: MESH:
- COVID-19, SARS-CoV-2, Coinfection, Klebsiella pneumoniae, Moraxella catarrhalis, Health Services for the Aged, Nursing Homes
- Creator:
- Massey, Bill W, Jayathilake, Karu, Meltzer, Herbert Y
- Publisher:
- FRONTIERS MEDIA SA
- Language:
- English
- Date Created:
- 2020-08-25
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Article
- Original Identifier:
- (PMID) 32983056
- Title:
- One-Size-Fits All: A Scalable Solution to Formal Telemedicine Provider Training to Support the COVID-19 Pandemic Response
- Original Bibliographic Citation:
- Schinasi DA, An-Grogan Y, Stephen R, Shimek A, Furney M, Bohling MK. One-Size-Fits All: A Scalable Solution to Formal Telemedicine Provider Training to Support the COVID-19 Pandemic Response. Frontiers in Pediatrics. 2021;9:4.
- Abstract:
- Introduction: Formalized training in telemedicine addresses barriers to provider adoption and engagement and assures a level of competence for independent practice. We previously developed a blended-model training program, customizable according to role and specialty; this method of training was not feasible in the pandemic response. We describe the development and implementation of a multi- and interdisciplinary telemedicine provider training program enabling the rapid scaling of telemedicine at our institution. Methods: An existing curriculum was pared down to a 1-h session delivered synchronously, covering the foundational components of telemedicine practice. Supplemental materials were available for asynchronous learning via the hospital intranet. Completion of training was required of all clinicians who practice telemedicine. Results: We conducted 35 sessions for 1,070 providers over 12 weeks. Attendees included clinicians across numerous roles and specialties. Additional resources were created and available through the Telemedicine Virtual Handbook and housed in specific toolkits. Discussion: Telemedicine training is necessary for consistent, competent practice of telemedicine in pediatrics. We describe a training process that can be easily replicated and rapidly deployed to providers of telemedicine across roles and disciplines. Combining a mandatory and brief synchronous provider training session with a repository of online resources creates a foundation for consistent practice, while allowing for more individualized resources accessible on demand. Standardized telemedicine training followed by mechanisms for ongoing professional practice evaluation allow institutions to ensure consistent and competent practice of telemedicine. Further study is needed to determine the best modality for training, and optimal assessment tools according to professional role.
- Keyword:
- COVID-19, telemedicine, telehealth, training, education
- Subject: MESH:
- Telemedicine, COVID-19
- Subject: LCSH:
- Telecommunication in medicine, COVID-19 Pandemic, 2020-
- Creator:
- Schinasi, Dana Aronson, An-Grogan, Yuemi, Stephen, Rebecca, Shimek, Aric, Furney, Marisa, Bohling, M. Katie
- Publisher:
- FRONTIERS MEDIA SA
- Language:
- English
- Date Created:
- 2021-03-30
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Journal Article
- Original Identifier:
- (PMID) 33859970
- Title:
- The Role of Self-Efficacy and Injunctive Norms in Helping Older Adults Decide to Stay Home During the COVID-19 Pandemic
- Original Bibliographic Citation:
- Macy JT, Owens C, Mullis K, Middlestadt SE. The Role of Self-Efficacy and Injunctive Norms in Helping Older Adults Decide to Stay Home During the COVID-19 Pandemic. Frontiers in Public Health. 2021;9:8.
- Abstract:
- Purpose: Because older adults are at elevated risk of COVID-19-related adverse health outcomes, and staying at home is an effective strategy to avoid unnecessary exposures, the current formative study used the Reasoned Action Approach (RAA) to identify the beliefs underlying older adults' decision to stay home for the next month. Methods: The participants (weighted n = 206, age 65-94) for the current study were selected from a nationally representative online survey of US adults from April 10-20, 2020. We used multiple linear regression to estimate the relative contribution of the four RAA global constructs (instrumental attitude, injunctive norms, descriptive norms, and self-efficacy) in explaining intention to stay home after controlling for demographic covariates. We also conducted a content analysis to identify beliefs about advantages, disadvantages, and facilitators of staying home. Results: After controlling for demographic characteristics, injunctive norms (b = 0.208; SE = 0.059; B = 0.213, p < 0.01) and self-efficacy (b = 0.532; SE = 0.058; B = 0.537, p < 0.001) showed statistically significant independent associations with intention to stay home. The specific beliefs underlying the decision to stay home spanned across health and wellness dimensions and suggested interpersonal, mental health, and leisure/recreational facilitators. Conclusions: These findings suggest three public health intervention targets. First, self-efficacy building interventions could enhance older adults' perceptions of their ability to stay home to avoid unnecessary exposures. Second, health communication messages to address injunctive norms could emphasize that people important to older adults think they should stay home. Third, for the youngest of the older adults, health communication messages could emphasize the advantages of staying home.
- Keyword:
- older people, stay at home orders, reasoned action approach, self-efficacy, belief determinants, COVID-19
- Subject: MESH:
- COVID-19--prevention & control, Physical Distancing, Aged, Self Efficacy
- Subject: LCSH:
- COVID-19 (Disease), Social distancing (Public health), Older people, Self-efficacy
- Creator:
- Macy, Jonathan T., Owens, Christopher, Mullis, Kristina, Middlestadt, Susan E.
- Publisher:
- FRONTIERS MEDIA SA
- Language:
- English
- Date Created:
- 2021-06-04
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Journal Article
- Original Identifier:
- (PMID) 34150704
- Title:
- Commentary: GSK-3 Inhibition as a Therapeutic Approach Against SARs CoV2: Dual Benefit of Inhibiting Viral Replication While Potentiating the Immune Response
- Original Bibliographic Citation:
- De Souza A, Tavora FA, Mahalingam D, Munster PN, Safran HP, El-Deiry WS, Carneiro BA. Commentary: GSK-3 Inhibition as a Therapeutic Approach Against SARs CoV2: Dual Benefit of Inhibiting Viral Replication While Potentiating the Immune Response. Frontiers in Immunology. 2020;11:3.
- Keyword:
- glycogen synthase kinase-3 (GSK3), glycogen synthase kinase-3 (GSK-3) inhibitor, COVID-19, COVID, 9-ING-41, GSK-3b inhibitor, GSK-3 inhibitor, SARS-CoV21
- Subject: MESH:
- SARS-CoV-2, Glycogen Synthase Kinase 3, Protein Kinase Inhibitors
- Subject: LCSH:
- COVID-19 (Disease), Glycogen synthase kinase-3, Enzyme inhibitors
- Creator:
- De Souza, Andre, Tavora, Fabio A., Mahalingam, Devalingam, Munster, Pamela N., Safran, Howard P., El-Deiry, Wafik S., Carneiro, Benedito A.
- Publisher:
- FRONTIERS MEDIA SA
- Language:
- English
- Date Created:
- 2020-10-19
- Rights:
- http://creativecommons.org/licenses/by/4.0/
- Resource Type:
- Editorial
- Original Identifier:
- (PMID) 33193448
- Title:
- Calantone et al 2022 Fig S6 - Histone Mark Flow Data
- Keyword:
- immunology
- Creator:
- Calantone, Nina Alexandra
- Publisher:
- DigitalHub. Galter Health Sciences Library & Learning Center
- Rights:
- All rights reserved
- Resource Type:
- Dataset